Podcast
Questions and Answers
What can induce neoplasia through receptor-mediated mechanisms and perturbation of hormonal balance?
What can induce neoplasia through receptor-mediated mechanisms and perturbation of hormonal balance?
- Non-DNA-reactive chemicals (correct)
- Enzymes
- Peptide hormones
- Antioxidants
Which hormone can induce tumors in estrogen-dependent tissues?
Which hormone can induce tumors in estrogen-dependent tissues?
- Adrenaline
- Estrogen (correct)
- Growth hormone
- Insulin
What is the mechanism of action for diethylstilbestrol (DES) in inducing changes that may lead to an abnormal number of chromosomes in a cell?
What is the mechanism of action for diethylstilbestrol (DES) in inducing changes that may lead to an abnormal number of chromosomes in a cell?
- Inducing apoptosis
- Interfering with the cell cycle and microtubule function (correct)
- Inhibiting cell proliferation
- Promoting DNA repair
Which chemicals found in soy products are considered phytoestrogens?
Which chemicals found in soy products are considered phytoestrogens?
What type of chemicals can induce tissue-specific changes through interaction with a receptor?
What type of chemicals can induce tissue-specific changes through interaction with a receptor?
What is one of the major characteristics of a neoplasm as it progresses into a malignant state?
What is one of the major characteristics of a neoplasm as it progresses into a malignant state?
Which process enables replicative immortality in neoplastic cells?
Which process enables replicative immortality in neoplastic cells?
What is a characteristic of genotoxic/DNA-reactive compounds in relation to cell proliferation?
What is a characteristic of genotoxic/DNA-reactive compounds in relation to cell proliferation?
What is the role of the tumor microenvironment in neoplastic growth and development?
What is the role of the tumor microenvironment in neoplastic growth and development?
What is a characteristic of tumor promotion by carcinogens?
What is a characteristic of tumor promotion by carcinogens?
What characterizes the selective clonal expansion of initiated cells in the formation of preneoplastic lesions?
What characterizes the selective clonal expansion of initiated cells in the formation of preneoplastic lesions?
Which mechanism of action is associated with chemicals that induce cytotoxicity and persistent regenerative growth, potentially leading to DNA mutations?
Which mechanism of action is associated with chemicals that induce cytotoxicity and persistent regenerative growth, potentially leading to DNA mutations?
Which chemical is an example of a substance that functions through cytotoxicity as a mode of action in chemical carcinogenesis?
Which chemical is an example of a substance that functions through cytotoxicity as a mode of action in chemical carcinogenesis?
Which mechanism of action involves chemicals that can alter the methylation status, contributing to neoplasia progression?
Which mechanism of action involves chemicals that can alter the methylation status, contributing to neoplasia progression?
Which receptor is associated with chemicals that act through a receptor-mediated mode of action in chemical carcinogenesis?
Which receptor is associated with chemicals that act through a receptor-mediated mode of action in chemical carcinogenesis?
Which compound acts as an oxidative stress inducer, potentially contributing to the development of cancer?
Which compound acts as an oxidative stress inducer, potentially contributing to the development of cancer?
Which chemical poses a risk of immunosuppression, potentially affecting the tumor microenvironment?
Which chemical poses a risk of immunosuppression, potentially affecting the tumor microenvironment?
