Cyclopia and Synophthalmia
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Questions and Answers

Which of the following best describes cyclopia?

  • Formation of globes in the posterior third of the embryonic disc
  • Formation of two incompletely separated or fused globes
  • Formation of a single median globe (correct)
  • Formation of multiple globes

    • What is the main cause of cyclopia?

  • Ingestion of the alk
  • Loss of midline territory in the embryo
  • Formation of bilateral optic vesicles
  • Defect in separation of the anterior third of the embryonic disc (correct)

    • What is synophthalmia characterized by?

  • Formation of two incompletely separated or fused globes (correct)
  • Formation of globes in the posterior third of the embryonic disc
  • Formation of a single median globe
  • Formation of multiple globes

    • What is the usual outcome for cases of cyclopia or synophthalmia?

    <p>Severe craniofacial malformations</p> Signup and view all the answers

    Which of the following alkaloids is responsible for causing cyclopia in sheep?

    <p>Cyclopamine</p> Signup and view all the answers

    At what stage of gestation in sheep does veratrum-induced cyclopia occur?

    <p>Day 14</p> Signup and view all the answers

    What is the specific timing for veratrum-induced cyclopia in sheep?

    <p>During gastrulation and formation of the neural plate</p> Signup and view all the answers

    What happens if sheep are exposed to the alkaloid earlier in gestation?

    <p>Fetal death</p> Signup and view all the answers

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