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Heterotrimeric G Protein Receptor Signaling Pathway

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Heterotrimeric G Protein Receptor Signaling Pathway

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Questions and Answers

Which protein is responsible for carrying the stimulus for apoptosis in the extrinsic pathway?

Tumor necrosis factor (TNF) (correct)

Bcl-2

Procaspase

Cytochrome c

What is the role of procaspases in the extrinsic pathway of apoptosis?

To detect TNF

To regulate the intrinsic pathway

To convert other procaspases to caspases (correct)

To activate executioner caspases

Which type of proteins can stimulate mitochondria to leak proteins in the intrinsic pathway?

Antiapoptotic members of the Bcl-2 family

Proapoptotic members of the Bcl-2 family (correct)

Caspases

BH3-only proteins

What is the role of the TNF receptor in the extrinsic pathway of apoptosis?

To detect TNF Signup and view all the answers

Which of the following proteins is NOT a member of the Bcl-2 family?

TNF Signup and view all the answers

What is the outcome of the activation of the extrinsic pathway of apoptosis?

Apoptosis Signup and view all the answers

Which of the following is a characteristic of the intrinsic pathway of apoptosis?

Is regulated by Bcl-2 family members Signup and view all the answers

What is the function of BH3-only proteins in the intrinsic pathway of apoptosis?

To promote apoptosis by an indirect mechanism Signup and view all the answers

What is the outcome of the activation of caspases in the extrinsic pathway of apoptosis?

Apoptosis Signup and view all the answers

Which type of stimuli triggers apoptosis by the intrinsic pathway?

Internal stimuli Signup and view all the answers