Homeostasis in Mammals

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Questions and Answers

What is the primary function of homeostasis in organisms?

  • To increase enzyme efficiency
  • To create new cells
  • To maintain equilibrium around a set point (correct)
  • To destroy waste materials

What happens to enzymes when there are changes in pH and temperature?

  • They perform better during extreme conditions
  • They become more efficient
  • They replicate faster
  • They may denature and cease functioning (correct)

Which of the following accurately describes excretion?

  • The removal of undigested food
  • The transport of nutrients into cells
  • The synthesis of proteins
  • The removal of waste products of metabolism (correct)

What is the role of the liver in the formation of urea?

<p>It synthesizes urea from excess amino acids (C)</p> Signup and view all the answers

In the urea cycle, what is ammonia converted into?

<p>Urea (B)</p> Signup and view all the answers

Which waste product do adult humans produce in significant quantities each day?

<p>Carbon dioxide (C)</p> Signup and view all the answers

What process involves the removal of amino groups from amino acids to form ammonia?

<p>Deamination (B)</p> Signup and view all the answers

What may happen to cells if there are changes in water potential in the body?

<p>Cells may swell, shrink, or burst (A)</p> Signup and view all the answers

What is the primary role of homeostasis in mammals?

<p>To maintain a constant internal environment (A)</p> Signup and view all the answers

Which of the following systems is responsible for rapid communication in multicellular organisms?

<p>Nervous system (D)</p> Signup and view all the answers

What defines the term 'negative feedback' in the context of homeostasis?

<p>A mechanism that stabilizes physiological variables (C)</p> Signup and view all the answers

Which component is NOT a part of the homeostatic mechanism?

<p>Proteins (D)</p> Signup and view all the answers

How does the endocrine system differ from the nervous system in terms of communication?

<p>The endocrine system provides slower and less specific communication (B)</p> Signup and view all the answers

What purpose do extracellular fluids serve in multicellular organisms?

<p>To provide nutrients and remove waste (C)</p> Signup and view all the answers

What is a significant outcome of the specialization of cells in multicellular organisms?

<p>Increased efficiency through division of labor (A)</p> Signup and view all the answers

What is primarily maintained through homeostasis in terms of blood and tissue fluid?

<p>Narrow limits for chemical composition and volume (B)</p> Signup and view all the answers

What is the main function of the afferent arteriole in the nephron?

<p>To supply blood to the nephron (D)</p> Signup and view all the answers

Which structure is responsible for filtering blood in the nephron?

<p>Glomerulus (A)</p> Signup and view all the answers

What is the role of the efferent arteriole in the nephron?

<p>It collects blood from the glomerulus (A)</p> Signup and view all the answers

What process is involved in the conversion of ammonia to urea?

<p>Ureogenesis (D)</p> Signup and view all the answers

What occurs within the peritubular capillaries in the nephron?

<p>Reabsorption of mineral salts, glucose, and water (C)</p> Signup and view all the answers

Which part of the kidney surrounds the nephron and has a lighter color?

<p>Cortex (A)</p> Signup and view all the answers

Which vessel brings blood to the kidney?

<p>Renal artery (D)</p> Signup and view all the answers

What is excretion primarily concerned with?

<p>Eliminating metabolic waste products (C)</p> Signup and view all the answers

Why can freshwater fish utilize ammonia as their nitrogenous waste product?

<p>They have access to large volumes of water. (A)</p> Signup and view all the answers

What is the main reason birds and reptiles use uric acid for waste removal?

<p>It prevents toxicity to developing young in eggs. (A)</p> Signup and view all the answers

Which component of the nephron is responsible for filtering blood?

<p>Renal (Bowman's) capsule (D)</p> Signup and view all the answers

What distinguishes the proximal convoluted tubule from the distal convoluted tubule?

<p>The proximal tubule has more blood capillaries. (A)</p> Signup and view all the answers

How many ATP molecules are required for the production of uric acid?

<p>7 (C)</p> Signup and view all the answers

What characterizes the Loop of Henlé in terms of its structure and location?

<p>It connects the proximal and distal convoluted tubules. (D)</p> Signup and view all the answers

What is the primary function of podocytes in the nephron?

<p>To prevent the loss of large proteins in the urine. (A)</p> Signup and view all the answers

Why is uric acid considered less toxic compared to ammonia?

<p>It cannot diffuse into cells. (B)</p> Signup and view all the answers

Flashcards

Homeostasis

The ability of an organism to maintain a stable internal environment, despite changes in the external environment.

Extracellular Fluid

The fluid that surrounds and bathes all cells in the body, providing nutrients and removing waste products.

Homeostatic Mechanism

The complex process by which organisms maintain a constant internal environment, involving multiple factors like temperature, pH, and blood sugar.

Nervous System

A system that allows rapid, targeted communication between specific parts of the body, using electrical impulses.

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Endocrine System

A system that uses hormones to communicate throughout the body, often slower and with broader effects.

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Negative Feedback

A mechanism that reduces deviation from a set point, bringing the body back to equilibrium.

