HIV Retroviruses and Perinatal Transmission

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What enzyme do HIV Retroviruses encode?

Reverse transcriptase (RT)

How do HIV Retroviruses replicate?

Through a DNA intermediate

What are the risk factors for perinatal transmission of HIV?

Prematurity and high maternal circulating levels of HIV at delivery

How is the viral genome of HIV integrated into the host chromosome?

It integrates into the host chromosome to become a cellular gene

When is combination therapy with highly active antiretroviral therapy (HAART) recommended for HIV treatment?

Based on the risk of disease progression determined by CD4 percentage or count and plasma HIV RNA copy number

Learn about the characteristics of HIV retroviruses, their replication process, integration into the host chromosome, and risk factors for perinatal transmission. Understand how the virus can be transmitted through blood and ways to prevent transmission.

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