Hematologic System: Chapter 15

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Questions and Answers

Which function of blood is essential for thermoregulation?

  • Transportation of carbon dioxide
  • Regulation of body temperature (correct)
  • Transportation of hormones and enzymes
  • Regulation of fluid volume

What is the primary role of erythrocyte production?

  • Production of antibodies to fight infection
  • Transporting oxygen and carbon dioxide (correct)
  • Filtering leukocytes
  • Promoting blood clotting to prevent excessive bleeding

How do alpha and beta globulins contribute to bodily functions?

  • Facilitating blood clot formation
  • Maintaining osmotic pressure
  • Acting as carriers for drugs and lipids (correct)
  • Functioning as antibodies

Which process is directly facilitated by erythropoietin?

<p>Production of erythrocytes in response to low oxygen levels (A)</p> Signup and view all the answers

What process do lymph nodes perform to prevent infection?

<p>Filtering leukocytes and cell debris (B)</p> Signup and view all the answers

Which change in the hematologic system is most associated with aging?

<p>Reduced bone marrow production of blood cells (C)</p> Signup and view all the answers

What role do platelets play in the hematologic system?

<p>Promoting blood clotting (B)</p> Signup and view all the answers

Which component of blood directly affects osmotic pressure?

<p>Albumin (C)</p> Signup and view all the answers

Based on the provided information, what is the life span of leukocytes?

<p>About 13 to 20 days (D)</p> Signup and view all the answers

What components are found in blood plasma?

<p>Hormones, glucose, and waste products (A)</p> Signup and view all the answers

When the nurse assesses for the function of blood, which assessment findings correlate with this function?

<p>Arterial blood gases (ABGs) with a pH of 7.38 (B)</p> Signup and view all the answers

When the nurse reviews the client's laboratory results, which laboratory value is a component of the formed elements?

<p>Platelets (C)</p> Signup and view all the answers

The nurse is caring for a client with pernicious anemia and knows what about the client's ethnicity?

<p>Scandinavian (D)</p> Signup and view all the answers

Platelets, also called __________ fragments, are fragments of megakaryocytes that are produced by the bone marrow.

<p>Thrombocytes (B)</p> Signup and view all the answers

What medication should the nurse inform the patient about that can cause blood disorders?

<p>Anticoagulants (A)</p> Signup and view all the answers

A client has blood drawn for complete blood count (CBC). Which nursing action is the most important?

<p>Monitor the site for bleeding (B)</p> Signup and view all the answers

The nurse is planning discharge education for a client who receives a prescription for iron supplements due to anemia. Which statement is most important for the nurse to include in the teaching?

<p>&quot;Eat foods high in fiber to prevent constipation.&quot; (A)</p> Signup and view all the answers

When the body loses a considerable amount of blood loss through hemorrhage, which condition can occur?

<p>Anemia (B)</p> Signup and view all the answers

The nurse is assessing the client who has a family history of a genetic disorder. Which referral is most important?

<p>Genetic counseling (C)</p> Signup and view all the answers

An older adult client has a prescription for a vaccine during the annual check-up. What assessment finding is essential for the nurse to monitor?

<p>Antibody response (D)</p> Signup and view all the answers

In maintaining homeostasis by balancing the production of clotting and dissolving factors, platelets are involved in a complex ___________ process.

<p>Hemostasis (A)</p> Signup and view all the answers

Which clinical manifestation can be the result of a hematologic system disorder?

<p>Bone marrow failure (B)</p> Signup and view all the answers

The client is of Middle Eastern origin, which blood disorder is the client prone to?

<p>Thalassemia (C)</p> Signup and view all the answers

The nurse provided an older client with education about diet and blood. What statement indicates the need for further teaching?

<p>&quot;I will make sure to stop taking my blood thinner since I am older.&quot; (D)</p> Signup and view all the answers

The nurse is caring for a client with blood loss. Which body system collaborates with the hematologic system to maintain adequate blood volume?

<p>Renal system (C)</p> Signup and view all the answers

The nurse reviews a client's medication history. Which of the medications has the most potential to alter the client's hematologic system?

<p>Anticoagulants (C)</p> Signup and view all the answers

A client has blood drawn for a complete blood count and asks when the results will be in. Which response by the nurse is most appropriate?

