Podcast
Questions and Answers
Which theory proposes that each blood cell lineage is derived from its own unique stem cell?
Which theory proposes that each blood cell lineage is derived from its own unique stem cell?
- Polyphyletic theory (correct)
- Monophyletic theory
- Megaloblastic theory
- Medullary theory
What is the predominant cell type during the Mesoblastic/Megaloblastic phase of hematopoiesis?
What is the predominant cell type during the Mesoblastic/Megaloblastic phase of hematopoiesis?
- Megakaryocyte
- Myeloblast
- Primitive Erythroblast (PE) (correct)
- Lymphoblast
Which phase of hematopoiesis is characterized by the liver and spleen as the chief sites of blood cell formation?
Which phase of hematopoiesis is characterized by the liver and spleen as the chief sites of blood cell formation?
- Medullary/Myeloid phase
- Hypocellular/Hypoplastic phase
- Mesoblastic/Megaloblastic phase
- Hepatic phase (correct)
What is the primary site of hematopoiesis during the Medullary/Myeloid phase?
What is the primary site of hematopoiesis during the Medullary/Myeloid phase?
Which phase of hematopoiesis begins in the 5th month of gestation and continues throughout life?
Which phase of hematopoiesis begins in the 5th month of gestation and continues throughout life?
What is the typical site for bone marrow aspiration in adults?
What is the typical site for bone marrow aspiration in adults?
Which theory suggests that all blood cells originate from a single progenitor stem cell?
Which theory suggests that all blood cells originate from a single progenitor stem cell?
During which phase of hematopoiesis is the yolk sac the chief site of blood cell formation?
During which phase of hematopoiesis is the yolk sac the chief site of blood cell formation?
What is the predominant cell type during the 9th week of fetal life in the mesoblastic/megaloblastic phase?
What is the predominant cell type during the 9th week of fetal life in the mesoblastic/megaloblastic phase?
Which phase of hematopoiesis involves the liver as the chief site, with contributions from the spleen and lymph nodes?
Which phase of hematopoiesis involves the liver as the chief site, with contributions from the spleen and lymph nodes?
For bone marrow aspiration in children, which site is typically used?
For bone marrow aspiration in children, which site is typically used?
Study Notes
Theories of Hematopoiesis
- The theory of separate stem cells proposes that each blood cell lineage is derived from its own unique stem cell.
- The unitary theory suggests that all blood cells originate from a single progenitor stem cell.
Phases of Hematopoiesis
Mesoblastic/Megaloblastic Phase
- This phase is characterized by the presence of megaloblasts as the predominant cell type.
- The yolk sac is the chief site of blood cell formation during this phase.
Hepatolymphatic Phase
- This phase is characterized by the liver and spleen as the chief sites of blood cell formation, with contributions from the lymph nodes.
- It occurs from the 9th week of fetal life and is characterized by the presence of normoblasts as the predominant cell type.
Medullary/Myeloid Phase
- This phase begins in the 5th month of gestation and continues throughout life.
- The primary site of hematopoiesis during this phase is the bone marrow.
Bone Marrow Aspiration
- In adults, the typical site for bone marrow aspiration is the posterior superior iliac spine.
- In children, the anterior superior iliac spine is typically used for bone marrow aspiration.
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Description
Explore the polyphyletic and monophyletic theories of blood cell formation, along with the Mesoblastic and Megaloblastic phases of hematopoiesis. Delve into the origin of hematopoietic progenitor cells and their development.
