Heart Development and Anatomy Quiz

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Questions and Answers

What structures contribute to the outflow tracts of both ventricles during heart development?

  • Atrial portion and Bulbus cordis
  • Secondary Heart Field and Neural Crest Cells (correct)
  • Oropharyngeal membrane and Truncus arteriosus
  • Primary Heart Field and Neural Crest Cells

Which chamber of the heart does the bulbus cordis primarily develop into?

  • Right ventricle (correct)
  • Pulmonary artery
  • Common atrium
  • Left atrium

At what stage does the cardiac tube begin to bend and form the cardiac loop?

  • Day 23 (correct)
  • Day 25
  • Day 20
  • Day 28

What does the primary heart field primarily give rise to?

<p>Initial heart tube (A)</p> Signup and view all the answers

Which structure is formed by the distal part of the bulbus cordis?

<p>Truncus arteriosus (B)</p> Signup and view all the answers

The transformation of the primitive ventricle into its trabeculated state is indicative of which developmental stage?

<p>Bulboventricular loop completion (C)</p> Signup and view all the answers

Cells from the right side of the Secondary Heart Field contribute to which aspect of heart formation?

<p>Outflow tract of the right ventricle (B)</p> Signup and view all the answers

Which of the following best describes the location of the Primary Heart Field?

<p>Anterior lateral plate mesoderm (D)</p> Signup and view all the answers

Which characteristic distinguishes the right ventricle from the left ventricle?

<p>More trabeculated structure (C)</p> Signup and view all the answers

What is the primary function of the AV node within the heart's conduction system?

<p>To slow down the conduction between atria and ventricles (D)</p> Signup and view all the answers

Which statement correctly describes the arrangement of papillary muscles in the tricuspid valve?

<p>Three sets of papillary muscles attached to three leaflets (C)</p> Signup and view all the answers

What role do Purkinje fibers play in the heart's conduction system?

<p>They extend into the walls of the ventricles to propagate signals (B)</p> Signup and view all the answers

Which feature is unique to the left atrium compared to the right atrium?

<p>More muscular atrial wall (D)</p> Signup and view all the answers

How does sympathetic stimulation affect the AV conduction system?

<p>It speeds up conduction through the AV node (D)</p> Signup and view all the answers

Which of the following statements is true regarding the interventricular septum (IVS)?

<p>It has a large muscular inferior part and a small membranous superior part (B)</p> Signup and view all the answers

Which valve auscultation location is associated with the tricuspid valve?

<p>Right fourth intercostal space near the sternum (A)</p> Signup and view all the answers

Which structure is primarily stimulated by the subendocardial branches of the left bundle in the conduction system of the heart?

<p>Posterior papillary muscle (B), Left ventricle wall (C)</p> Signup and view all the answers

What is the role of the AV nodal artery in the cardiac conduction system?

<p>Supplies the AV node (A)</p> Signup and view all the answers

What type of nerve fibers comprise the cardiac plexus?

<p>Sympathetic and parasympathetic fibers (D)</p> Signup and view all the answers

Which of the following components is responsible for the pain sensation associated with heart conditions?

<p>Visceral afferent components (A), Sympathetic nerves (B)</p> Signup and view all the answers

What type of blood supply does the endocardium receive?

<p>Oxygen through diffusion or microvasculature (C)</p> Signup and view all the answers

Where do the right and left coronary arteries originate?

<p>From the aortic sinuses superior to the aortic valve (C)</p> Signup and view all the answers

What is the function of the subendocardial branches of the right bundle?

<p>Stimulating the IVS and right ventricle muscle (B)</p> Signup and view all the answers

In the innervation of the heart, where are the postsynaptic parasympathetic cell bodies located?

<p>Along the coronary arteries and near the SA and AV nodes (C)</p> Signup and view all the answers

What embryonic structure contributes to the development of the atrial septae?

<p>Endocardial cushions (C)</p> Signup and view all the answers

Which cardiac structure is primarily responsible for the maintenance of proper valve function during contraction?

<p>Chordae tendinae (D)</p> Signup and view all the answers

In which phase of development does vasculogenesis primarily occur?

<p>Early embryonic phase (D)</p> Signup and view all the answers

Which coronary artery supplies the sinoatrial node in the heart?

<p>SA-nodal artery (D)</p> Signup and view all the answers

What change occurs to the fetal shunts immediately after birth?

<p>Closure of the foramen ovale (D)</p> Signup and view all the answers

What is the primary role of gap junctions in cardiac tissue?

