Week 2 - Hematologic Neoplasms Quiz

Symptoms present at time of staging

radiation

<p>Circulating tumors primarily involving blood and bone marrow. (C)</p> Signup and view all the answers

<p>False (B)</p> Signup and view all the answers

<p>B-cell plasma cells</p> Signup and view all the answers

<p>granulocytes</p> Signup and view all the answers

<p>Lymphoid lineage (A)</p> Signup and view all the answers

<p>Leukemia = Disseminated circulating tumors Lymphoma = Tends to localize in lymph tissues, often disseminated at diagnosis Plasma cell myeloma = Malignant B-cell plasma cells, localized tumors</p> Signup and view all the answers

<p>cell type</p> Signup and view all the answers

<p>Autologous stem cell transplant (B)</p> Signup and view all the answers

<p>False (B)</p> Signup and view all the answers

<p>Reed-Sternberg cells</p> Signup and view all the answers

<p>lymphatic</p> Signup and view all the answers

<p>30% (A)</p> Signup and view all the answers

<p>False (B)</p> Signup and view all the answers

<p>Epstein-Barr virus</p> Signup and view all the answers

<p>95</p> Signup and view all the answers

<p>85% (A)</p> Signup and view all the answers

<p>They produce excessive identical monoclonal antibodies. (A)</p> Signup and view all the answers

<p>False (B)</p> Signup and view all the answers

<p>30%-95%</p> Signup and view all the answers

<p>confirm</p> Signup and view all the answers

<p>Monoclonal antibody peak = Excessive production of identical antibodies Bence Jones protein = Light chain antibody fragments in blood and urine Hypercalcemia = Increased calcium levels in the blood due to bone destruction Bone lesions = Damage and destruction of bone tissue</p> Signup and view all the answers

<p>Hypercalcemia (B)</p> Signup and view all the answers

<p>False (B)</p> Signup and view all the answers

<p>serum protein electrophoresis</p> Signup and view all the answers

<p>bone</p> Signup and view all the answers

<p>Monoclonal gammopathy of undetermined significance (MGUS) (D)</p> Signup and view all the answers

<p>True (A)</p> Signup and view all the answers

<p>25%</p> Signup and view all the answers

<p>serum calcium</p> Signup and view all the answers

<p>“Honeycomb” appearance (A)</p> Signup and view all the answers

<p>False (B)</p> Signup and view all the answers

<p>Increased blood clotting (B)</p> Signup and view all the answers

<p>hypercalcemia</p> Signup and view all the answers

<p>protein</p> Signup and view all the answers

<p>Hyperproteinemia = Excessive protein levels in the blood, contributing to kidney stress Bence Jones protein = Light chain proteins that can damage kidney tubules Hypercalcemia = Elevated calcium levels contributing to kidney dysfunction Hyperuricemia = Elevated uric acid levels that may compromise renal function</p> Signup and view all the answers

Types of leukemia differ based on malignant transformation processes.

Acute leukemia progresses quickly; chronic leukemia develops slowly.

Malignant disorders of white blood cells lead to decreased bone marrow function.

A type of lymphoma differentiated by clinical and histological features.

Staging procedures assess the extent of lymphoma spread.

A cancer resulting from malignant transformation of B-cell plasma cells, forming tumors in bones.

Hematologic neoplasms are categorized by cell types: myeloid and lymphoid lineages.

Identical antibodies produced by a single clone of plasma cells, characteristic of myeloma.

Light-chain antibody fragments produced by malignant plasma cells; found in blood and urine.

Increased calcium in the bloodstream, often due to bone destruction in myeloma.

Abnormal areas in bones caused by plasma cell accumulation, leading to fractures.

A diagnostic test to detect specific proteins in blood, helping confirm myeloma.

Fractures occurring from bone damage due to myeloma, highlighting weakened bones.

A diagnostic procedure to examine plasma cells in the bone marrow for confirming myeloma.

Abnormal increase of plasma cells in bone marrow, essential for diagnosing myeloma.

Hodgkin Disease often shows no symptoms in the early phases.

Swelling of lymph nodes without pain, common in Hodgkin Disease.

A classification system that stages Hodgkin Disease based on symptoms and node locations.

Stage A indicates no symptoms; Stage B indicates symptoms present.

Localized means confined to one area, disseminated means spread throughout the body.

A premalignant condition with excess monoclonal antibodies but no symptoms.

Period where individuals show no symptoms despite having MGUS.

Diagnosis may occur during routine examinations with protein in urine or high serum calcium.

Bone pain is usually the first indicator of the disease.

Signs of low bone marrow activity include anemia, recurrent infections, and bleeding tendencies.

50% of patients experience kidney issues due to various factors related to myeloma.

X-rays of affected bones show a 'honeycomb' pattern, indicating damage.

Prognosis can vary with treatment, but often involves maintaining remission.

A treatment option for multiple myeloma includes autologous stem cell transplantation.

A procedure where a patient's own stem cells are used for treatment.

Pharmacologic management to address kidney problems in patients.

Medications used for severe pain, derived from opium.

Malignant cells that are characteristic of Hodgkin Disease.

A virus often found in Reed–Sternberg cells, linked to Hodgkin Disease.

The percentage of patients alive five years after diagnosis or treatment.

The most common form of Hodgkin Disease, accounting for 95% of cases.

A rare type of Hodgkin Disease affecting 5% of cases.