10 Questions
What is the result of increased [Ca2+]i in the heart?
Coupled beats, followed by ventricular tachycardia, and eventually ventricular fibrillation
What is the most common site of digitalis toxicity outside the heart?
Gastrointestinal tract
What is the cause of anorexia, nausea, vomiting, and diarrhea in digitalis toxicity?
Both direct effects on the gastrointestinal tract and CNS actions
What is the effect of digitalis on the CNS?
Both vagal and chemoreceptor trigger zone stimulation
What is a rare effect reported in men taking digitalis?
Gynecomastia
What is the immediate effect of increased [Ca2+]i on the heart rhythm?
Coupled beats (bigeminy)
What is the effect of digitalis toxicity on the heart?
Abnormal heart rhythms, including ventricular tachycardia and fibrillation
What is the cause of visual disturbances in digitalis toxicity?
CNS actions
What is a common symptom of digitalis toxicity in the elderly?
Disorientation and hallucinations
What type of tissues are affected by cardiac glycosides?
All excitable tissues, including smooth muscle and the CNS
Test your knowledge of heart failure, its causes, types, and consequences. Learn about the mortality rate, common causes, and differences in systolic and diastolic failure.
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