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Questions and Answers
What is defined as heart failure with reduced ejection fraction (HFrEF)?
What is defined as heart failure with reduced ejection fraction (HFrEF)?
Once a patient moves to a higher stage of heart failure, they can regress to an earlier stage.
Once a patient moves to a higher stage of heart failure, they can regress to an earlier stage.
False
What is a significant characteristic of heart failure with preserved ejection fraction (HFpEF)?
What is a significant characteristic of heart failure with preserved ejection fraction (HFpEF)?
LVEF ≥ 50%
Heart failure with improved ejection fraction (HFimpEF) is defined as symptomatic heart failure with a baseline LVEF __________ and an increase to at least 40%.
Heart failure with improved ejection fraction (HFimpEF) is defined as symptomatic heart failure with a baseline LVEF __________ and an increase to at least 40%.
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Match the stages of heart failure with their focus of therapeutic interventions:
Match the stages of heart failure with their focus of therapeutic interventions:
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Which of the following symptoms is NOT commonly associated with heart failure?
Which of the following symptoms is NOT commonly associated with heart failure?
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Edema in heart failure primarily occurs in the upper body.
Edema in heart failure primarily occurs in the upper body.
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What nighttime symptom characterized by breathlessness may occur in individuals with heart failure?
What nighttime symptom characterized by breathlessness may occur in individuals with heart failure?
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Heart failure can lead to kidney damage due to reduced blood flow, ultimately resulting in ________ failure.
Heart failure can lead to kidney damage due to reduced blood flow, ultimately resulting in ________ failure.
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Match the symptoms of heart failure with their descriptions:
Match the symptoms of heart failure with their descriptions:
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Study Notes
Heart Failure Overview
- Heart failure is a chronic and progressive condition where the heart cannot pump sufficient blood to meet the body's needs for oxygen and nutrients.
- The heart can either become weak (unable to pump) or stiff (unable to fill).
Body Compensation Mechanisms
- The body compensates through means such as narrowing blood vessels to maintain blood pressure.
- Blood may be diverted from less essential organs, like the kidneys.
- These compensatory measures delay the recognition of heart failure, leading to possible years of undiagnosed decline.
Affected Heart Sides
- Heart failure can affect the left side, right side, or both, with the left side usually being affected first.
Stages of Heart Failure
- New classification emphasizes the symptomatic nature:
- At-risk for heart failure (Stage A)
- Pre-heart failure (Stage B)
- Symptomatic heart failure (Stage C)
- Advanced heart failure (Stage D)
Left Ventricular Ejection Fraction (LVEF)
- LVEF is crucial in classifying heart failure patients, influencing prognosis and treatment.
- Ejection fraction (EF) measures the percentage of blood pumped from the left ventricle with each contraction.
Heart Failure Classifications Based on LVEF
- HF with reduced ejection fraction (HFrEF): LVEF ≤ 40%
- HF with mildly reduced ejection fraction (HFmrEF): LVEF 41-49%
- HF with preserved ejection fraction (HFpEF): LVEF ≥ 50%
- HF with improved ejection fraction (HFimpEF): LVEF ≤ 40% initially, with a ≥ 10-point increase and LVEF ≥ 40% in subsequent measurements.
ACC/AHA Stages of Heart Failure
- Recognize that risk factors and structural abnormalities are linked to heart failure progression.
- Stages are definitive; once progressed, regression to an earlier stage is not possible.
Progression and Survival
- Advancement through stages correlates with decreased 5-year survival rates.
- Increased plasma natriuretic peptide concentrations are also observed with progression.
Therapeutic Interventions
- Interventions vary by stage:
- Stage A: Modify risk factors.
- Stage B: Treat underlying structural heart disease.
- Stages C & D: Focus on reducing morbidity and mortality.
Important Risk Factors for Heart Failure
- Hypertension: A major contributor to heart failure due to increased pressure on the heart.
- Diabetes Mellitus: Elevates risk due to potential damage to blood vessels and nerves affecting heart function.
- Metabolic Syndrome: A cluster of conditions increasing risk of heart disease and diabetes.
- Atherosclerotic Disease: Build-up of fatty deposits in artery walls, narrowing blood vessels.
- Obesity: Excess body weight strains the heart and can lead to other risk factors.
- Increased Age: Risk rises significantly with advancing age, often due to accumulated health issues.
- Anemia: Low red blood cell count can impair oxygen delivery, stressing the heart.
- Atrial Fibrillation: Irregular heart rhythm that can contribute to heart failure.
- Valvular Heart Disease: Dysfunction of heart valves can disrupt blood flow.
- Congenital Heart Disease: Structural heart abnormalities present from birth may lead to heart failure.
- Severe Lung Disease: Impairs oxygenation and places extra stress on the heart.
- Sleep Apnea: Disrupts breathing during sleep, leading to strain on cardiovascular health.
- Unhealthy behaviors like smoking, poor diet, inactivity, and excessive alcohol can significantly increase risk.
Common Causes in the U.S.
- Hypertension and coronary artery disease (including atherosclerosis) are primary risks leading to heart failure.
- Impaired left ventricular myocardial function is commonly linked to heart failure, but it can arise from various conditions.
Common Comorbid Conditions in Heart Failure Patients
- Hypertension, Ischemic heart disease, Hyperlipidemia, Anemia, Diabetes.
- Other comorbidities include arthritis, chronic kidney disease, chronic obstructive pulmonary disease, and Atrial Fibrillation.
- Cognitive issues like Alzheimer’s disease or dementia, along with depression and asthma, frequently coexist with heart failure.
Symptoms of Heart Failure
-
Breathing Difficulties:
- Dyspnea during physical activity or at rest.
- Paroxysmal nocturnal dyspnea: waking up short of breath during the night.
- Orthopnea: discomfort while lying flat.
- Persistent cough or wheezing, potentially producing pink, blood-tinged sputum.
-
Fluid Buildup (Edema):
- Swelling in feet, ankles, or legs due to fluid retention.
- Increased nocturia: frequent urination at night.
- Ascites: abdominal swelling, often accompanied by nausea or lack of appetite.
-
Low Cardiac Output:
- Fatigue and tiredness from the heart's inability to meet the body's demands.
- Cold extremities and confusion indicating reduced blood flow to limbs and brain.
- Increased heart rate as the body compensates for inadequate blood flow.
Long-term Complications of Heart Failure
- Kidney Damage: Reduced blood flow can lead to kidney failure, potentially requiring dialysis.
- Heart Valve Problems: Enlarged heart or high pressure may impair valve function.
- Heart Rhythm Problems: Arrhythmias can either lead to or worsen heart failure.
- Liver Damage: Fluid accumulation can pressure the liver, leading to scarring and functional impairment.
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Description
This quiz provides an overview of heart failure, a chronic condition affecting the heart's ability to pump blood effectively. Explore the mechanisms the body uses to compensate for heart function decline and understand the implications of this progressive disease. Test your knowledge on the effects, causes, and management of heart failure.