<p>&quot;CBC results usually result in a few hours.&quot; (C)</p> Signup and view all the answers

When the nurse educated a group of patients on preventing hematologic disorders, which patients are most prone to bleeding?

<p>Menstruating woman (C)</p> Signup and view all the answers

An adult reports consistently feeling fatigue with no other symptoms, which diagnostic test is most important for the nurse to educate to the patient about?

<p>Complete blood count (B)</p> Signup and view all the answers

The nurse is caring for a client who has a history of leukemia. Which information is most important?

<p>Ethnicity (C)</p> Signup and view all the answers

A client with a history of anemia provides statements to the nurse. Which statement indicates the need for the nurse to provide more teaching?

<p>&quot;I do not need to eat B12.&quot; (B)</p> Signup and view all the answers

A client asks why is important for the kidneys to work when making blood cells. Which answer is most appropriate?

<p>&quot;The kidney makes erythropoietin.&quot; (D)</p> Signup and view all the answers

An older client has had a significant amount of blood loss, which occurrence of the aging process is most important for the nurse to monitor?

<p>Hypovolemia and shock (A)</p> Signup and view all the answers

Where stem cells are produced?

<p>Bone marrow (B)</p> Signup and view all the answers

What is the normal adult laboratory range for total leukocytes (WBCs)?

<p>4,500 to 11,000/mm3 (A)</p> Signup and view all the answers

What factors affect the hematologic system?

<p>Radiation exposure, medications and heredity (D)</p> Signup and view all the answers

When teaching a pre-op client about post-operative cares, why should the nurse include information about possible hemorrhage?

<p>To prevent anemia (D)</p> Signup and view all the answers

When caring for a client with hemophilia, what teaching is most important to prevent bleeding?

<p>Avoid contact sports (C)</p> Signup and view all the answers

When blood is prone to coagulate with an advancing age because platelets tend to aggregate _______with advancing age?

<p>More (D)</p> Signup and view all the answers

Flashcards

Hematologic System

The hematologic system involves the production, transportation and regulation of blood cells.

Complete Blood Count (CBC)

A complete blood count provides information about the types and numbers of blood cells, as well as other parameters.

Hemostasis

Hemostasis is the process of stopping bleeding, involving platelets and clotting factors.

Bone Marrow Aspiration

Bone marrow aspiration is a procedure to collect and examine bone marrow.

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Functions of Blood

Blood transports water, oxygen, nutrients, hormones, enzymes and medications. It also regulates fluid volume, electrolyte distribution, pH balance and body temperature.

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Components of Blood

Blood is composed of formed elements (cells) and plasma.

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Formed elements in blood

The formed elements are erythrocytes, neutrophils, lymphocytes, monocytes, basophils, and platlets.

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Red Blood Cell (RBC) Function

RBCs contain hemoglobin, which carries oxygen and carbon dioxide.

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Blood types

Each individual has a hereditary blood type based on antigens (A, B, AB, or O).

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White Blood Cells (WBCs)

WBCs provide the first line of defense against microbial agents.

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Platelets Function

Platelets promote clotting when a blood vessel has been damaged.

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Function of Lymph vessels

Lymph vessels collect fluids from tissues and return them to bloodstream.

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Lymph Node function

Lymph node filters out leukocytes and cell debris from inflammations

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Aging impacts on hematologic system

With aging, plasma volume decreases/ reduced bone marrow inhibits production of blood cells/New cells are produced slowly /Antibody response to vaccines decreases

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Preventing Hemorrhage

Significant blood lost through hemorrhage can result in hypovolemia and anemia. Therefore the amount of blood lost, must be vigilantly assessed.

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Preventing Blood disorders

Caution the public about the dangers of radiation / Inform patients about harmful medications

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Plasma proteins

Plasma proteins, such as albumin, globulins, and fibrinogen, are essential for maintaining osmotic pressure, transporting substances, and forming blood clots.

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Erythropoiesis

Blood cells develop from stem cells in the bone marrow through erythropoiesis, with the kidney producing erythropoietin to stimulate RBC production.

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Study Notes

  • The hematologic system is the focus of chapter 15.
  • Nurses can play a role in preventing blood disorders.
  • It's important to understand blood disorders and apply the nursing process for patients with these disorders.
  • Bone marrow aspiration involves specific procedures and care.
  • Nurses should be able to identify appropriate nursing interventions for patients with hematologic system problems.

