Układ pokarmowy cz 3

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Questions and Answers

What is the result of the body absorbing too much iron from food in hemochromatosis?

  • Reduced iron levels in the blood
  • Decreased oxygen transport to tissues
  • Increased hemoglobin production in red blood cells
  • Elevated iron levels in the blood and poisoning of tissues (correct)

What is the significance of the root '-chromat-' in the term hemochromatosis?

  • It refers to the darkening of the skin due to iron deposition (correct)
  • It refers to the production of hemoglobin
  • It refers to the binding of iron to oxygen
  • It refers to the absence of color in the skin

What is the function of the iron molecule in hemoglobin proteins?

  • It produces energy in the cells
  • It binds to oxygen (correct)
  • It transports oxygen to the tissues
  • It regulates iron absorption in the body

How much iron do healthy individuals typically absorb from their diet daily?

<p>1-2 mg (C)</p> Signup and view all the answers

What is the consequence of having hemochromatosis?

<p>The body absorbs an unusually high amount of iron (C)</p> Signup and view all the answers

Why is iron essential for the body?

<p>It is necessary for oxygen transport (D)</p> Signup and view all the answers

What happens to the iron absorbed by the enterocytes in people with the C282Y mutation?

<p>It's absorbed into the bloodstream without regulation (B)</p> Signup and view all the answers

What is the main complication of hemosiderosis in the liver?

<p>Cirrhosis (C)</p> Signup and view all the answers

What is the purpose of the enterocytes in the small intestine?

<p>To regulate iron absorption (B)</p> Signup and view all the answers

What is the result of the Fenton reaction in the body?

<p>Free radical generation (A)</p> Signup and view all the answers

What is the function of the HFE gene?

<p>To control iron absorption (B)</p> Signup and view all the answers

What is the name of the disorder caused by the HFE gene mutation?

<p>Primary hemochromatosis (D)</p> Signup and view all the answers

What is the effect of frequent blood transfusions on iron levels?

<p>Increased iron levels (D)</p> Signup and view all the answers

What is the result of iron deposition in pancreatic cells?

<p>Type 1 diabetes mellitus (B)</p> Signup and view all the answers

What is the estimated amount of excess iron in the body by age 40?

<p>&gt;20 g (D)</p> Signup and view all the answers

What is the average age of diagnosis for men with hemochromatosis?

<p>50 (D)</p> Signup and view all the answers

What is the result of iron accumulation in the skin?

<p>Bronze pigmented skin (A)</p> Signup and view all the answers

What is the role of transferrin in the blood?

<p>Stores up to two iron molecules and safely transports it in the blood (C)</p> Signup and view all the answers

What is the significance of high transferrin percent saturation?

<p>The body has enough iron and doesn't need to transport it (D)</p> Signup and view all the answers

What is the purpose of the total iron binding capacity lab test?

<p>To measure the ability of the blood to carry more iron (B)</p> Signup and view all the answers

What is the function of ferritin in the body?

<p>Stores iron inside cells (B)</p> Signup and view all the answers

What is the significance of a liver biopsy in diagnosing hemochromatosis?

<p>To confirm iron deposition in the hepatocytes (D)</p> Signup and view all the answers

What is the purpose of the Prussian blue stain in diagnosing hemochromatosis?

<p>To confirm iron deposition in the liver cells (A)</p> Signup and view all the answers

What is the goal of treatment of hemochromatosis?

<p>To decrease the iron load in the body (D)</p> Signup and view all the answers

What is the mechanism of action of deferoxamine in treating hemochromatosis?

<p>Binds to free iron in the blood and makes it easier to get rid of via the urine (C)</p> Signup and view all the answers

What is the cause of hemochromatosis?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary function of the pancreatic digestive enzymes secreted into the duodenum?

<p>To aid in the digestion of food in the small intestine (B)</p> Signup and view all the answers

What is the purpose of proenzymes in the pancreas?

<p>To protect the pancreas from autodigestion by digestive enzymes (C)</p> Signup and view all the answers

What is the location of the pancreas in the body?

<p>In the upper abdomen, behind the stomach (D)</p> Signup and view all the answers

What is the term for the process of the pancreas being destroyed by its own digestive enzymes?

<p>Autodigestion (B)</p> Signup and view all the answers

What is the purpose of protease inhibitors in the pancreas?

<p>To prevent enzymes from doing damage if they become prematurely active (A)</p> Signup and view all the answers

What is the primary function of the acinar cells in the pancreas?

<p>To manufacture inactive forms of digestive enzymes (B)</p> Signup and view all the answers

What is the primary function of trypsin in the small intestine?

<p>To break down proteins into smaller peptides (D)</p> Signup and view all the answers

What is the consequence of premature activation of trypsinogen in the pancreas?

<p>Autodigestion of the pancreas and acute pancreatitis (C)</p> Signup and view all the answers

What is the primary mechanism by which alcohol abuse contributes to acute pancreatitis?

<p>Formation of a protein plug in the pancreatic duct (D)</p> Signup and view all the answers

What is the significance of the duodenum in the activation of trypsinogen?

<p>It is the site of trypsinogen activation by enteropeptidase (D)</p> Signup and view all the answers

What is the mnemonic device used to remember the causes of acute pancreatitis?

<p>I GET SMASHED (C)</p> Signup and view all the answers

What is the result of autodigestion of the pancreas in acute pancreatitis?

