Hormonal Therapy for Breast Cancer

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Questions and Answers

What is the primary mechanism of action of hormonal therapy in treating breast cancer?

  • Promoting tumor growth by stimulating estrogen receptors
  • Blocking or destroying the estrogen receptors on cancer cells (correct)
  • Increasing the production of estrogen to feed the cancer cells
  • Destroying the ovaries to reduce estrogen production

Which of the following is a common antiestrogen drug used in the treatment of breast cancer?

  • Tamoxifen
  • Letrozole
  • Fulvestrant
  • All of the above (correct)

How does letrozole differ from tamoxifen in its mechanism of action?

  • Letrozole blocks estrogen receptors, while tamoxifen inhibits the creation of estrogen. (correct)
  • Letrozole is used for metastatic breast cancer, while tamoxifen is used for early-stage breast cancer.
  • Letrozole is given intravenously, while tamoxifen is given orally.
  • Letrozole promotes tumor growth, while tamoxifen inhibits it.

What is the primary use of fulvestrant (Faslodex) in the treatment of breast cancer?

<p>To slow the progression of advanced breast cancer by destroying estrogen receptors (B)</p> Signup and view all the answers

Which of the following is the first-line hormonal therapy for post-menopausal, estrogen receptor-positive breast cancer patients?

<p>Tamoxifen (C)</p> Signup and view all the answers

What is the primary mechanism by which hormonal therapy promotes tumor regression in breast cancer?

<p>By removing or blocking the source of estrogen, thus depriving the cancer cells of their growth-promoting stimulus (D)</p> Signup and view all the answers

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