Functions of Blood

  • Transports water, oxygen, nutrients, enzymes, hormones, and medications to cells
  • Carries carbon dioxide and other waste products away from the cells.
  • Regulates fluid volume and electrolyte distribution.
  • Maintains pH and acid-base balance through buffering
  • Helps to regulate body temperature.
  • Provides clotting factors for hemostasis.

Components of Blood

  • Formed elements and plasma comprise blood.
  • Erythrocytes, neutrophils, lymphocytes, monocytes, basophils, and platelets make up the formed elements.
  • Proteins, water, salts, and dissolved gasses, such as CO2, bicarbonate (HCO3-), hormones, glucose, and wastes make up plasma.
  • Albumin, globulins, and fibrinogen make up plasma proteins.

Functions of Plasma Proteins

  • Albumin maintains osmotic pressure at the capillary membrane.
  • Alpha and beta globulins transport drugs and lipids.
  • Gamma globulins act as antibodies.
  • Fibrinogen forms blood clots.

Production of Blood Cells

  • Blood develops from stem cells in bone marrow through erythropoiesis.
  • The kidney makes erythropoietin, which prompts erythrocyte production.
  • Erythropoiesis requires iron, vitamins B12, C, and E, folic acid, and amino acids.

Functions of Red Blood Cells

  • Hemoglobin is contained in red blood cells, which carry oxygen to cells and carbon dioxide away.
  • Blood type is determined by antigens on RBCs (A, B, AB, or O).
  • Decreased RBCs/hemoglobin reduces oxygen to the body's cells.
  • RBCs live for approximately 120 days.
  • The spleen and liver remove old and damaged red cells.

Function of the White Blood Cells (WBCs)

  • The first line of defense against microbial agents is white blood cells.
  • Adults typically have between 4500 to 11,000 leukocytes (WBCs) /mm3, with a life span of 13 to 20 days.
  • Leukocytes migrate into tissues from bone marrow cells, traveling via the bloodstream.
  • Leukocytes are classified as granulocytes or agranulocytes, determined by the cell nucleus.

Platelets and Their Function

  • Megakaryocyte fragments are produced by the bone marrow and also called thrombocytes
  • Platelets provide first-line protection to prevent bleeding, promoting clotting when a blood vessel is damaged
  • Platelets maintain hemostasis by balancing clotting and dissolving factors.
  • Fibrin strands attach to aggregated platelets with the plasma protein fibrinogen, to help form a clot.
  • Platelets tend to stick to damaged surfaces and clump together.

Interaction Between Lymphatic and Vascular Systems

  • Lymph vessels gather fluid and protein from the interstitial spaces and return them to the bloodstream.
  • Lymph nodes filter out leukocytes and cell debris from inflammations and infections before the lymph returns to the bloodstream.

Changes of the Hematologic System With Aging

  • Plasma volume decreases after age 60.
  • Reduced bone marrow inhibits blood cell production, decreasing the immune response.
  • New cells are produced more slowly, making anemia harder to correct.
  • The antibody response to vaccines decreases.
  • Older adults are at higher risk for hypovolemia and shock if blood loss occurs.
  • Platelets aggregate more, so blood is more prone to coagulate.
  • Decreased hematocrit
  • Decreased red blood cells

Causes of Hematologic Disorders

  • Anemia
  • Blood loss and hemorrhage
  • Hemolysis
  • Hemophilia
  • Sickle cell disease
  • Thalassemia

Genetic Hematologic Tendencies

  • African Americans have the highest incidence of sickle cell disease.
  • Pernicious anemia is more prevalent among those of Scandinavian descent and among African Americans.
  • People of Middle Eastern origin may have a genetic predisposition to thalassemia.
  • Caucasians have a higher incidence of leukemia.

Prevention of Hematologic Disorders

  • Anemia can result from significant blood loss during hemorrhage.
  • Excessive blood loss can occur during menstruation.
  • Hemorrhage can be prevented after surgery or childbirth.

Preventing Blood Disorders

  • Cautions against ionizing radiation and harmful chemicals should be issued to the public.
  • Adults with a genetic disorder should seek genetic counseling.
  • Patients should be informed about medications that can cause blood disorders. - Periodic CBC checks are suggested.
  • Excessive bleeding
  • Excessive clotting
  • Fatigue
  • Anorexia
  • Pain
  • Infection
  • Bone marrow failure

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