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Questions and Answers

What is the purpose of using the toe-brachial index (TBI) in diagnosing peripheral artery disease (PAD)?

  • To evaluate blood flow in the toes (correct)
  • To measure blood pressure in the arm
  • To assess the risk of coronary artery disease
  • To determine the patient's overall fitness level

A decrease of 20% in the ankle-brachial index (ABI) after exercise is indicative of peripheral artery disease.

True (A)

What treatment is recommended for patients with peripheral artery disease showing symptoms and an ABI of 0.90 or less?

Aspirin, clopidogrel, or ticagrelor

The structured ________ program is an important part of treating peripheral artery disease.

<p>exercise</p> Signup and view all the answers

Match the following treatments with their effects on peripheral artery disease:

<p>Aspirin = Reduces downside events Statins = Decreases major adverse cardiovascular events (MACE) Cilostazol = Improves walking distance Rivaroxaban = Reduces MACE but increases bleeding risk</p> Signup and view all the answers

Which of the following is classified as a type of cancer?

<p>Leukemia (A)</p> Signup and view all the answers

Immunosuppressed hosts are at higher risk for fungal infections.

<p>True (A)</p> Signup and view all the answers

Name one disorder associated with calcium metabolism.

<p>Calcium Disorders</p> Signup and view all the answers

_____ is a chronic autoimmune disease characterized by inflammation of the joints.

<p>Rheumatoid Arthritis</p> Signup and view all the answers

Match the following types of pneumonia with their characteristics:

<p>Aspiration Pneumonia = Occurs when food or liquid enters the lungs Bacterial Pneumonia = Typically caused by bacteria such as Streptococcus pneumoniae Viral Pneumonia = Commonly caused by viruses, including influenza Fungal Pneumonia = Caused by fungal infections, often in immunocompromised individuals</p> Signup and view all the answers

Which of the following is a common side effect of chemotherapy?

<p>Nausea and vomiting (B)</p> Signup and view all the answers

Diabetes Mellitus can lead to increased risk of rheumatic diseases.

<p>True (A)</p> Signup and view all the answers

What is the primary concern in infections of the nervous system?

<p>Meningitis</p> Signup and view all the answers

What effect does dupilumab have on patients with severe asthma?

<p>Decreases exacerbations (A)</p> Signup and view all the answers

Yearly flu shots are recommended for patients with asthma to help manage their condition.

<p>True (A)</p> Signup and view all the answers

What is the goal for achieving complete control in asthma management?

<p>Daily symptoms ≤ 2/week, no nocturnal symptoms, reliever medication ≤ 2/week, normal peak expiratory flow rate or FEV1.</p> Signup and view all the answers

In asthma management, one can abort an exacerbation by quadrupling the __________ if control deteriorates.

<p>ICS</p> Signup and view all the answers

Match the asthma evaluation criteria with their descriptions:

<p>Prior intubation = Risk factor for life-threatening asthma Pulsus paradoxus = Physical exam finding Current exacerbation duration = Assessment criteria Hemodynamic instability = Contraindication for positive-pressure ventilation</p> Signup and view all the answers

Which method is NOT considered a contraindication for positive-pressure ventilation?

<p>Personal best PEF known (C)</p> Signup and view all the answers

Asthma treatments should be adjusted without the need for monitoring patient control levels.

<p>False (B)</p> Signup and view all the answers

What is a classic association with STE V1–V4?

<p>Right axis deviation (RAD) (A)</p> Signup and view all the answers

What is the significance of peak expiratory flow (PEF) monitoring in asthma management?

<p>It helps to determine personal best and assess asthma control.</p> Signup and view all the answers

Elevated ST segment in lead aVR greater than 1 mm is associated with decreased mortality in STEMI.

<p>False (B)</p> Signup and view all the answers

What is one indication for considering Noninvasive Positive Pressure Ventilation (NPPV)?

<p>Signs of increased work of breathing (B)</p> Signup and view all the answers

What is the main symptom of pneumonia?

<p>Pleuritic pain, dyspnea, fever, cough, sputum</p> Signup and view all the answers

Ventilator-associated pneumonia has a mortality rate of approximately 10%.

<p>False (B)</p> Signup and view all the answers

The condition characterized by sharp pleuritic pain and hyperresonance on examination is known as ___.

<p>pneumothorax</p> Signup and view all the answers

What is the clinical screening criteria for performing a spontaneous breathing trial (SBT)?

<p>Stable vital signs, minimal secretions, adequate cough.</p> Signup and view all the answers

Which of the following is NOT a symptom of esophageal reflux?

<p>Sharp pleuritic pain (A)</p> Signup and view all the answers

The recommended ventilator parameters for predicting failure include PaO2/FiO2 >200 and PEEP ≤ ____.

<p>5</p> Signup and view all the answers

What diagnostic tests are suggested for diagnosing esophageal spasm?

<p>Manometry</p> Signup and view all the answers

Which of the following pathogens is commonly associated with ventilator-associated pneumonia?

<p>MRSA (B)</p> Signup and view all the answers

Match the following terms with their associated descriptions:

<p>Ventilator-induced lung injury = Damage caused by mechanical ventilation Cuff leak test = Assessment for laryngeal edema Daily awakening trial = Assessment for sedation and readiness Enteral nutrition = Preferred over total parenteral nutrition in vented patients</p> Signup and view all the answers

Match the following conditions with their primary diagnostic procedure:

<p>Pneumonia = CXR infiltrate Peptic Ulcer Disease = EGD Mallory-Weiss = EGD Biliary Disease = RUQ U/S</p> Signup and view all the answers

Stress ulcer prophylaxis with PPI has shown a significant improvement in the overall course of patients.

