10 Questions
What is the main characteristic of the immunoglobulin fragment produced in excess by the abnormal proliferation of plasma cells in multiple myeloma?
It is a monoclonal immunoglobulin
What is the name given to the excess immunoglobulin fragment found in the blood of patients with multiple myeloma?
Paraprotein
What technique can be used to detect the monoclonal immunoglobulin (M-band) in patients with multiple myeloma?
Serum protein electrophoresis (SPE)
What is the name given to the monoclonal free light chains found in the serum or urine of patients with multiple myeloma?
Bence-Jones protein
What is the main reason for the anemia, thrombocytopenia, and leukocytopenia seen in patients with multiple myeloma?
Expansion of malignant plasma cells in the bone marrow
What is the main cause of the osteolytic (punched-out) lesions seen in the bones of patients with multiple myeloma?
Increased activity of osteoclasts
What is the main consequence of the high plasma calcium levels seen in patients with multiple myeloma?
Osmotic diuresis, dehydration, arrhythmias, and renal problems
What is the most common site of the osteolytic lesions seen in patients with multiple myeloma?
Hip, backbones, and skull
What is the main reason for the frequent fractures seen in patients with multiple myeloma?
Osteolytic lesions in the bones
What is the main factor that can lead to coma in some cases of multiple myeloma?
High plasma calcium levels
This quiz covers hormones and diagnostic indicators related to thyroid carcinoma, including b-HCG, Calcitonin, and Thyroglobulin. Learn about their functions, significance in diagnosing medullary carcinoma of thyroid, and assessing treatment outcomes.
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