Podcast
Questions and Answers
Heme is converted to bilirubin in _______.
Heme is converted to bilirubin in _______.
- erythrocytes
- macrophages (correct)
- hepatocytes
- kidney cells
Which of the following designations represents HbF?
Which of the following designations represents HbF?
- $\alpha2\gamma2$ (correct)
- $\alpha2\beta2$
- $\delta2\beta2$
- $\alpha2\delta2$
Beta Thalasemia normally 2 beta globin chains bind to chromosome 11. How many deficient betas are present in β-thalasemia major?
Beta Thalasemia normally 2 beta globin chains bind to chromosome 11. How many deficient betas are present in β-thalasemia major?
- Four
- One
- Three
- Two (correct)
Which condition results in excess absorption of iron due to a genetic disorder?
Which condition results in excess absorption of iron due to a genetic disorder?
What is the cause of sickle cell disease?
What is the cause of sickle cell disease?
What is the composition of adult Hb A?
What is the composition of adult Hb A?
What is the manifestation of three deficient alpha globin chains in Alpha Thalasemia?
What is the manifestation of three deficient alpha globin chains in Alpha Thalasemia?
What causes sickle cell disease to be more severe?
What causes sickle cell disease to be more severe?
Excess unconjugated bilirubin in blood can diffuse to the basal ganglia causing toxic encephalopathy in which condition?
Excess unconjugated bilirubin in blood can diffuse to the basal ganglia causing toxic encephalopathy in which condition?
What is the cause of prolonged bile duct obstructions?
What is the cause of prolonged bile duct obstructions?
Which condition is characterized by reduced uptake of unconjugated bilirubin from circulation?
Which condition is characterized by reduced uptake of unconjugated bilirubin from circulation?
Which organ does ferritin/iron go to for storage in the blood circulation process?
Which organ does ferritin/iron go to for storage in the blood circulation process?
What is the main source of heme in the breakdown of hemoglobin?
What is the main source of heme in the breakdown of hemoglobin?
What is the end product of heme degradation via heme oxygenase?
What is the end product of heme degradation via heme oxygenase?
What causes jaundice due to hemolysis?
What causes jaundice due to hemolysis?
What is the classification of jaundice with normal feces and urine?
What is the classification of jaundice with normal feces and urine?
What causes yellow skin and sclerae in jaundice?
What causes yellow skin and sclerae in jaundice?
What is the end product of biliverdin via biliverdin reductase?
What is the end product of biliverdin via biliverdin reductase?
What is the cause of jaundice with excretion of bilirubin due to liver damage?
What is the cause of jaundice with excretion of bilirubin due to liver damage?
What is the primary function of macrophages in the breakdown of hemoglobin?
What is the primary function of macrophages in the breakdown of hemoglobin?
What causes jaundice due to excretion of bilirubin?
What causes jaundice due to excretion of bilirubin?
What is the consequence of bile duct obstruction in jaundice?
What is the consequence of bile duct obstruction in jaundice?
What is the cause of jaundice due to liver damage?
What is the cause of jaundice due to liver damage?
