History of Blood Group Discovery
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Questions and Answers

What is the most important blood group system in transfusion medicine?

  • ABO (correct)
  • Lewis
  • I/i
  • P1

    • Where are ABO antigens found in the body?

  • Lymphocytes only
  • Lymphocytes and epithelial cells
  • Platelets and saliva
  • RBC and body fluids (correct)

    • Which gene must be inherited for the formation of ABO antigens in body fluids & secretions?

  • H gene (correct)
  • B gene
  • A gene
  • AB genes

    • What is the Bombay phenotype associated with?

    <p>hh genotype</p> Signup and view all the answers

    What type of linkage is found in ABO antigens in body fluids & secretions?

    <p>$\beta1—&gt;3$ linkage</p> Signup and view all the answers

    How many antigen sites does Type O blood have?

    <p>~1.7 million H antigen sites</p> Signup and view all the answers

    What is the difference in the number of antigenic sites between A1 and A2 subgroups?

    <p>1.5 million more antigenic sites in A1 subgroup</p> Signup and view all the answers

    Which blood group exhibits the most transferase enzyme activity according to the text?

    <p>Blood Group O</p> Signup and view all the answers

    What is the characteristic of branched A antigens?

    <p>They exhibit more transferase enzyme activity</p> Signup and view all the answers

    Which lectin shows a negative reaction with the Bombay phenotype?

    <p>Anti-A1 lectin (Ulex europaeus)</p> Signup and view all the answers

    Who exhibits ABO soluble antigens based on the Se genes?

    <p>Individuals with Se genes</p> Signup and view all the answers

    When is the maximal production of ABO antibodies observed?

    <p>Around 5-10 years of age</p> Signup and view all the answers

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