16 Questions
Where are the receptors for lipid-soluble hormones typically located?
Inside cells, typically in the nucleus
What happens when a lipid-soluble hormone binds to its receptor?
The hormone-receptor complex binds to DNA and acts as a transcription factor
What is the result of stimulated mRNA synthesis in response to lipid-soluble hormone signaling?
The synthesis of new proteins
How do thyroid hormones circulate in the blood?
Attached to plasma protein carriers
What factors influence the concentration of hormones in the blood?
The rate of release, degradation by enzymes, and excretion by the kidneys and liver
What is the effect of growth hormone on glucose utilization in the body?
decreased glucose utilization
What is the function of somatomedins or insulin-like growth factors (IGFs) in relation to growth hormone?
to mediate the effects of growth hormone
What is the effect of growth hormone hypersecretion in children?
it results in gigantism
What is the effect of growth hormone hypersecretion in adults?
it results in acromegaly
What is the effect of growth hormone deficiency in children?
it results in pituitary dwarfism
What is the function of growth hormone-releasing hormone (GHRH) in the hypothalamus?
to stimulate growth hormone secretion
What is the effect of growth hormone inhibitory hormone (GHIH) on growth hormone secretion?
it inhibits growth hormone secretion
What is the role of somatostatin in the regulation of growth hormone secretion?
it inhibits growth hormone secretion
What is the effect of growth hormone on protein synthesis in most cells of the body?
it increases protein synthesis
How is growth hormone secretion regulated in the body?
through a pulsatile pattern
What is the role of the hypothalamus in regulating growth hormone secretion?
it regulates growth hormone secretion through GHRH and GHIH
This quiz covers the binding of lipid-soluble and water-soluble hormones to receptors on the plasma membrane and intracellular receptors, and the different actions of hormones on target cells.
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