<p>Facilitate electrical conduction (B)</p> Signup and view all the answers

Which of the following vessels does not directly contribute to the coronary circulation?

<p>Femoral vein (B)</p> Signup and view all the answers

What is the primary function of the endocardial cushions during heart development?

<p>To divide the atrioventricular canal into right and left canals (A)</p> Signup and view all the answers

What embryological process is described by the folding of the lateral body walls to form the basic outline of the heart?

<p>Lateral folding (C)</p> Signup and view all the answers

During which developmental stage does blood flow first enter the primordial atrium?

<p>When the sinus venosus connects to the primordial atrium (B)</p> Signup and view all the answers

Which embryonic structure ultimately contributes to the formation of the smooth part of the atria in the adult heart?

<p>Sinus venosus (D)</p> Signup and view all the answers

What structures does the bulbus cordis develop into during heart development?

<p>Trabeculated part of the right ventricle and outflow tracts (D)</p> Signup and view all the answers

How do endocardial cushions function in the development of AV valves?

<p>By fusing to partially separate atrium from ventricle (C)</p> Signup and view all the answers

What is the primary function of the myocardium layer in the heart?

<p>Contracts to pump blood throughout the circulatory system (B)</p> Signup and view all the answers

Which structure plays a crucial role in the contraction of the atria?

<p>Pectinate muscles (D)</p> Signup and view all the answers

What is contained in the subepicardial layer of the heart?

<p>Adipose tissue and coronary vessels (C)</p> Signup and view all the answers

What unique feature do Purkinje fibers possess compared to other myocardium components?

<p>They are gap junction-rich, allowing rapid signal conduction (B)</p> Signup and view all the answers

Which layer of the heart is known for its thin, external composition and mesothelial origin?

<p>Visceral layer of pericardium (A)</p> Signup and view all the answers

What primarily connects the papillary muscles to the AV valves?

<p>Chordae tendineae (B)</p> Signup and view all the answers

What is the primary tissue composition of the myocardium?

<p>Cardiac muscle (D)</p> Signup and view all the answers

Which structure's primary role is to maintain the integrity of the myocardium within the inner ventricular walls?

<p>Trabeculae carneae (B)</p> Signup and view all the answers

What is the primary function of desmosomes in cardiac muscle tissue?

<p>Prevent cells from separating during contraction (D)</p> Signup and view all the answers

Which layer is NOT a component of the endocardium?

<p>Dense irregular connective tissue (B)</p> Signup and view all the answers

Which statement accurately reflects the composition of cardiac muscle cells?

<p>They are uninucleated with the nucleus centrally located. (A)</p> Signup and view all the answers

What is one key role of the fibrous skeleton in the heart?

<p>Anchor the myocardium and maintain valve shape (A)</p> Signup and view all the answers

Which specific structures are formed from the endocardial cells?

<p>Heart valves and Purkinje fibers (D)</p> Signup and view all the answers

What feature distinguishes cardiac muscle fibers from skeletal muscle fibers?

<p>Intercalated discs are present and facilitate electrical coupling. (D)</p> Signup and view all the answers

Which component of the cardiac muscle cell is primarily responsible for its resistance to fatigue?

<p>Numerous large mitochondria present (B)</p> Signup and view all the answers

What role do gap junctions play in cardiac muscle tissue?

<p>They enable the heart to function as a syncytium by facilitating electrical coupling. (B)</p> Signup and view all the answers

What structure brings oxygenated blood to the embryonic heart?

<p>The umbilical vein (C)</p> Signup and view all the answers

At which intercostal space can the aortic valve be auscultated?

<p>2nd right intercostal space (B)</p> Signup and view all the answers

Which cardiac structure is the papillary muscle primarily attached to?

<p>The chordae tendinae of an atrioventricular valve (C)</p> Signup and view all the answers

Which layer of the pericardium is described as a tough, inelastic connective tissue?

<p>Outer fibrous pericardium (B)</p> Signup and view all the answers

What is the anatomical position of the heart relative to the thoracic cavity?

<p>2/3rd to the left and 1/3rd to the right of the median plane (B)</p> Signup and view all the answers

What is the primary role of the pericardium surrounding the heart?

<p>To anchor the heart and allow frictionless movement (B)</p> Signup and view all the answers

Which structure is located at the apex of the heart during auscultation?

<p>Mitral valve (C)</p> Signup and view all the answers

What subdivision of the mediastinum is located anteriorly?

<p>Anterior mediastinum (A)</p> Signup and view all the answers

Which symptom is most commonly associated with larger ventricular septal defects (VSDs)?

