Hemostasis and Coagulation in Hematology
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Questions and Answers

Which factor is also known as Proconvertin?

  • Factor VIII
  • Factor VII (correct)
  • Factor X
  • Factor IX
  • According to Howell's Theory, what did he identify as the hypothetical inhibitor antiprothrombin?

  • Phospholipid (correct)
  • Von Willebrand factor
  • Fibrinogen
  • Vitamin K
  • Which factor is NOT part of the Thrombin Sensitive Group?

  • Factor XII
  • Factor IX (correct)
  • Factor V
  • Factor I
  • Which factor does NOT depend on Vitamin K?

    <p>Factor VIII</p> Signup and view all the answers

    Which factor is known as the Hageman factor?

    <p>Factor XII</p> Signup and view all the answers

    Which factor is present in BOTH serum and plasma?

    <p>Factor II</p> Signup and view all the answers

    What is the primary function of the vascular intima when it is damaged?

    <p>Promote coagulation</p> Signup and view all the answers

    What is the role of von Willebrand factor in platelet adhesion?

    <p>It is necessary for platelet adhesion</p> Signup and view all the answers

    Which of the following is a characteristic of secondary hemostasis?

    <p>Activation of clotting factors</p> Signup and view all the answers

    What is the relationship between coagulation and fibrinolysis according to the passage?

    <p>Coagulation and fibrinolysis should be equal</p> Signup and view all the answers

    Which of the following is a function of P-selectin, ICAMs, and PECAMs on the vascular intima?

    <p>They activate tissue factor</p> Signup and view all the answers

    What is the role of plasminogen activator inhibitor-1 (PAI-1) in fibrinolysis?

    <p>It inhibits tissue plasminogen activator</p> Signup and view all the answers

    What is the role of von Willebrand factor in primary hemostasis?

    <p>Acts as a bridge between collagen and platelets</p> Signup and view all the answers

    What distinguishes secondary hemostasis from primary hemostasis?

    <p>Involves platelets and the coagulation system</p> Signup and view all the answers

    What is the significance of tissue factor in secondary hemostasis?

    <p>Facilitates the initiation of the coagulation cascade</p> Signup and view all the answers

    What are zymogens in the context of hemostasis?

    <p>Inactive forms of clotting factors</p> Signup and view all the answers

    Which blood cells add structural integrity to the fibrin clot?

    <p>Red blood cells</p> Signup and view all the answers

    What role do platelets play in primary hemostasis?

    <p>Form a plug to stop bleeding</p> Signup and view all the answers

    What is the primary function of vasoconstriction in hemostasis?

    <p>To facilitate blood clot formation</p> Signup and view all the answers

    Which factor contributes to the formation of a visible coagulum during coagulation?

    <p>Platelet aggregation</p> Signup and view all the answers

    What is the role of endothelial cells in maintaining vascular integrity?

    <p>Forming a smooth surface that prevents turbulence</p> Signup and view all the answers

    Which molecule secreted by intact endothelium acts as an anticoagulant?

    <p>Nitric oxide</p> Signup and view all the answers

    What is the main purpose of the fibrinolytic process in hemostasis?

    <p>Remove excess hemostatic material</p> Signup and view all the answers

    Which factor ensures a hemostatic balance according to the provided text?

    <p>Anticoagulant properties of intact endothelium</p> Signup and view all the answers

    What is the role of Factor XIIA in the coagulation cascade?

    <p>Activates Factor XI to Factor XIA</p> Signup and view all the answers

    Which factor serves as a catalyst for turning Factor X into Factor XA?

    <p>Factor IXA</p> Signup and view all the answers

    When is endothelial collagen exposed in the coagulation cascade?

    <p>When endothelial damage occurs</p> Signup and view all the answers

    Which factor is activated by Tissue Factor in the extrinsic pathway?

    <p>Factor VII</p> Signup and view all the answers

    In the coagulation cascade, what is the final stage of hemostasis known as?

    <p>Fibrinolysis</p> Signup and view all the answers

    Which factor has a greater concentration in the blood, Factor IX or Factor XI?

    <p>Factor IX</p> Signup and view all the answers

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