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Questions and Answers
What is the approximate 5-year mortality rate for heart failure?
What is the approximate 5-year mortality rate for heart failure?
- 75%
- 25%
- 50% (correct)
- 90%
What is the most common cause of heart failure in the USA?
What is the most common cause of heart failure in the USA?
- Myocardial infarction
- Cardiomyopathy
- Coronary artery disease (correct)
- Hypertension
In systolic failure, what is typically reduced?
In systolic failure, what is typically reduced?
- Stroke volume
- Ejection fraction (correct)
- Cardiac output
- All of the above
Which type of heart failure is more common in older patients?
Which type of heart failure is more common in older patients?
What is a characteristic of diastolic failure?
What is a characteristic of diastolic failure?
What is the trend in the prevalence of heart failure?
What is the trend in the prevalence of heart failure?
What are the two primary goals of treatment in heart failure?
What are the two primary goals of treatment in heart failure?
What is the name of the plant family that provides medically useful cardiac glycosides?
What is the name of the plant family that provides medically useful cardiac glycosides?
What is the extent of absorption of digoxin after oral administration?
What is the extent of absorption of digoxin after oral administration?
Where are cardiac glycosides distributed in the body?
Where are cardiac glycosides distributed in the body?
How is digoxin primarily eliminated from the body?
How is digoxin primarily eliminated from the body?
What is the relationship between digoxin's renal clearance and creatinine clearance?
What is the relationship between digoxin's renal clearance and creatinine clearance?
What is the primary mechanism by which cardiac glycosides increase cardiac contractility?
What is the primary mechanism by which cardiac glycosides increase cardiac contractility?
What is the result of the inhibition of Na+/K+-ATPase by cardiac glycosides?
What is the result of the inhibition of Na+/K+-ATPase by cardiac glycosides?
What is the role of the sodium-calcium exchanger in the mechanism of cardiac glycosides?
What is the role of the sodium-calcium exchanger in the mechanism of cardiac glycosides?
What is the effect of cardiac glycosides on the electrical properties of the heart?
What is the effect of cardiac glycosides on the electrical properties of the heart?
What is the mechanism by which cardiac glycosides increase the free calcium concentration in the vicinity of the contractile proteins?
What is the mechanism by which cardiac glycosides increase the free calcium concentration in the vicinity of the contractile proteins?
What is the therapeutic effect of cardiac glycosides?
What is the therapeutic effect of cardiac glycosides?
What is the primary effect of cardiac glycosides on the cardiac action potential?
What is the primary effect of cardiac glycosides on the cardiac action potential?
What is the main mechanism by which cardiac glycosides slow AV conduction?
What is the main mechanism by which cardiac glycosides slow AV conduction?
What is the consequence of an excessively rapid ventricular rate?
What is the consequence of an excessively rapid ventricular rate?
What is the effect of larger doses of glycosides on sinus rhythm?
What is the effect of larger doses of glycosides on sinus rhythm?
What is the result of inhibition of the Na+/K+ pump by glycosides?
What is the result of inhibition of the Na+/K+ pump by glycosides?
What is the potential consequence of slowing AV conduction by cardiac glycosides?
What is the potential consequence of slowing AV conduction by cardiac glycosides?
What is the consequence of increased [Ca2+]i in the cardiac muscle?
What is the consequence of increased [Ca2+]i in the cardiac muscle?
What is the primary site of digitalis toxicity outside the heart?
What is the primary site of digitalis toxicity outside the heart?
What is the cause of gastrointestinal toxicity associated with digitalis?
What is the cause of gastrointestinal toxicity associated with digitalis?
What is a rare effect of digitalis in men?
What is a rare effect of digitalis in men?
What is a possible CNS effect of digitalis?
What is a possible CNS effect of digitalis?
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