History of Leech Therapy

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Questions and Answers

What is one of the primary purposes of the substances found in leech saliva?

  • To enhance pain sensitivity
  • To increase blood clotting
  • To inhibit bacterial growth (correct)
  • To accelerate wound healing

Which of the following conditions makes leech therapy unsuitable?

  • Anemia (correct)
  • High blood pressure
  • Bacterial infection
  • Homophilia

What effect does leech saliva have on the coagulation process?

  • Enhances blood clot formation
  • Increases fibrinogen production
  • Prevents platelet aggregation (correct)
  • Stimulates rapid blood flow

What is considered a common side effect of leech therapy?

<p>Mild pain (B)</p> Signup and view all the answers

Which of the following is a rare side effect of leech therapy?

<p>Skin infection (C)</p> Signup and view all the answers

What is the primary purpose of leech therapy?

<p>To use leeches in the treatment of medical conditions (B)</p> Signup and view all the answers

Which compound in leech saliva is known for its anticoagulating properties?

<p>Hirudin (A)</p> Signup and view all the answers

Which of the following effects is NOT associated with leech therapy?

<p>Nutritional enhancement (C)</p> Signup and view all the answers

Which effect results from the leech's ability to break up fibrins?

<p>Thrombolytic effect (C)</p> Signup and view all the answers

Which compounds in leech saliva act as vasodilators?

<p>Histamine, acetylcholine, and carboxypeptides (D)</p> Signup and view all the answers

What is the anti-inflammatory action of bdellins primarily due to?

<p>Inhibiting the action of trypsin (C)</p> Signup and view all the answers

Which historical figure is associated with the introduction of leeches in traditional medicine?

<p>Dhanvanthari (C)</p> Signup and view all the answers

What type of animals are leeches classified as?

<p>Carnivorous aquatic or terrestrial worms (D)</p> Signup and view all the answers

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Study Notes

History of Leech Therapy

  • Leech therapy is one of the oldest healing methods documented in medical history.
  • Historically associated with Dhanvanthari, a key figure in traditional Indian medicine, who symbolizes the balance of healing with leeches and nectar.

Definition

  • Leech therapy involves the use of leeches to treat various medical conditions.
  • Leeches are carnivorous aquatic or terrestrial worms with two suckers, one on each end.

Benefits

  • Anti-coagulating: Leeches' saliva contains "hirudin," an enzyme that inhibits blood coagulation by binding to thrombin.
  • Clot dissolving: Salivary compounds have thrombolytic effects, facilitating the breakdown of fibrins and dissolving blood clots.
  • Anti-inflammatory: Bdellins in saliva inhibit trypsin and plasmin, effectively reducing inflammation.
  • Vasodilating: Compounds like histamine, acetylcholine, and carboxypeptides help widen blood vessels, increasing blood flow.
  • Bacteriostatic and Anesthetic: Saliva contains substances that numb pain at the application site and inhibit bacterial growth.

Contraindications

  • Not suitable for individuals with:
    • Hemophilia
    • Use of anticoagulant medications (e.g., Warfarin, Heparin, Marcumar)
    • Anemia
    • Erosive gastritis
    • Acute infectious diseases
    • Severe allergic diathesis

Mechanism of Action

  • Leeches possess various proteins in their saliva with unique properties affecting the coagulation cascade.
  • They inhibit the conversion of fibrinogen to fibrin and reduce platelet aggregation.
  • Analgesic effects are provided, reducing pain and numbness.

Side Effects

  • Common side effects:
    • Mild pain at the bite site
    • Prolonged bleeding
    • Itching and redness surrounding the bite area
  • Rare side effects:
    • Skin infections
    • Temporary enlargement of lymph nodes
    • Pigmentation disorders
    • Temporary swelling of tissues

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