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Questions and Answers
What is the process of proliferation, differentiation, and mature blood cell release called?
What is the process of proliferation, differentiation, and mature blood cell release called?
- Erythropoiesis
- Thrombopoiesis
- Hemopoiesis (correct)
- Leucopoiesis
During which stage of development is the liver a site of hemopoiesis?
During which stage of development is the liver a site of hemopoiesis?
- Infant
- 2-7 months (correct)
- 5-9 months
- Fetus 0-2 months
In which type of anemia is there a deficiency in iron metabolism?
In which type of anemia is there a deficiency in iron metabolism?
- Aplastic anemia
- Hypochromic anemia (correct)
- Megaloblastic anemia
- Sickle cell anemia
Which type of cells in the bone marrow include stem, progenitor, precursor, and mature cells?
Which type of cells in the bone marrow include stem, progenitor, precursor, and mature cells?
What is the ability of stem cells to give rise to all cell lines and to self-renew called?
What is the ability of stem cells to give rise to all cell lines and to self-renew called?
During which stage of development is the bone marrow present in all bones in the body?
During which stage of development is the bone marrow present in all bones in the body?
What is the process of hemopoiesis occurring outside the bone marrow called?
What is the process of hemopoiesis occurring outside the bone marrow called?
Which cells are considered as the site of active hemopoiesis?
Which cells are considered as the site of active hemopoiesis?
What triggers the secretion of Erythropoietin (Epo)?
What triggers the secretion of Erythropoietin (Epo)?
Which of the following accurately describes Reticulocytes?
Which of the following accurately describes Reticulocytes?
Which hormone enhances erythropoiesis?
Which hormone enhances erythropoiesis?
What is the main stimulus for erythropoiesis?
What is the main stimulus for erythropoiesis?
Which cells are required for the complete formation of mature RBC?
Which cells are required for the complete formation of mature RBC?
What is the process requiring stem, progenitor, and precursor cells for complete formation of mature RBC called?
What is the process requiring stem, progenitor, and precursor cells for complete formation of mature RBC called?
Which of the following is NOT a nutritional factor that affects erythropoiesis?
Which of the following is NOT a nutritional factor that affects erythropoiesis?
What is the normal range for retic count (Reticulocyte count)?
What is the normal range for retic count (Reticulocyte count)?
Which procedure involves taking a core of bone marrow tissue for examination?
Which procedure involves taking a core of bone marrow tissue for examination?
What does Normocytic in terms of RBC disorders refer to?
What does Normocytic in terms of RBC disorders refer to?
Which of the following is a common cause of iron deficiency anemia in developing and underdeveloped countries?
Which of the following is a common cause of iron deficiency anemia in developing and underdeveloped countries?
Which of the following is a clinical feature of severe iron deficiency anemia?
Which of the following is a clinical feature of severe iron deficiency anemia?
What is the most common type of anemia, especially in developing countries?
What is the most common type of anemia, especially in developing countries?
What is the triad of dysphagia, glossitis, and iron deficiency anemia known as?
What is the triad of dysphagia, glossitis, and iron deficiency anemia known as?
Which stage of iron deficiency anemia initially involves depletion of iron stores but no anemia?
Which stage of iron deficiency anemia initially involves depletion of iron stores but no anemia?
What does hepcidin inhibit to regulate iron balance in the body?
What does hepcidin inhibit to regulate iron balance in the body?
Which condition involves an increase in Hb concentration above the upper limit of normal for age and sex?
Which condition involves an increase in Hb concentration above the upper limit of normal for age and sex?
What is the main method of iron loss from the body?
What is the main method of iron loss from the body?
What is a characteristic feature seen in the blood film morphology of iron deficiency anemia?
What is a characteristic feature seen in the blood film morphology of iron deficiency anemia?
Which laboratory finding is typically associated with iron deficiency anemia?
Which laboratory finding is typically associated with iron deficiency anemia?
What is a potential consequence of severe, long-standing iron deficiency anemia?
What is a potential consequence of severe, long-standing iron deficiency anemia?
What stage of iron deficiency anemia involves low serum ferritin levels and no anemia?
What stage of iron deficiency anemia involves low serum ferritin levels and no anemia?
Which of the following is a characteristic feature of iron deficiency anemia?
Which of the following is a characteristic feature of iron deficiency anemia?
What is the typical presentation of a patient with severe long-standing iron deficiency anemia (IDA)?
What is the typical presentation of a patient with severe long-standing iron deficiency anemia (IDA)?
What is the main cause of iron deficiency in developing and underdeveloped countries?
What is the main cause of iron deficiency in developing and underdeveloped countries?
Which of the following is a common cause of chronic blood loss leading to iron deficiency anemia?
Which of the following is a common cause of chronic blood loss leading to iron deficiency anemia?
What is a typical mucosal change associated with severe iron deficiency anemia?
