High Altitude Effects on Humans

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What are the physiological responses to high altitude?

Physiological responses to high altitude include hyperventilation, polycythemia, increased capillary density in muscle, and hypoxic pulmonary vasoconstriction–increased intracellular oxidative enzymes.

What are the three altitude regions recognized by mountain medicine?

The three altitude regions recognized by mountain medicine are high altitude (1,500–3,500 metres), very high altitude (3,500–5,500 metres), and extreme altitude (above 5,500 metres).

What are the potential medical problems associated with travel to high altitude regions?

Medical problems associated with travel to high altitude regions range from mild symptoms of acute mountain sickness to potentially fatal conditions like high-altitude pulmonary edema (HAPE) and high-altitude cerebral edema (HACE).

What is the physiological impact of decreased atmospheric pressure with increasing altitude?

As atmospheric pressure decreases with increasing altitude, the partial pressure of oxygen (pO2) also decreases, leading to altitude acclimatization in the body.

How do Tibetans and Andeans differ in their adaptation to high altitude?

Tibetans and Andeans are two groups relatively well adapted to high altitude, but they display noticeably different phenotypes.

Explore the medical problems and physiological effects associated with high altitude, including reduced oxygen levels and lower ambient temperatures. Understand how these factors impact human health at high altitudes.

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