<p>Fatigue (B)</p> Signup and view all the answers

What is a common consequence of untreated patent ductus arteriosus (PDA)?

<p>Pulmonary hypertension (C)</p> Signup and view all the answers

What physiological change is observed in the heart due to a significant coarctation of the aorta?

<p>Decreased blood flow to the upper body (D)</p> Signup and view all the answers

What kind of defect can lead to pulmonary hypertension and right-sided heart enlargement over time?

<p>Ventricular septal defect (C)</p> Signup and view all the answers

Which embryological defect can lead to dextrocardia?

<p>Interference with left-right axis determination (B)</p> Signup and view all the answers

What effect does a large ventricular septal defect have on the heart's output?

<p>Increased shunting of blood from left to right (A)</p> Signup and view all the answers

What clinical feature is typically observed in patients with large patent ductus arteriosus?

<p>Left ventricular hypertrophy (B)</p> Signup and view all the answers

Which factor is NOT associated with the development of embryological heart defects?

<p>Improper fetal positioning (B)</p> Signup and view all the answers

Flashcards

Interatrial Septum

Divides the right and left atria of the heart.

Interventricular Septum

Divides the right and left ventricles of the heart.

SA Node

The heart's pacemaker; initiates electrical signals for contraction.

AV Node

Delays the electrical signal from the atria to the ventricles.

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AV Bundle

Conducts the electrical signal through fibrous skeleton to the ventricles.

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Purkinje Fibers

Specialized fibers that rapidly distribute the electrical signal throughout the ventricles.

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Right vs. Left Ventricle Myocardial Walls

Right ventricle has thinner, more trabeculated walls; left ventricle has thicker walls.

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Atrioventricular Valves

control blood flow between atria and ventricles (e.g., mitral/bicuspid vs. tricuspid)

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Heart Innervation

The heart receives nerve signals from the cardiac plexus, a network of both sympathetic and parasympathetic nerves.

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Cardiac Plexus Location

Located at the front of the trachea's division and behind the aorta & pulmonary trunk.

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Coronary Artery Function

The coronary arteries supply blood to the heart muscle (myocardium) and outer layer (epicardium).

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Coronary Artery Origin

Branches from the aorta, arising above its valve.

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Subendocardial Branches

Tiny branches in the heart's inner layer that deliver signals and nutrients to heart muscle cells.

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AV Node Blood Supply

The AV node receives blood from a branch of the posterior IV artery.

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Parasympathetic Nerve Source

The vagus nerves provide parasympathetic innervation to control heart rate.

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Endocardial Blood Supply

The inner heart lining (endocardium) gets oxygen and nutrients via diffusion or tiny blood vessels.

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Primary Heart Field (PHF)

The earliest region involved in heart development, located in the anterior lateral plate mesoderm. It forms part of the atria and the left ventricle.

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Secondary Heart Field (SHF)

Located adjacent to the PHF, contributing to the heart tube's elongation. It forms the right ventricle, outflow tracts, and parts of the atria.

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Cardiac Looping

The bending of the heart tube to form a looping structure, crucial for positioning heart chambers.

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Bulbus Cordis

Part of the heart tube that develops into the trabeculated portions of the right ventricle.

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Outflow Tract

The portion of the heart that forms the roots and proximal parts of the aorta and pulmonary artery. Part of the conus cordis and truncus arteriosus.

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Heart Tube Fusion

Endocardial heart tubes joining together in the 3rd week to form the primordial heart tube.

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Neural Crest Cells

Cells originating from the neural tube and contributing to the cardiac outflow tract and aorticopulmonary septum.

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Heart Tube Bending

A critical process during heart development; the looping of the heart tube into a C-shape

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Cardiac Development Process

The series of events forming the heart, from basic tissue arrangement to complex anatomy, including stages like folding and bending.

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Heart chamber formation

The development of the four chambers (right and left atria and ventricles) of the heart.

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Congenital Heart Defect

Structural abnormalities in the heart present at birth, often due to developmental issues, causing functional issues.

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Fetal Shunts

Specialized circulatory connections within a fetus, redirecting blood flow to bypass the lungs before birth; closing after birth.

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Embryonic Heart Tube

The early, simple tubular structure that gives rise to the heart of an embryo.

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Endocardial Cushions

Structures that take part in forming the heart valves and septa, crucial in completing heart development.

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Prenatal Heart Murmur

A sound heard within the heart during pregnancy, a possible clinical indicator. May or may not be considered significant.

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Vasculogenesis

The development of blood vessels in the embryo.

