Hemolytic Disease of the Newborn and Thrombocytes Quiz
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Questions and Answers

What is the primary difference between arterial thrombus and venous thrombus?

  • Arterial thrombus contains fewer platelets and fibrin, while venous thrombus has fewer RBCs.
  • Arterial thrombus has more RBCs and fibrin, while venous thrombus has more platelets.
  • Arterial thrombus has more platelets and fibrin, while venous thrombus has fewer RBCs. (correct)
  • Arterial thrombus contains fewer platelets and fibrin, while venous thrombus has more RBCs.

    • Where does a venous thrombus commonly cause an embolism?

  • Brain
  • Lungs (correct)
  • Kidneys
  • Heart

    • Which part of Virchow's triad refers to the blood's tendency to clot excessively?

  • Hypercoagulability (correct)
  • Hemodynamic changes
  • Endothelial dysfunction
  • All of the above

    • Which coagulation pathway does PT measure?

    <p>Extrinsic pathway</p> Signup and view all the answers

    How does coumadin exert its anticoagulant effect?

    <p>Inhibits vitamin K</p> Signup and view all the answers

    What does INR measure in relation to anticoagulation therapy?

    <p>Clot formation time</p> Signup and view all the answers

    What is the primary function of heparin in the context of coagulation?

    <p>Increases antithrombin III activity</p> Signup and view all the answers

    Why is it important to measure PT and PTT in patients with suspected clotting disorders?

    <p>To identify abnormalities in the coagulation cascade pathways</p> Signup and view all the answers

    'Hypercoagulability' in Virchow's triad refers to:

    <p>Increased tendency for blood clotting</p> Signup and view all the answers

    'Endothelial dysfunction' in Virchow's triad relates to:

    <p>Decreased nitric oxide production</p> Signup and view all the answers

    What is the role of plasmin in fibrinolysis?

    <p>Break down fibrin units after clot formation</p> Signup and view all the answers

    Which of the following is a cause of hypercoagulation?

    <p>Predisposition for clots</p> Signup and view all the answers

    What can cause inappropriate thrombosis according to the text?

    <p>Venous thrombus with more fibrin and RBCs</p> Signup and view all the answers

    What is the primary function of tissue plasminogen activator (TPA)?

    <p>Break down clots</p> Signup and view all the answers

    What is the cause of hypocoagulation according to the provided text?

    <p>Poor platelet function</p> Signup and view all the answers

    What is the main difference between extrinsic and intrinsic coagulation pathways?

    <p>Extrinsic pathway involves factors released by damaged tissues, while intrinsic pathway involves factors released when exposed to collagen and damaged endothelium</p> Signup and view all the answers

    What is the role of vitamin K in the coagulation pathways?

    <p>Vitamin K activates factors 2, 7, 9, and 10 in the coagulation cascade</p> Signup and view all the answers

    Where are most of the coagulation factors produced?

    <p>Liver</p> Signup and view all the answers

    Describe the role of proteins C in the coagulation cascade.

    <p>Proteins C inactivate factors Xa and thrombin</p> Signup and view all the answers

    Which molecule is activated by thrombin in the context of clot dissolution?

    <p>Plasminogen</p> Signup and view all the answers

    What is the main role of erythropoietin in the regulation of erythropoiesis?

    <p>Stimulating red bone marrow production of RBCs</p> Signup and view all the answers

    Which of the following correctly describes the distribution of bone marrow as we age?

    <p>Red bone marrow is replaced by yellow bone marrow as we age</p> Signup and view all the answers

    What can tumors cause in relation to erythrocyte production?

    <p>Increased bone marrow leading to high reticulocytes</p> Signup and view all the answers

    What is the primary function of RhoGAM in preventing HDN?

    <p>Inhibiting the mother's immune system from attacking fetal RBCs</p> Signup and view all the answers

    Which blood type is considered the universal donor?

    <p>Type O</p> Signup and view all the answers

    What is the primary role of thromboxane A2 (TxA2) and serotonin (5HT) in hemostasis?

    <p>Promote vasoconstriction</p> Signup and view all the answers

    What determines the presence of antigens on the surface of red blood cells?

    <p>Agglutinogens present on the RBC surface</p> Signup and view all the answers

    Which component binds collagen in plasma and glycoprotein 1b to bridge platelets and damaged vessels during platelet plug formation?

    <p>Von Willebrand factor (vWF)</p> Signup and view all the answers

    What is the main function of the platelet phospholipid membrane in the coagulation mechanism?

    <p>Serve as a site for enzymatic reactions</p> Signup and view all the answers

    What is the role of procoagulants (clotting factors) in hemostasis?

    <p>Participate in the coagulation process</p> Signup and view all the answers

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