What is a typical mucosal change associated with severe iron deficiency anemia?
In which type of anemia is there a decrease in hemoglobin concentration below the normal range for age and sex?
In which type of anemia is there a decrease in hemoglobin concentration below the normal range for age and sex?
What is the primary cause of increased hepcidin production?
What is the primary cause of increased hepcidin production?
Which laboratory finding is typically observed in iron deficiency anemia?
Which laboratory finding is typically observed in iron deficiency anemia?
What is the characteristic appearance of red blood cells in iron deficiency anemia?
What is the characteristic appearance of red blood cells in iron deficiency anemia?
Which of the following symptoms is associated with severe long-standing iron deficiency anemia?
Which of the following symptoms is associated with severe long-standing iron deficiency anemia?
Which process involves the proliferation, differentiation, and release of mature blood cells?
Which process involves the proliferation, differentiation, and release of mature blood cells?
During which stage of development is the bone marrow present in all bones in the body?
During which stage of development is the bone marrow present in all bones in the body?
What type of cells can give rise to all cell lines, self-renew, and require certain growth factors and a suitable microenvironment to work?
What type of cells can give rise to all cell lines, self-renew, and require certain growth factors and a suitable microenvironment to work?
Where is the site of active hemopoiesis in adults?
Where is the site of active hemopoiesis in adults?
Which stage of iron deficiency anemia initially involves depletion of iron stores but no anemia?
Which stage of iron deficiency anemia initially involves depletion of iron stores but no anemia?
What is the process of taking a core of bone marrow tissue for examination called?
What is the process of taking a core of bone marrow tissue for examination called?
What is the process of formation of red blood cells called?
What is the process of formation of red blood cells called?
Which hormone stimulates red cell progenitors and precursor cells for RBC formation from the bone marrow?
Which hormone stimulates red cell progenitors and precursor cells for RBC formation from the bone marrow?
Which cell is the site of active hematopoiesis?
Which cell is the site of active hematopoiesis?
Which condition involves the process of hemopoiesis occurring outside the bone marrow, mainly in the liver and spleen?
Which condition involves the process of hemopoiesis occurring outside the bone marrow, mainly in the liver and spleen?
What is the term for an increase in young, immature non-nucleated red blood cells?
What is the term for an increase in young, immature non-nucleated red blood cells?
What is the hormone primarily produced by the kidney and stimulates red cell progenitors and precursor cells for RBC formation?
What is the hormone primarily produced by the kidney and stimulates red cell progenitors and precursor cells for RBC formation?
Which of the following is a characteristic feature of iron deficiency anemia?
Which of the following is a characteristic feature of iron deficiency anemia?
What is the characteristic appearance of mature RBCs?
What is the characteristic appearance of mature RBCs?
What is the process that requires stem, progenitor, and precursor cells for complete formation of mature RBC?
What is the process that requires stem, progenitor, and precursor cells for complete formation of mature RBC?
What is the main stimulus for erythropoiesis?
What is the main stimulus for erythropoiesis?
What term refers to variation in RBC size as microcytic or macrocytic?
What term refers to variation in RBC size as microcytic or macrocytic?
What is a characteristic feature seen in the blood film morphology of iron deficiency anemia?
What is a characteristic feature seen in the blood film morphology of iron deficiency anemia?
Which of the following is a typical mucosal change associated with severe iron deficiency anemia?
Which of the following is a typical mucosal change associated with severe iron deficiency anemia?
What is the main stimulus for erythropoiesis in iron deficiency anemia?
What is the main stimulus for erythropoiesis in iron deficiency anemia?
Which of the following laboratory findings is typically observed in iron deficiency anemia?
Which of the following laboratory findings is typically observed in iron deficiency anemia?
What is the primary cause of increased hepcidin production in iron deficiency anemia?
What is the primary cause of increased hepcidin production in iron deficiency anemia?
Which stage of iron deficiency anemia initially involves depletion of iron stores but no anemia?
Which stage of iron deficiency anemia initially involves depletion of iron stores but no anemia?
What triggers the secretion of Erythropoietin (Epo) in iron deficiency anemia?
What triggers the secretion of Erythropoietin (Epo) in iron deficiency anemia?
Which of the following symptoms is associated with severe long-standing iron deficiency anemia?
Which of the following symptoms is associated with severe long-standing iron deficiency anemia?
What is a potential consequence of severe, long-standing iron deficiency anemia?
What is a potential consequence of severe, long-standing iron deficiency anemia?
In which type of anemia is there a deficiency in iron metabolism?
In which type of anemia is there a deficiency in iron metabolism?
What is a characteristic feature seen in the blood film morphology of iron deficiency anemia?
What is a characteristic feature seen in the blood film morphology of iron deficiency anemia?
What does hepcidin inhibit to regulate iron balance in the body?
What does hepcidin inhibit to regulate iron balance in the body?
