10 Questions
What is the most common cause for Hemolytic Disease of the Newborn (HDFN) occurring in the first pregnancy?
Feto-maternal hemorrhage
In HDFN, what conditions need to occur simultaneously for the condition to manifest?
Mother has a 37ºC active IgG red cell alloantibody and the corresponding antigen is present on the fetal red cells
What is the mechanism of HDFN?
Fetus inherits blood group antigens from the father that are foreign to the mother, leading to feto-maternal hemorrhage
How can maternal antibody production be stimulated?
Feto-maternal hemorrhage and previous pregnancies
What can cause FMH, leading to the stimulation of maternal antibody production?
Still births and abortions
Maternal antibody production can be stimulated only through previous pregnancies.
False
Fetal red cells carrying paternally derived antigens can be destroyed in the maternal circulation.
False
Still births and abortions do not cause fetomaternal hemorrhage (FMH).
False
Hemolytic Disease of the Newborn (HDFN) can occur in the first pregnancy even if the mother does not have a 37ºC active IgG red cell alloantibody.
False
HDFN occurs if the fetus inherits blood group antigens from the father that are foreign to the mother.
True
Test your knowledge of Hemolytic Disease of the Fetus and Newborn (HDFN) with this quiz. Explore the definition and mechanism of HDFN, maternal antibody production, clinical signs, factors influencing severity, different antibody specificities, and laboratory testing.
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