PHY L2C HIPO PIT AXIS

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What is the role of oxytocin in response to the dilation of the cervix?

It stimulates uterine contraction

How does the number of receptors for a hormone affect the maximal response?

Increase in the number of receptors leads to an increase in maximal response

What does sensitivity refer to in the context of hormonal response?

The responsiveness of a target tissue to a hormone

How does increasing hormone concentration affect the doseresponse relationship?

It usually increases the response and then levels off

Where are the cell bodies of hypothalamic neurons located?

In the median eminence of the hypothalamus

How are hypothalamic-releasing hormones transported to the anterior pituitary?

Through hypothalamichypophysial portal blood vessels

Where do the hormones secreted by the posterior pituitary enter after release from the nerve terminals?

Fenestrated capillaries

Which organ is NOT a target tissue for oxytocin?

Pancreas

What is the term for a decrease in the number or affinity of receptors for a hormone?

Down-regulation

Which family of membrane-bound proteins couples hormone receptors to effector enzymes?

G proteins

What is the major hormone concerned with the regulation of body fluid osmolarity?

Antidiuretic hormone (ADH)

What does an increase in water permeability of principal cells in the late distal tubule and collecting duct via V2 receptors result in?

Increased water reabsorption

What is the primary function of negative feedback in hormone regulation?

To inhibit further secretion of the hormone

Where is oxytocin synthesized in the hypothalamus?

Paraventricular nuclei

Which neural mechanism causes secretion of catecholamines from the adrenal medulla?

Preganglionic sympathetic nerves

What is the effect of estrogen on the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary?

Stimulates their secretion

Test your knowledge on the hormonal regulation of uterine contraction and the role of oxytocin. Explore the relationship between dilation of the cervix, secretion of oxytocin, and uterine contraction. Also, learn about the impact of hormone receptors on target tissue response.

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