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Aortic Valve Location

Located at the 2nd right intercostal space, near the sternum.

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Umbilical Vein Function

Carries oxygenated blood to the embryo.

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Papillary Muscle Attachment

Attached to the chordae tendineae of atrioventricular valves.

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Mediastinum Subdivisions

The area in the chest containing the heart, major vessels, and other organs. Divided into superior and inferior sub-divisions (anterior, middle, posterior).

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Heart Position (Relative)

Located roughly 2/3rds to the left and 1/3rd to the right of the median plane.

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Mitral Valve Location (Auscultatory)

Located at the 5th intercostal space, midclavicular line (apex).

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Pericardium Function

Encloses the heart, anchors & protects, prevents overfilling, and provides low friction environment.

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Cardiac Structure & 2nd Right Intercostal Space

The aortic valve

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Parietal Layer

The inner lining of the pericardium, a sac surrounding the heart.

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Visceral Layer

The outer lining of the heart, also called the epicardium.

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Epicardium

The outermost layer of the heart wall; part of the visceral pericardium.

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Myocardium

Thick, middle layer of the heart wall, made of cardiac muscle.

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Endocardium

Inner lining of the heart chambers and valves.

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Cardiomyocytes

Individual cardiac muscle cells making up the myocardium.

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Purkinje Fibers

Specialized cardiac muscle fibers for rapid electrical signal conduction in the heart.

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Papillary Muscles

Ventricular muscles connected to AV valves by chordae tendineae.

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Sinus Venosus to Atria

Blood flows from the sinus venosus into the forming atria during early heart development.

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Endocardial Cushions Formation

Structures forming in the atrioventricular (AV) canal that divide it and assist in later heart valve formation around the end of the 4th week of development.

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Bulbus Cordis' Role

Part of the heart tube that develops into the trabeculated parts of the right ventricle and outflow tracts.

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Truncus Arteriosus Development

This heart structure evolves into the outflow tract of the heart, leading to the pulmonary trunk and aorta.

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Early Heart Blood Flow Path

Blood flows from the sinus venosus to the atrium, then the ventricle, and finally out the bulbus cordis and truncus arteriosus during early heart development.

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Intercalated Discs

Specialized junctions connecting cardiac muscle cells, containing desmosomes, gap junctions, and fascia adherens for cell-to-cell communication and force transmission during contraction.

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Cardiac Muscle Fibers

Striated, branched, and interconnected muscle cells in the heart, containing large mitochondria and sarcomeres, connected via intercalated discs.

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Fibrous Skeleton

Dense connective tissue framework of the heart, anchoring cardiac muscle fibers, supporting valves, and maintaining valve orifice patency.

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Endocardium Structure

The inner lining of the heart chambers and valves composed of simple squamous epithelium (endothelium), supporting connective tissue, small blood vessels, nerves, and Purkinje fibers.

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Gap junctions in heart

Structures that directly connect the cytoplasm of two cardiac muscle cells to allow for direct electrical signals propagation through the heart.

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Functional Syncytium

A single coordinated unit of cardiac muscle where cells function as a single unit due to gap junctions.

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Desmosomes in heart

Structures that hold cardiac cells firmly together to prevent separation due to contractions.

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Fascia adherens

Protein anchors that connect actin filaments, assisting in force transmission during heart muscle contractions.

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Larger VSDs Symptoms

Larger ventricular septal defects (VSDs) can cause symptoms like fatigue, difficulty breathing during exertion, rapid heartbeat, and repeated lung infections.

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VSD Cause

Ventricular septal defect (VSD) occurs when the wall separating the heart's lower chambers doesn't close completely, leading to left-to-right blood flow.

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PDA

Patent ductus arteriosus (PDA) is a congenital heart condition where the blood vessel connecting the aorta and pulmonary artery remains open after birth.

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Large PDA Effects

A large patent ductus arteriosus (PDA) diverts blood from the main artery (aorta) to the lung artery (pulmonary artery), causing a buildup of pressure and blood in the lungs.

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Coarctation of Aorta

A narrowing of the aorta, typically below the artery supplying the left arm. It can result in high blood pressure in the upper body, but lower blood pressure in the lower body.

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Embryological Defect Causes

Embryonic heart defects can result from problems with body axis development, precursor cell migration, or both.

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Left-right determination

A process in early embryonic development during which organs are determined if the organ will be located on the left or right side of the body.

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Improper Migration

If cells do not move to the correct place in the developing embryo, it can cause heart defects like VSDs or other anomalies.

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Related Documents

BMS 200 CV Embryology (1).pdf

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