Hemostasis and Coagulation in Hematology

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Questions and Answers

Which factor is also known as Proconvertin?

  • Factor VIII
  • Factor VII (correct)
  • Factor X
  • Factor IX

According to Howell's Theory, what did he identify as the hypothetical inhibitor antiprothrombin?

  • Phospholipid (correct)
  • Von Willebrand factor
  • Fibrinogen
  • Vitamin K

Which factor is NOT part of the Thrombin Sensitive Group?

  • Factor XII
  • Factor IX (correct)
  • Factor V
  • Factor I

Which factor does NOT depend on Vitamin K?

<p>Factor VIII (C)</p> Signup and view all the answers

Which factor is known as the Hageman factor?

<p>Factor XII (A)</p> Signup and view all the answers

Which factor is present in BOTH serum and plasma?

<p>Factor II (A)</p> Signup and view all the answers

What is the primary function of the vascular intima when it is damaged?

<p>Promote coagulation (A)</p> Signup and view all the answers

What is the role of von Willebrand factor in platelet adhesion?

<p>It is necessary for platelet adhesion (D)</p> Signup and view all the answers

Which of the following is a characteristic of secondary hemostasis?

<p>Activation of clotting factors (A)</p> Signup and view all the answers

What is the relationship between coagulation and fibrinolysis according to the passage?

<p>Coagulation and fibrinolysis should be equal (B)</p> Signup and view all the answers

Which of the following is a function of P-selectin, ICAMs, and PECAMs on the vascular intima?

<p>They activate tissue factor (A)</p> Signup and view all the answers

What is the role of plasminogen activator inhibitor-1 (PAI-1) in fibrinolysis?

<p>It inhibits tissue plasminogen activator (C)</p> Signup and view all the answers

What is the role of von Willebrand factor in primary hemostasis?

<p>Acts as a bridge between collagen and platelets (B)</p> Signup and view all the answers

What distinguishes secondary hemostasis from primary hemostasis?

<p>Involves platelets and the coagulation system (C)</p> Signup and view all the answers

What is the significance of tissue factor in secondary hemostasis?

<p>Facilitates the initiation of the coagulation cascade (B)</p> Signup and view all the answers

What are zymogens in the context of hemostasis?

<p>Inactive forms of clotting factors (C)</p> Signup and view all the answers

Which blood cells add structural integrity to the fibrin clot?

<p>Red blood cells (B)</p> Signup and view all the answers

What role do platelets play in primary hemostasis?

<p>Form a plug to stop bleeding (D)</p> Signup and view all the answers

What is the primary function of vasoconstriction in hemostasis?

<p>To facilitate blood clot formation (A)</p> Signup and view all the answers

Which factor contributes to the formation of a visible coagulum during coagulation?

<p>Platelet aggregation (D)</p> Signup and view all the answers

What is the role of endothelial cells in maintaining vascular integrity?

<p>Forming a smooth surface that prevents turbulence (A)</p> Signup and view all the answers

Which molecule secreted by intact endothelium acts as an anticoagulant?

<p>Nitric oxide (B)</p> Signup and view all the answers

What is the main purpose of the fibrinolytic process in hemostasis?

<p>Remove excess hemostatic material (D)</p> Signup and view all the answers

Which factor ensures a hemostatic balance according to the provided text?

<p>Anticoagulant properties of intact endothelium (B)</p> Signup and view all the answers

What is the role of Factor XIIA in the coagulation cascade?

<p>Activates Factor XI to Factor XIA (B)</p> Signup and view all the answers

Which factor serves as a catalyst for turning Factor X into Factor XA?

<p>Factor IXA (A)</p> Signup and view all the answers

When is endothelial collagen exposed in the coagulation cascade?

<p>When endothelial damage occurs (C)</p> Signup and view all the answers

Which factor is activated by Tissue Factor in the extrinsic pathway?

<p>Factor VII (C)</p> Signup and view all the answers

In the coagulation cascade, what is the final stage of hemostasis known as?

<p>Fibrinolysis (B)</p> Signup and view all the answers

Which factor has a greater concentration in the blood, Factor IX or Factor XI?

<p>Factor IX (D)</p> Signup and view all the answers

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