History of Evolutionary Theory
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Questions and Answers

What was the major flaw in the preformationist theory?

  • It proposed that a tiny homunculus was present in the sperm or egg (correct)
  • It was only applicable to animals, not plants
  • It was unable to explain the mechanism of heredity
  • It did not account for variation in offspring
  • Who is associated with the theory of Epigenesis?

  • Weismann
  • Lamarck
  • Caspar F.Wolff & Karl Ernst von Baer (correct)
  • Darwin
  • What was the significance of Jan Swammerdam and Charles Bonnet's work?

  • They developed the theory of Pangenesis
  • They discovered the existence of sex cells
  • They proposed the theory of Lamarckism
  • They contributed to the development of the preformationist theory (correct)
  • What is the main idea behind the Germplasm theory?

    <p>The theory that heredity is determined by the germplasm</p> Signup and view all the answers

    Who is credited with the development of the theory of Mendelism?

    <p>Mendel</p> Signup and view all the answers

    What is the main difference between the 'spermatist' and the 'ovist'?

    <p>The 'spermatist' believed that the homunculus was present in the sperm, while the 'ovist' believed it was present in the egg</p> Signup and view all the answers

    What is the main idea behind Lamarckism?

    <p>The idea that acquired traits can be inherited</p> Signup and view all the answers

    What was the significance of Charles Darwin's work in the context of heredity?

    <p>He developed the theory of Pangenesis</p> Signup and view all the answers

    What is always used as one of the parents in a testcross?

    <p>Recessive homozygote</p> Signup and view all the answers

    What is the main difference between testcross and backcross?

    <p>Use of recessive homozygote as a parent</p> Signup and view all the answers

    What is the genotype of the offspring in a testcross?

    <p>Dd</p> Signup and view all the answers

    What is the purpose of a testcross?

    <p>To study the principles of segregation</p> Signup and view all the answers

    What is true about backcross?

    <p>It is not necessarily true that a recessive homozygote is used as a parent</p> Signup and view all the answers

    What is the expected ratio of a monohybrid cross?

    <p>3:1</p> Signup and view all the answers

    What is the difference between the genotype of the parents in a testcross and backcross?

    <p>Testcross has homozygous recessive and backcross has heterozygous</p> Signup and view all the answers

    What is the significance of a testcross?

    <p>It helps in studying the principles of segregation</p> Signup and view all the answers

    What is the name of the law of probability that relates to the operation of two monohybrid crosses?

    <p>Product Rule</p> Signup and view all the answers

    What is the significance of a 9:3:3:1 ratio in experiments?

    <p>It indicates that two independent pairs of alleles are involved</p> Signup and view all the answers

    What is the genotype of the other parent in a testcross?

    <p>Dd</p> Signup and view all the answers

    What is the outcome of a testcross?

    <p>All offspring are heterozygous</p> Signup and view all the answers

    What type of cross is represented by the genotype AABBCC X aabbcc?

    <p>Trihybrid cross</p> Signup and view all the answers

    What is the main advantage of a testcross?

    <p>It helps in studying the principles of segregation</p> Signup and view all the answers

    What is the genotype of the seed parent in the trihybrid ratio example?

    <p>DDGGWW</p> Signup and view all the answers

    What is the phenotype of the gamete RrYy?

    <p>Round, yellow</p> Signup and view all the answers

    What is the purpose of understanding the principle of dihybrid and trihybrid crosses in plant and animal breeding?

    <p>To improve the quantity and quality of agricultural and animal products</p> Signup and view all the answers

    What is the ratio of the genotypic frequency to the phenotypic frequency in the dihybrid backcross?

    <p>1:1</p> Signup and view all the answers

    What is the formula to calculate the probability of a binomial distribution?

    <p>P = (n!/s!t!)(psqt)</p> Signup and view all the answers

    What is the probability that two babies out of four will be boys and two will be girls?

    <p>10/32</p> Signup and view all the answers

    What is the probability that all four babies will be girls?

    <p>1/32</p> Signup and view all the answers

    What is the probability that a given child will be normal if the parents are heterozygous for albinism?

    <p>1/2</p> Signup and view all the answers

    What is the probability that all four children will be normal if the parents are heterozygous for albinism?

    <p>1/16</p> Signup and view all the answers

    What is the probability that all four children will be normal except the 2nd child if the parents are heterozygous for albinism?

    <p>3/16</p> Signup and view all the answers

    What is the condition for two events to be independent in probability?

    <p>The probability of one event does not affect the probability of the other event</p> Signup and view all the answers

    What is the concept of studying the probability of multiple genetic events?