<p>Liquefactive hemorrhagic necrosis of the pancreas (A)</p> Signup and view all the answers

What is the role of neutrophils in the progression of acute pancreatitis?

<p>To release reactive oxygen species and proteases (C)</p> Signup and view all the answers

What is the effect of gallstones on the pancreatic duct?

<p>They block the release of pancreatic juices (A)</p> Signup and view all the answers

What is the consequence of oxidative metabolism of alcohol in the pancreas?

<p>Production of reactive oxygen species (C)</p> Signup and view all the answers

What is the result of pancreatic tissue destruction in acute pancreatitis?

<p>Liquefactive hemorrhagic necrosis of the pancreas (A)</p> Signup and view all the answers

What is the main characteristic of a pancreatic pseudocyst?

<p>Fibrous tissue surrounding liquefactive necrotic tissue (D)</p> Signup and view all the answers

What is the most common complication of pancreatic pseudocysts?

<p>Infection by E.coli (B)</p> Signup and view all the answers

What is the best way to image a pancreatic pseudocyst?

<p>Abdominal CT scan (D)</p> Signup and view all the answers

What is the leading cause of death among individuals with acute pancreatitis?

<p>Acute respiratory distress syndrome (C)</p> Signup and view all the answers

What is a distinctive sign of acute pancreatitis?

<p>Hypocalcemia (D)</p> Signup and view all the answers

What is the significance of Cullen's sign in acute pancreatitis?

<p>Indicates necrosis induced hemorrhaging (C)</p> Signup and view all the answers

What is the goal of treatment for acute pancreatitis?

<p>To control pain and provide fluids (C)</p> Signup and view all the answers

What is the significance of lipase in diagnosing acute pancreatitis?

<p>It is a specific enzyme for pancreatitis (D)</p> Signup and view all the answers

What is the complication of acute pancreatitis that can cause leaky blood vessels throughout the body?

<p>Acute respiratory distress syndrome (B)</p> Signup and view all the answers

What is the significance of a high white blood cell count in pancreatic pseudocysts?

<p>Indicates infection (B)</p> Signup and view all the answers

What is the primary consequence of chronic pancreatitis on the pancreatic ductal system?

<p>Alternating stenosis and dilation of the ducts (C)</p> Signup and view all the answers

What is the primary consequence of pancreatic insufficiency on nutrient absorption?

<p>Impaired absorption of dietary fats (D)</p> Signup and view all the answers

What is the primary mechanism of pancreatic duct visualization using ERCP?

<p>Delivering contrast medium through an endoscope to the pancreatic ducts (D)</p> Signup and view all the answers

What is the long-term consequence of chronic pancreatitis on blood sugar regulation?

<p>Diabetes mellitus (B)</p> Signup and view all the answers

What is the primary consequence of pancreatic ductal obstruction in chronic pancreatitis?

<p>Formation of pancreatic pseudocysts (D)</p> Signup and view all the answers

What is the primary goal of treatment for chronic pancreatitis?

<p>Controlling pain and reducing risk factors (B)</p> Signup and view all the answers

What is the primary difference between chronic pancreatitis and acute pancreatitis in terms of pancreatic structure?

<p>Fibrosis, atrophy, and calcification vs. normal pancreatic structure (B)</p> Signup and view all the answers

What is the purpose of producing zymogens in the pancreas?

<p>To protect the pancreas from autodigestion (C)</p> Signup and view all the answers

What is the role of acinar cells in the pancreas?

<p>To manufacture digestive enzymes and proenzymes (C)</p> Signup and view all the answers

What is the location of the pancreas in the body?

<p>In the upper abdomen, behind the stomach (C)</p> Signup and view all the answers

What is the function of the pancreatic digestive enzymes secreted into the duodenum?

<p>To break down macromolecules like carbohydrates, lipids, and proteins (A)</p> Signup and view all the answers

What is the process called when the pancreas is destroyed by its own digestive enzymes?

<p>Autodigestion (C)</p> Signup and view all the answers

Which of the following prevents enzymes from doing damage if they become prematurely active in the pancreas?

<p>Protease inhibitors (D)</p> Signup and view all the answers

What is the primary cause of chronic pancreatitis in children?

<p>Cystic fibrosis (B)</p> Signup and view all the answers

What is the consequence of membrane trafficking becoming chaotic in the pancreas?

<p>Zymogen granules merging with lysosomes (B)</p> Signup and view all the answers

What is the result of the pancreatic juices becoming thick and viscous in the pancreatic duct?

<p>Formation of a plug that can block the duct (D)</p> Signup and view all the answers

What is the term for the process of the pancreas being destroyed by its own digestive enzymes?

<p>Autodigestion (D)</p> Signup and view all the answers

What is the main consequence of repeated bouts of acute pancreatitis?

<p>Development of chronic pancreatitis (A)</p> Signup and view all the answers

What is the primary role of enteropeptidase in the activation of trypsinogen?

<p>To cleave trypsinogen into trypsin (D)</p> Signup and view all the answers

What is the significance of elevated lipase and amylase levels in acute pancreatitis?

<p>They are diagnostic for acute pancreatitis (D)</p> Signup and view all the answers

What is the consequence of high consumption and subsequent oxidative metabolism of alcohol in the pancreas?

<p>Formation of reactive oxygen species (A)</p> Signup and view all the answers

What is the primary mechanism by which alcohol abuse contributes to acute pancreatitis?

<p>By stimulating acinar cells to release inflammatory cytokines (D)</p> Signup and view all the answers

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