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Questions and Answers
Which of the following best describes negative feedback mechanisms?
Which of the following best describes negative feedback mechanisms?
Which directional term refers to a structure being located towards the front of the body?
Which directional term refers to a structure being located towards the front of the body?
In the context of blood glucose regulation, what role does negative feedback play?
In the context of blood glucose regulation, what role does negative feedback play?
Which structural level of the hierarchy refers to a group of tissues that work together to perform specific functions?
Which structural level of the hierarchy refers to a group of tissues that work together to perform specific functions?
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What is the primary function of positive feedback mechanisms during uterine contractions in labor?
What is the primary function of positive feedback mechanisms during uterine contractions in labor?
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What is the primary function of a buffer in biological systems?
What is the primary function of a buffer in biological systems?
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Which of the following describes the general chemical equation for cellular respiration?
Which of the following describes the general chemical equation for cellular respiration?
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In comparing glycolysis, the Krebs cycle, and the electron transport chain, which statement about energy production is accurate?
In comparing glycolysis, the Krebs cycle, and the electron transport chain, which statement about energy production is accurate?
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How does anaerobic respiration differ from aerobic respiration in terms of energy efficiency?
How does anaerobic respiration differ from aerobic respiration in terms of energy efficiency?
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Which location in the cell is primarily associated with the Krebs cycle?
Which location in the cell is primarily associated with the Krebs cycle?
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What characterizes a hypertonic solution in relation to a cell?
What characterizes a hypertonic solution in relation to a cell?
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Which membrane protein is primarily responsible for allowing specific ions to flow through the plasma membrane without the need for energy?
Which membrane protein is primarily responsible for allowing specific ions to flow through the plasma membrane without the need for energy?
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What is the primary function of transcription in the process of protein synthesis?
What is the primary function of transcription in the process of protein synthesis?
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What is one characteristic that distinguishes connective tissue from other tissue types?
What is one characteristic that distinguishes connective tissue from other tissue types?
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Which of the following best describes the role of cell-identity markers?
Which of the following best describes the role of cell-identity markers?
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Which function of the skeletal system is primarily responsible for protecting vital organs?
Which function of the skeletal system is primarily responsible for protecting vital organs?
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How do compact bone and spongy bone differ in their structural arrangement?
How do compact bone and spongy bone differ in their structural arrangement?
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Which of the following correctly distinguishes between intramembranous and endochondral ossification?
Which of the following correctly distinguishes between intramembranous and endochondral ossification?
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What type of joint is characterized by a joint cavity and movement in various directions?
What type of joint is characterized by a joint cavity and movement in various directions?
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What is the major difference between the axial and appendicular divisions of the skeletal system?
What is the major difference between the axial and appendicular divisions of the skeletal system?
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What is one function of the skeletal system?
What is one function of the skeletal system?
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Which tissue types are found in bones and how are they arranged?
Which tissue types are found in bones and how are they arranged?
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Which statement accurately distinguishes between intramembranous ossification and endochondral ossification?
Which statement accurately distinguishes between intramembranous ossification and endochondral ossification?
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Which of the following statements is true regarding synovial joints?
Which of the following statements is true regarding synovial joints?
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What distinguishes the axial skeleton from the appendicular skeleton?
What distinguishes the axial skeleton from the appendicular skeleton?
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Which characteristic of muscle cells allows them to respond to stimuli?
Which characteristic of muscle cells allows them to respond to stimuli?
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What is the innermost connective tissue layer surrounding a muscle fiber called?
What is the innermost connective tissue layer surrounding a muscle fiber called?
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Which term describes the connection point between a motor neuron and a muscle fiber?
Which term describes the connection point between a motor neuron and a muscle fiber?
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What is the function of acetylcholinesterase in the neuromuscular junction?
What is the function of acetylcholinesterase in the neuromuscular junction?
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Which energy source is utilized for short-term muscle contraction during intense activities?
Which energy source is utilized for short-term muscle contraction during intense activities?
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Study Notes
Skeletal System
5 Major Functions of the Skeletal System
- Support: Provides a structural framework for the body.
- Protection: Encases vital organs (brain, lungs, heart).
- Movement: Muscles attach to bones to produce movement at joints.
- Blood Cell Production: Hematopoiesis occurs in bone marrow, producing blood cells.
- Mineral Storage: Stores and releases calcium and phosphorus as needed by the body.
Bone Tissue Arrangement
- Compact Bone: Arranged in osteons, cylindrical units with concentric layers (lamellae). This creates a strong and dense structure.
- Spongy Bone: Composed of trabeculae, a network of bony struts. This creates a lightweight, porous structure supporting bone marrow.
Tissues Found in Bones
- Cartilage: Covers articular surfaces of bones at joints, reducing friction.
- Dense Connective Tissue: Forms ligaments and tendons, attaching bones to bones (ligaments) and muscles to bones (tendons); provides structural stability.
- Compact Bone: Provides strength, found in shafts and coverings of bones.
- Spongy Bone: Found in the interior of bones, with a lattice-like structure for support with less mass.
Ossification (Bone Development)
- Intramembranous Ossification: Bone develops directly from mesenchymal (undifferentiated) connective tissue. This is common in flat bones (e.g., skull).
- Endochondral Ossification: Bone develops by replacing hyaline cartilage models. This is typical for long bones.
Chemical Agents Affecting Bone Tissue
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Calcium: Essential for bone strength; tightly regulated by hormonal mechanisms, preventing imbalances disrupting bone health.
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Hormonal Regulation:
- Parathyroid Hormone (PTH): Increases blood calcium by increasing calcium reabsorption from bones and kidneys, and vitamin D increases calcium absorption in the gut.
- Calcitonin: Lowers blood calcium by increasing calcium deposition into bones.