    <p>Probability of multiple events</p> Signup and view all the answers

    What is the purpose of a testcross in genetics?

    <p>To determine the genotype of an individual organism</p> Signup and view all the answers

    What is the difference between a testcross and a backcross?

    <p>A testcross uses a recessive homozygote as one of the parents, while a backcross does not</p> Signup and view all the answers

    What is the purpose of the first experiment in studying the principles of segregation?

    <p>To test the principles of segregation</p> Signup and view all the answers

    What is the result of crossing a heterozygote with a homozygote recessive?

    <p>Half of the offspring are heterozygous and half are homozygous recessive</p> Signup and view all the answers

    What is the purpose of backcrossing in genetics?

    <p>To separate out certain characteristics in a related group of organisms</p> Signup and view all the answers

    What is the advantage of using a testcross over a backcross?

    <p>A testcross always uses a recessive homozygote as one of the parents</p> Signup and view all the answers

    What is the principle of segregation?

    <p>The principle that each pair of alleles separates during gamete formation</p> Signup and view all the answers

    Why is a testcross useful in genetics?

    <p>Because it allows for the determination of genotypes, especially when it is unclear</p> Signup and view all the answers

    What is the result of crossing two heterozygotes?

    <p>Half of the offspring are heterozygous and half are homozygous recessive</p> Signup and view all the answers

    What is the main difference between a heterozygote and a homozygote?

    <p>A heterozygote has two different alleles, while a homozygote has two identical alleles</p> Signup and view all the answers

    Study Notes

    Historical Development of Genetics

    • Preformation theory (1665): Development is simply a matter of growth of a tiny homunculus, with two opposing views - "spermatist" and "ovist".
    • Epigenesis theory (1759): Development occurs through a series of complex interactions, with sex cells being homogenous bits of organic matter containing nothing resembling the body that will develop from them.

    Key Figures in Genetics

    • Jan Swammerdam
    • Charles Bonnet
    • Karl Ernst von Baer
    • Charles Lamarck
    • August Weismann
    • Gregor Mendel

    Principles of Segregation

    • Useful in genetics studies for determining the genotypes of individual organisms (homozygous or heterozygous)
    • Helps isolate (separate out) certain characteristics in a related group of animals or plants

    First Experiment: Testing the Principle of Segregation

    • F1 Generation: Cross between two individuals with different genotypes (e.g., Dd x dd)
    • Backcross: F1 (progeny) is mated or crossed back to one of their parents or with an individual that has a parental genotype

    Difference between Testcross and Backcross

    • Testcross: A recessive homozygote is always used as one of the parents, with a specific goal of identifying the genotype of the other parent
    • Backcross: Not necessarily true, with the goal of identifying the genotype of the F1 progeny### First Experiment: Testcross and Backcross
    • In testcross, a recessive homozygote is always used as one of the parents.
    • The testcross parent is homozygous recessive for the gene of interest.
    • This is not necessarily true in a backcross.

    Principles of Segregation

    • The results of a testcross can be mathematically expressed as two monohybrid crosses, each expected to result in a 3:1 ratio.
    • The combined result is a 9:3:3:1 ratio, which conforms to the law of probability called the "Product Rule".

    Second Experiment: Dihybrid Backcross

    • When a 9:3:3:1 ratio results in an experiment, geneticists may postulate that two independent pairs of alleles are involved.
    • One member of each pair behaves like a dominant over its allele.
    • The F1 generation is heterozygous for both genes (RrYy).
    • The gametes produced are RY, Ry, rY, and ry.
    • The resulting genotype and phenotype ratios are 1:1:1:1.

    Trihybrid Ratios

    • A cross between homozygous parents that differ in three gene pairs is a combination of three-pair crosses operating together.
    • The genotype ratio is a combination of three independent monohybrid crosses.

    Probability and Genetic Events

    • Probability is used to calculate the likelihood of genetic events.
    • The independence of genetic events is a key concept in probability calculations.
    • The binomial expansion/distribution is a mathematical formula used to calculate the probability of multiple events.
    • The formula is P = (n!/s!t!)(psqt), where n is the total number of events, s is the number of successes, t is the number of failures, p is the probability of success, and q is the probability of failure.

    Examples of Probability Calculations

    • If four babies are born at a given hospital on the same day, the probability that two will be boys and two will be girls is 10/32.
    • If a heterozygous man and woman plan to have four children, the probability that any given child will be normal is 1/2, and the probability that all four will be normal is 1/16.

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    Description

    This quiz covers the key figures and their contributions to the development of evolutionary theory, from preformation to modern genetics.

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