Histocytes Overview and Structure
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Histocytes Overview and Structure

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Questions and Answers

What type of cells are described as small irregular branching, star-shaped cells?

  • Blood cells
  • Neurons
  • Bone cells
  • Pericytes (correct)
  • Bone marrow is responsible for the production of blood cells.

    True

    What are the primary functions of pericytes?

    Support and regulate blood vessel function

    What type of cell is formed when histocytes fuse together?

    <p>Foreign body giant cell</p> Signup and view all the answers

    Pericytes are located around _____ vessels.

    <p>blood</p> Signup and view all the answers

    Match the following terms with their descriptions:

    <p>Bone marrow = Production of blood cells Pericytes = Cells supporting blood vessels Blood cells = Cells responsible for transporting oxygen LM = Light microscopy technique</p> Signup and view all the answers

    Foreign body giant cells are responsible for engulfing small foreign bodies.

    <p>False</p> Signup and view all the answers

    What is the function of foreign body giant cells?

    <p>To engulf large foreign bodies.</p> Signup and view all the answers

    Histocytes, when fused together, form multinucleated cells known as _______.

    <p>foreign body giant cells</p> Signup and view all the answers

    Match the following terms with their descriptions:

    <p>Histiocytes = Type of immune cell that can fuse to form giant cells Multinucleated cells = Cells with multiple nuclei typically formed by fusion Foreign body giant cells = Specialized cells that engulf large foreign bodies Engulfing = The process of internalizing particles or cells</p> Signup and view all the answers

    Which type of cells are found in the skin and are responsible for immune responses?

    <p>Langerhan's cells</p> Signup and view all the answers

    Microglia cells are found in the kidney.

    <p>False</p> Signup and view all the answers

    What type of cells have the same structure and function as fixed cells?

    <p>Mesengial cells</p> Signup and view all the answers

    In the central nervous system, there are __________ cells.

    <p>microglia</p> Signup and view all the answers

    Match the following locations with their corresponding cell types:

    <p>CNS = Microglia cells Skin = Langerhan's cells Kidney = Mesengial cells</p> Signup and view all the answers

    What characteristic features do secretory cells display?

    <p>Well-developed rough endoplasmic reticulum</p> Signup and view all the answers

    The nucleus in secretory cells is large and easily visible.

    <p>False</p> Signup and view all the answers

    Name one organelle found in secretory cells.

    <p>Golgi apparatus</p> Signup and view all the answers

    Secretory granules are described as __________ or hidden.

    <p>masked</p> Signup and view all the answers

    Match the organelles with their functions:

    <p>Mitochondria = Energy production Rough Endoplasmic Reticulum = Protein synthesis Golgi Apparatus = Packaging of proteins Secretory Granules = Storage of secreted substances</p> Signup and view all the answers

    What staining method is used to visualize reticular fibers?

    <p>Gomori’s reticulin stain</p> Signup and view all the answers

    Reticular fibers can be stained using H&E methods.

    <p>False</p> Signup and view all the answers

    What is another term for reticular fibers based on their staining properties?

    <p>argyrophilic or argentaffin fibers</p> Signup and view all the answers

    Reticular fibers can be stained black by using _____ impregnation methods.

    <p>silver</p> Signup and view all the answers

    Match the following terms related to reticular fibers:

    <p>Gomori’s reticulin stain = Specific stain for reticular fibers Argyrophilic = Staining affinity for silver Silver impregnation methods = Methods for visualizing reticular fibers H&amp;E stain = Common stain not used for reticular fibers</p> Signup and view all the answers

    Study Notes

    Histocytes

    • Histocytes can fuse to form multinucleated cells called foreign body giant cells
    • These cells engulf large foreign bodies.
    • They are also known as phagocytes.
    • They are found in various tissues, including the CNS, skin, and kidneys.
    • In the CNS, they are called mesoglia cells or microglia cells
    • In the skin, they are called Langerhans cells.
    • In the kidneys, they are called mesangial cells.

    Structure of Histocytes

    • LM:
      • Small, irregular, branching, star-shaped cells.
      • The nucleus is small, eccentric, and often masked by granules.
    • EM:
      • Have features of secretory cells, including well-developed RER, mitochondria, Golgi apparatus, and electron-dense membrane-bound secretory granules.
    • LM Staining:
      • Not stained with H&E stain.
      • Specifically stained black by silver impregnation methods (Gomori’s reticulin stain).
      • Reticular fibers are called argyrophilic or argentaffin fibers.

    Location

    • Bone marrow (where blood cells are produced).
    • Around blood vessels as pericytes.

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    Description

    This quiz covers the characteristics and functions of histocytes, including their capability to form multinucleated giant cells and their subclasses in various tissues. You will learn about their structure through light and electron microscopy, as well as their staining properties. Ideal for students studying cellular biology or histology.

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