Hemostasis and Coagulation in Hematology

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Which factor is also known as Proconvertin?

Factor VIII

Factor VII (correct)

Factor X

Factor IX

According to Howell's Theory, what did he identify as the hypothetical inhibitor antiprothrombin?

Phospholipid (correct)

Von Willebrand factor

Fibrinogen

Vitamin K

Which factor is NOT part of the Thrombin Sensitive Group?

Factor XII

Factor IX (correct)

Factor V

Factor I

Which factor does NOT depend on Vitamin K?

Factor VIII (C) Signup and view all the answers

Which factor is known as the Hageman factor?

Factor XII (A) Signup and view all the answers

Which factor is present in BOTH serum and plasma?

Factor II (A) Signup and view all the answers

What is the primary function of the vascular intima when it is damaged?

Promote coagulation (A) Signup and view all the answers

What is the role of von Willebrand factor in platelet adhesion?

It is necessary for platelet adhesion (D) Signup and view all the answers

Which of the following is a characteristic of secondary hemostasis?

Activation of clotting factors (A) Signup and view all the answers

What is the relationship between coagulation and fibrinolysis according to the passage?

Coagulation and fibrinolysis should be equal (B) Signup and view all the answers

Which of the following is a function of P-selectin, ICAMs, and PECAMs on the vascular intima?

They activate tissue factor (A) Signup and view all the answers

What is the role of plasminogen activator inhibitor-1 (PAI-1) in fibrinolysis?

It inhibits tissue plasminogen activator (C) Signup and view all the answers

What is the role of von Willebrand factor in primary hemostasis?

Acts as a bridge between collagen and platelets (B) Signup and view all the answers

What distinguishes secondary hemostasis from primary hemostasis?

Involves platelets and the coagulation system (C) Signup and view all the answers

What is the significance of tissue factor in secondary hemostasis?

Facilitates the initiation of the coagulation cascade (B) Signup and view all the answers

What are zymogens in the context of hemostasis?

Inactive forms of clotting factors (C) Signup and view all the answers

Which blood cells add structural integrity to the fibrin clot?

Red blood cells (B) Signup and view all the answers

What role do platelets play in primary hemostasis?

Form a plug to stop bleeding (D) Signup and view all the answers

What is the primary function of vasoconstriction in hemostasis?

To facilitate blood clot formation (A) Signup and view all the answers

Which factor contributes to the formation of a visible coagulum during coagulation?

Platelet aggregation (D) Signup and view all the answers

What is the role of endothelial cells in maintaining vascular integrity?

Forming a smooth surface that prevents turbulence (A) Signup and view all the answers

Which molecule secreted by intact endothelium acts as an anticoagulant?

Nitric oxide (B) Signup and view all the answers

What is the main purpose of the fibrinolytic process in hemostasis?

Remove excess hemostatic material (D) Signup and view all the answers

Which factor ensures a hemostatic balance according to the provided text?

Anticoagulant properties of intact endothelium (B) Signup and view all the answers

What is the role of Factor XIIA in the coagulation cascade?

Activates Factor XI to Factor XIA (B) Signup and view all the answers

Which factor serves as a catalyst for turning Factor X into Factor XA?

Factor IXA (A) Signup and view all the answers

When is endothelial collagen exposed in the coagulation cascade?

When endothelial damage occurs (C) Signup and view all the answers

Which factor is activated by Tissue Factor in the extrinsic pathway?

Factor VII (C) Signup and view all the answers

In the coagulation cascade, what is the final stage of hemostasis known as?

Fibrinolysis (B) Signup and view all the answers

Which factor has a greater concentration in the blood, Factor IX or Factor XI?

Factor IX (D) Signup and view all the answers