What is the main method of iron loss from the body in normal physiological conditions?
What is the main method of iron loss from the body in normal physiological conditions?
What is the main pathophysiological mechanism involved in the development of anaemia of chronic disease?
What is the main pathophysiological mechanism involved in the development of anaemia of chronic disease?
Which type of anaemia is characterized by normochromic normocytic or mildly hypochromic red cells?
Which type of anaemia is characterized by normochromic normocytic or mildly hypochromic red cells?
Which laboratory finding is typically associated with anaemia of chronic disease?
Which laboratory finding is typically associated with anaemia of chronic disease?
What is the primary cause of anaemia due to impaired DNA synthesis, resulting mainly from B12 and folate deficiency?
What is the primary cause of anaemia due to impaired DNA synthesis, resulting mainly from B12 and folate deficiency?
Which hormone primarily stimulates red cell progenitors and precursor cells for red blood cell formation from the bone marrow?
Which hormone primarily stimulates red cell progenitors and precursor cells for red blood cell formation from the bone marrow?
What is the characteristic appearance seen in the blood film morphology of megaloblastic anaemia?
What is the characteristic appearance seen in the blood film morphology of megaloblastic anaemia?
What is the likely diagnosis based on the given clinical and laboratory findings?
What is the likely diagnosis based on the given clinical and laboratory findings?
Which of the following is a characteristic feature of the bone marrow findings in this case?
Which of the following is a characteristic feature of the bone marrow findings in this case?
What is the likely cause of the patient's low serum B12 and low serum FA?
What is the likely cause of the patient's low serum B12 and low serum FA?
What is the primary treatment approach for the suspected diagnosis in this case?
What is the primary treatment approach for the suspected diagnosis in this case?
What is the likely impact of therapeutic trials with vitamins B12 and folic acid in this case?
What is the likely impact of therapeutic trials with vitamins B12 and folic acid in this case?
What is the potential consequence of long-standing pernicious anemia on the nervous system?
What is the potential consequence of long-standing pernicious anemia on the nervous system?
Which vitamin is involved in the conversion of Homocysteine to Methionine and the conversion of Methylmalonyl-Co A into succinyl-Co A?
Which vitamin is involved in the conversion of Homocysteine to Methionine and the conversion of Methylmalonyl-Co A into succinyl-Co A?
What is the main form of B12 in the human body?
What is the main form of B12 in the human body?
What is the primary cause of Pernicious anemia?
What is the primary cause of Pernicious anemia?
Which vitamin is involved in co-enzyme in purine and pyrimidine synthesis?
Which vitamin is involved in co-enzyme in purine and pyrimidine synthesis?
What is the primary site for the absorption of Vitamin B12?
What is the primary site for the absorption of Vitamin B12?
What is the typical blood film morphology characteristic of Megaloblastic Anemia?
What is the typical blood film morphology characteristic of Megaloblastic Anemia?
What is the main method of iron loss from the body?
What is the main method of iron loss from the body?
What is the typical mucosal change associated with severe iron deficiency anemia?
What is the typical mucosal change associated with severe iron deficiency anemia?
Which laboratory finding is typically observed in iron deficiency anemia?
Which laboratory finding is typically observed in iron deficiency anemia?
What triggers the secretion of Erythropoietin (Epo)?
What triggers the secretion of Erythropoietin (Epo)?
What does Normocytic in terms of RBC disorders refer to?
What does Normocytic in terms of RBC disorders refer to?
What is a potential consequence of severe, long-standing iron deficiency anemia?
What is a potential consequence of severe, long-standing iron deficiency anemia?
What is the main form of vitamin B12 in the human body?
What is the main form of vitamin B12 in the human body?
Where does absorption of vitamin B12 primarily take place?
Where does absorption of vitamin B12 primarily take place?
Which of the following is a common cause of vitamin B12 deficiency?
Which of the following is a common cause of vitamin B12 deficiency?
What is the primary function of folate in the body?
What is the primary function of folate in the body?
What is the biochemical basis of Megaloblastic Anemia?
What is the biochemical basis of Megaloblastic Anemia?
What is a characteristic feature of hematological findings in Megaloblastic Anemia?
What is a characteristic feature of hematological findings in Megaloblastic Anemia?
What is the main cause of Pernicious Anemia?
What is the main cause of Pernicious Anemia?
Which laboratory finding is typically observed in Pernicious Anemia?
Which laboratory finding is typically observed in Pernicious Anemia?
What is the response to treatment for Megaloblastic Anemia?
What is the response to treatment for Megaloblastic Anemia?
What are the typical bone marrow findings in Megaloblastic Anemia?
What are the typical bone marrow findings in Megaloblastic Anemia?
What is the primary cause of increased hepcidin production in iron deficiency anemia?
What is the primary cause of increased hepcidin production in iron deficiency anemia?