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Hormonal Regulation:
- Other factors: Phosphorus and other minerals, overall growth, and development factors also affect bone tissue.
Types of Joints
- Suture: Immovable fibrous joints, found in the skull.
- Gomphosis: Immovable fibrous joints, like teeth in sockets.
- Syndesmosis: Slightly movable fibrous joints.
- Synchondrosis: Cartilaginous joint, slightly movable, typically temporary (e.g., rib attachment to sternum—costochondral junctions).
- Symphysis: Cartilaginous joint, slightly movable, with fibrocartilaginous disc (e.g., pubic symphysis).
- Synovial: Freely movable joints with synovial fluid, articular cartilage, ligaments, and accessory structures.
Structures in Synovial Joints
- Synovial Membrane: Lines the joint capsule, secreting synovial fluid for lubrication.
- Articular Cartilage: Covers articular surfaces of bones, reducing friction.
- Ligament: Tough band of connective tissue, reinforcing the joint and restricting movement.
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Accessory Structures:
- Meniscus: C-shaped pads of cartilage providing cushioning and stability within the joint.
- Bursae: Fluid-filled sacs that reduce friction between moving structures around a joint.
- Adipose Tissue: Pads found in and around joints further cushioning structures.
Divisions of the Skeletal System
- Axial Skeleton: Forms the central axis of the body; includes the skull, vertebral column, and ribs.
- Appendicular Skeleton: Includes the limbs and the pectoral (shoulder) and pelvic girdles.
Muscular System
5 Functions of Skeletal Muscle
- Movement: Produces skeletal movement.
- Maintain Posture: Maintains body position.
- Stabilize Joints: Assists in stabilizing joints.
- Generate Heat: Produces heat through contraction.
- Guard Entrances/Exits: Controls passageways like the digestive system.
Characteristics of Muscle Cells
- Excitability: Ability to respond to stimuli.
- Contractility: Ability to shorten forcefully.
- Extensibility: Ability to be stretched.
- Elasticity: Ability to recoil to resting length.
General Structure of Skeletal Muscle
- Endomysium: Connective tissue surrounding each muscle fiber.
- Perimysium: Connective tissue surrounding fascicles (bundles of muscle fibers).
- Fascicle: A bundle of muscle fibers.
- Epimysium: Connective tissue surrounding the entire muscle.
- Fasciae: Sheets of connective tissue surrounding groups of muscles.
- Tendons: Connective tissue cords that attach muscle to bone.
- Aponeurosis: Connective tissue sheet that attaches muscle to bone or other muscles.
Microanatomy of a Muscle Cell
- Sarcoplasm: Cytoplasm of a muscle cell.
- Glycogen: Stores energy for muscle contraction.
- Myoglobin: Stores oxygen for muscle contraction.
- Sarcolemma: Plasma membrane of a muscle cell.
- Transverse Tubules (T-tubules): Invaginations of sarcolemma that allow for rapid signal transmission into the cell.
- Sarcoplasmic Reticulum (SR): Specialized endoplasmic reticulum storing and releasing calcium ions. (Terminal Cisternae are enlargements of the SR).
- Thick Filaments: Composed of myosin protein.
- Myosin: Protein responsible for the movement of thick filaments.
- Thin Filaments: Composed of actin, tropomyosin, and troponin proteins.
- Actin: Protein that interacts with myosin for contraction.
- Tropomyosin: Protein that blocks myosin binding sites on actin in a relaxed muscle.
- Troponin: Protein that binds to tropomyosin and actin, regulating muscle contraction.
- A Band: Region of sarcomere containing both thick and thin filaments.
- H Band: Region of sarcomere containing only thick filaments.
- I Band: Region of sarcomere containing only thin filaments.
- Z Disc/Line: Separates adjacent sarcomeres.
- Cross-Bridge: The connection between myosin heads and actin filaments during contraction.
Motor Unit
- Motor Unit: A motor neuron and all the muscle fibers it controls.
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Components:
- Motor neuron
- Muscle fibers
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Neuromuscular Junction (NMJ):
- Synaptic Knob: Expanded end of the motor neuron.
- Synaptic Vesicles: Contain acetylcholine (Ach).
- Synaptic Cleft: Gap between the synaptic knob and muscle fiber.
- Junctional Folds: Invaginations of the muscle fiber's sarcolemma.
- Receptor Proteins: Respond to acetylcholine.
- Acetylcholine (ACh): Neurotransmitter that stimulates muscle contraction.
- Acetylcholinesterase (AChE): Enzyme that breaks down acetylcholine, terminating the signal.
Excitation-Contraction-Relaxation Coupling
- Threshold Stimulus: Minimum stimulus required to cause a muscle contraction.
- Latent Period: Delay between stimulus and the beginning of contraction.
- Refractory Period: Time muscle cannot be stimulated again.
Energy Sources for Muscle Activity
- Initial (Myokinase and Creatine Kinase): Immediate energy from stores of creatine phosphate.
- Short-Term/Secondary: Anaerobic glycolysis, producing ATP and lactate.
- Long-Term: Aerobic respiration, producing ATP from glucose or fatty acids.
- Muscle Fatigue: Inability to maintain muscle tension.
- Oxygen Debt: Amount of oxygen needed to return muscle to resting state after strenuous activity.
Specific Muscle Groups
- Rotator Cuff: Supraspinatus, infraspinatus, subscapularis, teres minor
- Quadriceps Femoris: Rectus femoris, vastus lateralis, vastus medialis, vastus intermedius
- Hamstrings: Biceps femoris, semimembranosus, semitendinosus
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Description
This quiz covers the concepts of homeostasis and stress, emphasizing the body's ability to maintain internal balance amidst external changes. It also delves into negative feedback mechanisms involved in regulating blood pressure and glucose levels.