12 Questions
What is the most important blood group system in transfusion medicine?
ABO
Where are ABO antigens found in the body?
RBC and body fluids
Which gene must be inherited for the formation of ABO antigens in body fluids & secretions?
H gene
What is the Bombay phenotype associated with?
hh genotype
What type of linkage is found in ABO antigens in body fluids & secretions?
$\beta1—>3$ linkage
How many antigen sites does Type O blood have?
~1.7 million H antigen sites
What is the difference in the number of antigenic sites between A1 and A2 subgroups?
1.5 million more antigenic sites in A1 subgroup
Which blood group exhibits the most transferase enzyme activity according to the text?
Blood Group O
What is the characteristic of branched A antigens?
They exhibit more transferase enzyme activity
Which lectin shows a negative reaction with the Bombay phenotype?
Anti-A1 lectin (Ulex europaeus)
Who exhibits ABO soluble antigens based on the Se genes?
Individuals with Se genes
When is the maximal production of ABO antibodies observed?
Around 5-10 years of age
Explore the historical perspective behind Karl Landsteiner's discovery of the ABO blood group system in 1900 and its significance in transfusion medicine. Learn about the risks of ABO-incompatible blood transfusions and the genetics involved.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
