Histamine and Allergic Rhinitis in Minor Illness
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Questions and Answers

What is the primary mechanism by which histamine is released from mast cells?

  • Adrenergic receptor activation
  • Calcium-channel blockers
  • Phospholipase C mechanism (correct)
  • Phospholipase A mechanism

    • What is the primary effect of histamine on blood vessels?

  • Vasodilation (correct)
  • Vasoconstriction
  • Decreased blood flow
  • Increased blood pressure

    • Which of the following is a treatment option for preventing histamine release?

  • Antihistamines
  • Mast cell stabilisers (correct)
  • Corticosteroids
  • α-adrenoceptor agonists

    • What is the primary effect of histamine on nerves?

    <p>Itchiness</p> Signup and view all the answers

    What is the primary mechanism by which α-adrenoceptor agonists work to counteract the effects of histamine?

    <p>Physiologically opposing histamine action</p> Signup and view all the answers

    What is the primary reason for the rapid metabolism of histamine?

    <p>To ensure local action and prevent systemic effects</p> Signup and view all the answers

    What is the primary mechanism of histamine release from mast cells?

    <p>Degranulation of mast cells through IgE-mediated signaling</p> Signup and view all the answers

    What is the result of histamine's cellular effects on the nasal passages in allergic rhinitis?

    <p>Increased mucus production and vasodilation</p> Signup and view all the answers

    What are the two primary enzymes involved in histamine metabolism?

    <p>Diamine oxidase and Histamine-N-methyltransferase</p> Signup and view all the answers

    What is the name of the autocoid that is rapidly metabolized to ensure local action?

    <p>Histamine</p> Signup and view all the answers

    What is the primary purpose of histamine release in allergic reactions?

    <p>To initiate a rapid immune response</p> Signup and view all the answers

    What is the role of α adrenoreceptor agonists in counteracting histamine-induced effects?

    <p>They cause vasoconstriction to counteract histamine-induced vasodilation</p> Signup and view all the answers

    What is the primary mechanism by which histamine is released during an allergic response?

    <p>IgE antibodies bind to mast cells, triggering histamine release</p> Signup and view all the answers

    What is the primary effect of histamine on blood vessels?

    <p>Vasodilation and increase in vascular permeability</p> Signup and view all the answers

    What is the purpose of leukotriene receptor antagonists in treating allergic rhinitis?

    <p>To antagonize the action of leukotrienes on airway smooth muscle</p> Signup and view all the answers

    What is the primary role of histamine in the allergic response?

    <p>To mediate the allergic response through H1 receptors</p> Signup and view all the answers

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