History of Blood Group Discovery

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Questions and Answers

What is the most important blood group system in transfusion medicine?

  • ABO (correct)
  • Lewis
  • I/i
  • P1

Where are ABO antigens found in the body?

  • Lymphocytes only
  • Lymphocytes and epithelial cells
  • Platelets and saliva
  • RBC and body fluids (correct)

Which gene must be inherited for the formation of ABO antigens in body fluids & secretions?

  • H gene (correct)
  • B gene
  • A gene
  • AB genes

What is the Bombay phenotype associated with?

<p>hh genotype (A)</p> Signup and view all the answers

What type of linkage is found in ABO antigens in body fluids & secretions?

<p>$\beta1—&gt;3$ linkage (B)</p> Signup and view all the answers

How many antigen sites does Type O blood have?

<p>~1.7 million H antigen sites (B)</p> Signup and view all the answers

What is the difference in the number of antigenic sites between A1 and A2 subgroups?

<p>1.5 million more antigenic sites in A1 subgroup (A)</p> Signup and view all the answers

Which blood group exhibits the most transferase enzyme activity according to the text?

<p>Blood Group O (B)</p> Signup and view all the answers

What is the characteristic of branched A antigens?

<p>They exhibit more transferase enzyme activity (B)</p> Signup and view all the answers

Which lectin shows a negative reaction with the Bombay phenotype?

<p>Anti-A1 lectin (Ulex europaeus) (C)</p> Signup and view all the answers

Who exhibits ABO soluble antigens based on the Se genes?

<p>Individuals with Se genes (D)</p> Signup and view all the answers

When is the maximal production of ABO antibodies observed?

<p>Around 5-10 years of age (B)</p> Signup and view all the answers

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