Hematology: Blood Composition and Clotting
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Questions and Answers

What is the primary phagocytosis function of neutrophils in tissues?

  • Defend against viral infection
  • Produce antibodies
  • Defend against bacterial infection (correct)
  • Produce histamine

    • Why can neutrophils not return to the blood once they leave to enter tissues?

  • They get destroyed in tissues
  • They lose their ability to circulate
  • They are too large to re-enter blood vessels
  • They undergo irreversible changes upon tissue entry (correct)

    • What percentage of the vascular pool do the marginating pool of neutrophils represent?

  • ~50-55% (correct)
  • ~90%
  • ~25%
  • ~75%

    • What distinguishes leukocytes from RBCs?

    <p>Presence of nuclei</p> Signup and view all the answers

    What is the main reason for the increase in circulating neutrophils in response to acute stress?

    <p>Increased neutrophil production</p> Signup and view all the answers

    Which type of leukocytes are segmented cells with granules?

    <p>Neutrophils</p> Signup and view all the answers

    Why are the neutrophil granules referred to as neutrophilic?

    <p>They are acidic components</p> Signup and view all the answers

    What is the significance of the presence of drumstick (Barr body) in some females' neutrophils?

    <p>Has no physiological significance</p> Signup and view all the answers

    What distinguishes band neutrophils from segmented neutrophils?

    <p>Nucleus shape</p> Signup and view all the answers

    What is the typical percentage range of segmented neutrophils in total WBC count?

    <p>~45% to 70%</p> Signup and view all the answers

    Where do leukocytes mainly function?

    <p>In tissues</p> Signup and view all the answers

    Which type of leukocyte represents an earlier stage of segmented neutrophils?

    <p>Band neutrophils</p> Signup and view all the answers

    What is the approximate percentage of the liquid part in the blood volume?

    <p>60-70%</p> Signup and view all the answers

    Why is clotting prevented when blood is mixed with anticoagulant?

    <p>To prevent the blood from forming a solid clot</p> Signup and view all the answers

    What is the liquid remaining after blood clots called?

    <p>Serum</p> Signup and view all the answers

    Which anticoagulant is preferred for blood samples?

    <p>EDTA</p> Signup and view all the answers

    What are the three populations into which blood cells can be divided?

    <p>Erythrocytes, Leukocytes, Thrombocytes</p> Signup and view all the answers

    What percentage of plasma is water?

    <p>90%</p> Signup and view all the answers

    What is the primary function of erythrocytes (red blood cells)?

    <p>Carry oxygen from the lungs to the tissues</p> Signup and view all the answers

    What is the approximate normal red blood cell (RBC) count in a healthy individual?

    <p>4.5 to 6 million cells per microliter</p> Signup and view all the answers

    How are microcytic red blood cells characterized?

    <p>They have a mean corpuscular volume of less than 80 fL</p> Signup and view all the answers

    What is the best estimate of red blood cell (RBC) production?

    <p>Blood reticulocyte count</p> Signup and view all the answers

    What gives red blood cells their flexibility to squeeze through capillaries?

    <p>Their biconcave shape</p> Signup and view all the answers

    What can be observed in young red blood cells that helps in identifying them?

    <p>Visible particles called reticulin</p> Signup and view all the answers

    What is the normal range of eosinophils in total white blood cell count?

    <p>2 to 6%</p> Signup and view all the answers

    Which of the following is NOT a function of eosinophils?

    <p>Production of red blood cells</p> Signup and view all the answers

    Which protein represents approximately 50% of the content in eosinophil granules and has a toxic effect causing cell membrane permeabilization?

    <p>Major basic protein (MBP)</p> Signup and view all the answers

    Where is Charcot-Leyden protein mostly detected in patients with hypereosinophilia?

    <p>Sputum</p> Signup and view all the answers

    What is the average survival time of eosinophils in circulation before they enter tissues?

    <p>~5 to 6 hours</p> Signup and view all the answers

    Which type of infections can lead to an increase in the number of eosinophils in the body?

    <p>Parasitic infections</p> Signup and view all the answers

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