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Receptors

Specialized cells, tissues, or organs that detect changes in the internal environment.

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Effectors

Specialized cells or tissues that carry out responses to maintain homeostasis, often muscles or glands.

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Nephron

The functional unit of the kidney, a narrow tube responsible for filtering blood and producing urine.

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Renal (Bowman's) Capsule

The closed end of the nephron, cup-shaped and containing the glomerulus, a network of capillaries where filtration begins.

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Glomerulus

A network of blood capillaries located within the renal capsule, where filtration of blood occurs.

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Podocytes

Specialized cells lining the inner layer of the renal capsule, forming filtration slits.

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Proximal Convoluted Tubule

The first segment of the nephron after the renal capsule, where most reabsorption occurs.

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Loop of Henle

The long, hairpin-shaped loop extending from the cortex into the medulla and back, responsible for concentrating the filtrate.

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Distal Convoluted Tubule

The second segment of the nephron, where further reabsorption and secretion take place.

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Collecting Duct

A tube that collects filtrate from multiple distal convoluted tubules, transporting it to the ureter.

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What is homeostasis?

The ability of an organism to maintain a stable internal environment.

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What is a set point?

A set point is the desired value of a factor like temperature, pH, or blood sugar.

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What is a stimulus?

A change in internal conditions, such as a drop in body temperature, that triggers a response to maintain homeostasis.

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What are receptors?

The system that detects changes in the environment and sends signals to the control center to initiate a response.

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What is the control center?

The part of the body that receives information from receptors and coordinates the response.

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What are effectors?

The part of the body that carries out the response to maintain homeostasis.

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What is negative feedback?

The process by which the body reduces deviation from a set point, bringing the body back to equilibrium.

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What is deamination?

The breakdown of amino acids to remove their amino groups (NH2) and produce ammonia.

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Afferent Arteriole

A tiny vessel that branches from the renal artery and delivers blood to the nephron.

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Efferent Arteriole

A tiny vessel exiting the renal capsule, carrying blood away from the glomerulus, with a smaller diameter than the afferent arteriole – causing higher pressure in the glomerulus.

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Peritubular Capillaries

A network of capillaries surrounding the nephron tubules, reabsorbing water, glucose, and mineral salts from the filtered fluid.

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Deamination

The process of removing nitrogenous waste from amino acids.

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Urea Cycle

The process of converting ammonia to urea, using carbon dioxide.

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Renal Cortex

The outer region of the kidney containing the renal corpuscles and convoluted tubules.

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Renal Medulla

The inner region of the kidney containing the loop of Henle and collecting ducts.

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Study Notes

Homeostasis in Mammals

  • Homeostasis is the maintenance of a relatively constant internal environment in organisms. It's crucial for cells to function normally regardless of external changes.
  • Homeostasis maintains the chemical makeup, volume, and other features of blood and tissue fluid within narrow limits (normal ranges).
  • Homeostasis ensures cells are in an environment suitable for their functions.
  • Despite constant fluctuations in the internal/external conditions, homeostasis works to keep conditions around a set point.

Importance of Homeostasis

  • Enzymes and proteins (like membrane channels) are sensitive to pH and temperature changes. Variations reduce enzyme efficiency or can lead to denaturation. Membrane protein changes also affect substance transport.
  • Water potential changes in blood/tissue fluids can cause cell shrinkage or swelling (bursting), hindering normal cell operation.

Control Mechanisms and Feedback

  • Control of systems involves stages:
    • A set point (desired level) is monitored by receptors detecting internal/external stimuli.
    • Deviation from the set point triggers signal transmission to the central control.
    • The central control coordinates and sends instructions to effectors (muscles/glands).
    • Effectors carry out changes needed to return to the set point.
  • Feedback loops inform the receptors about changes resulting from effector actions, thus closing the loop. A negative feedback loop is common, turning off the system when the set point has been reached.
  • Positive feedback is less common. A positive feedback loop increases the deviation from the set point.

Coordination of Control Mechanisms

  • Multiple receptors and effectors in a system are crucial.
  • The central control needs to process information from various sources to manage the effectors effectively. For instance, temperature regulation involves analysis of sensory input from across the body and within the brain to coordinate responses (like sweating or vasodilation).

Excretion & Kidney Structure

  • Excretion is the removal of metabolic waste from the body; distinct from elimination (removal of non-metabolic substances).
  • Urea is a major nitrogenous excretory product in mammals. It's formed in the liver from excess amino acids in a three-stage process (deamination, ammonia formation, urea synthesis).
  • The kidney's structure includes a fibrous capsule, cortex, medulla, renal pelvis, ureter, renal artery, and renal vein which work together to filter blood and produce urine.

Structure of the Nephron

  • The nephron is the functional unit of the kidney.
  • It comprises a renal corpuscle (Bowman's capsule and glomerulus) and a series of tubules (proximal convoluted tubule, loop of Henlé, distal convoluted tubule, and collecting duct).
  • Blood vessels (afferent arteriole, glomerulus, efferent arteriole, peritubular capillaries) are intimately associated with the nephron, enabling blood filtration and reabsorption.

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