Chapter 35 words in blue
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Chapter 35 words in blue

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Questions and Answers

Refers to the steady state of the pH of the body

Acid-base balance

When the pH value of body fluids is <7.3, characterized by excess hydrogen ions

Acidosis

When the pH value is >7.4, characterized by a low hydrogen ion concentration

Alkalosis

Substances that can alter hydrogen ion concentration

<p>Buffers</p> Signup and view all the answers

If respiratory rate decreases the rate at which carbon dioxide is eliminated decreases. The excess carbon dioxide reacts with water to form carbonic acid, which then dissociates into water and hydrogen ions. This will be evidenced in part by an increased partial pressure of carbon dioxide PCO2, which is known as ?

<p>Hypercapnia</p> Signup and view all the answers

Abnormalities in the respiratory system that cause an increase in respiratory rate (hyperventilation) result in a decrease in the concentration of carbon dioxide in the blood and a subsequent decrease in PCO3 in the blood, which is called ?

<p>Hypocapnia</p> Signup and view all the answers

The amount of strong acid or base that is required to titrate 1 L of blood to a pH of 7.4 at 37C while the PCO2 is held constant at 40 mm Hg - is called

<p>Base excess</p> Signup and view all the answers

Conditions associated with altered sodium or potassium concentration

<p>Water deprivation, hyperventilation, osmotic diuresis = Hypernatremia GI disorders (vomit/diarrhea), ketonuria, hypoadrenocorticism, congestive heart failure = Hyponatremia Metabolic acidosis, urinary tract obstruction, renal insufficiency = Hyperkalemia Anorexia, ketonuria, diuresis = Hypokalemia</p> Signup and view all the answers

Match

<p>Elevated blood level of sodium = Hypernatremia Decreased blood level of sodium = Hyponatremia Elevated plasma potassium levels = Hyperkalemia Decreased plasma potassium levels = Hypokalemia</p> Signup and view all the answers

Match

<p>May happen in the presence of cellular damage or necrosis = Hyperkalemia May be associated with inadequate potassium intake, alkalosis or fluid loss due to vomiting and diarrhea = Hypokalemia Elevated blood magnesium level = Hypermagnesemia Decreased blood magnesium levels = Hypomagnesemia</p> Signup and view all the answers

Samples for calcium testing should not be collected using ____, because it binds to calcium and makes it unavailable for assay

<p>EDTA</p> Signup and view all the answers

Match

<p>Elevated blood calcium concentration = Hypercalcemia Decreased blood calcium concentration = Hypocalcemia Increased serum or plasma phosphorus concentration = Hyperphosphatemia Decreased serum or plasma phosphorus concentration = Hypophosphatemia</p> Signup and view all the answers

Study Notes

Acid-Base Balance

  • Refers to the steady state of the pH of the body

Acidosis

  • Characterized by excess hydrogen ions when the pH value of body fluids is <7.3

Alkalosis

  • Characterized by a low hydrogen ion concentration when the pH value is >7.4

Factors Affecting Hydrogen Ion Concentration

  • Substances that can alter hydrogen ion concentration
  • Respiratory rate: decreased rate leads to excess carbon dioxide, forming carbonic acid, and increasing hydrogen ions and PCO2
  • Respiratory rate: increased rate (hyperventilation) leads to decreased carbon dioxide in the blood, decreasing PCO2

Respiratory Acidoses

  • Result from decreased respiratory rate, causing increased PCO2

Respiratory Alkaloses

  • Result from increased respiratory rate (hyperventilation), causing decreased PCO2

Buffering Capacity

  • The amount of strong acid or base required to titrate 1 L of blood to a pH of 7.4 at 37°C while PCO2 is held constant at 40 mm Hg

Electrolyte Imbalances

  • Conditions associated with altered sodium or potassium concentration

Calcium Testing

  • Samples should not be collected using oxalate, as it binds to calcium and makes it unavailable for assay

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