<p>False (B)</p> Signup and view all the answers

The abnormal heart rhythm characterized by a downsloping ST segment in leads V1–V2 is known as ___.

<p>Brugada syndrome</p> Signup and view all the answers

What does the term 'acute ventilatory deterioration' refer to?

<p>A sudden worsening of a patient's respiratory function requiring immediate intervention.</p> Signup and view all the answers

What is the definition of left axis deviation (LAD)?

<p>Axis beyond -30° (B)</p> Signup and view all the answers

Right ventricular hypertrophy (RVH) always presents with left axis deviation.

<p>False (B)</p> Signup and view all the answers

Name one common etiology of left anterior fascicular block (LAFB).

<p>Left ventricular hypertrophy (LVH)</p> Signup and view all the answers

If the R wave in V3 is less than or equal to ______ mm, it indicates poor R wave progression.

<p>3</p> Signup and view all the answers

Match the following conditions with their defining characteristics:

<p>Left axis deviation (LAD) = Axis beyond -30° Right axis deviation (RAD) = Axis between 90° and 180° Left posterior fascicular block (LPFB) = S in I &amp; aVL, qR in III &amp; aVF Right ventricular hypertrophy (RVH) = R &gt; S in V1</p> Signup and view all the answers

Which of the following is a criterion for right ventricular hypertrophy (RVH)?

<p>R in aVR ≥ 4 mm (B)</p> Signup and view all the answers

A small (septal) q wave in lead I is considered abnormal.

<p>False (B)</p> Signup and view all the answers

What does ST elevation in the context of acute myocardial infarction typically look like?

<p>Upward convexity (a 'frown')</p> Signup and view all the answers

The Romhilt-Estes point-score system states that if left anterior fascicular block (LAFB) is present, the S wave in III plus the maximum R + S in any lead must be at least ______ mm in men or ______ mm in women.

<p>30, 28</p> Signup and view all the answers

Which of the following conditions is typically NOT associated with ST elevation?

<p>Severe bradycardia (A)</p> Signup and view all the answers

Flashcards

What is anemia?

Anemia is characterized by a decrease in the number of red blood cells or hemoglobin in the blood, leading to inadequate oxygen delivery to tissues.

What are platelet disorders?

Platelet disorders involve abnormalities in the number or function of platelets, which are crucial for blood clotting. These disorders increase the risk of bleeding.

What are coagulopathies?

Coagulopathies are a group of disorders characterized by abnormal blood clotting, leading to an increased risk of both bleeding and thrombosis (blood clots).

What are hypercoagulable states?

Hypercoagulable states are conditions where the blood is more likely to clot, increasing the risk of thrombosis (blood clots) in the blood vessels.

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What are disorders of leukocytes?

Disorders of leukocytes, also known as white blood cells, involve abnormalities in the number or function of these cells, which are essential for fighting infections. These disorders can compromise the immune system and increase susceptibility to infections.

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What is transfusion therapy?

Transfusion therapy involves the administration of blood or blood products to replace lost blood or correct blood disorders.

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What are myelodysplastic syndromes?

Myelodysplastic syndromes are a group of disorders that involve the abnormal development of bone marrow cells, leading to a decreased production of healthy blood cells.

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What are myeloproliferative neoplasms?

Myeloproliferative neoplasms involve the uncontrolled growth of blood cells in the bone marrow, leading to an overproduction of certain blood cells.

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What is the ABI?

The ankle-brachial index (ABI) is a measure of blood flow in the lower limbs, calculated by dividing the ankle systolic blood pressure by the brachial systolic blood pressure. It is a common test for PAD.

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What should be done if the ABI is abnormal?

If the ABI is abnormal, segmental ABI with pulse volume recording should be performed to localize PAD.

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What to do if someone has PAD symptoms but a normal ABI?

If there are positive symptoms for PAD, such as claudication, but a normal ABI, then look for a decrease in lower extremity blood pressure after exercise.

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What is the first line of treatment for managing PAD?

Risk factor modification for PAD entails addressing factors like smoking, diabetes, hypertension, and hyperlipidemia.

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What drug therapy is recommended for symptomatic PAD patients?

Patients with PAD who are symptomatic or asymptomatic with an ABI ≤ 0.90 should receive antiplatelet therapy to reduce the risk of death, MI, and stroke.

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Severe Asthma with Eosinophilia (SAwE)

A type of asthma where eosinophils are elevated in the airways.

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Dupilumab

A monoclonal antibody that blocks the actions of interleukin-4 and interleukin-13, used in the treatment of severe asthma.

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Yearly Flu Shot for Asthma Patients

Yearly vaccinations against the influenza virus are recommended for all asthma patients.

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Rescue Medication for Asthma

A quick-relief medication used to relieve asthma symptoms as needed.

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Quadrupling ICS for Asthma Exacerbation

Using a higher dose of inhaled corticosteroids (ICS) to quickly control a worsening asthma episode.

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Peak Expiratory Flow (PEF)

A measure of lung function, used to assess asthma severity and control.

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Positive-Pressure Ventilation for Asthma

A non-invasive ventilation technique to support breathing in patients with severe asthma.

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Endotracheal Intubation for Asthma

A procedure used to assist breathing in patients with severe asthma, involves inserting a tube into the trachea.

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STE V1-V3 + TWI V1-V4

ST elevation (STE) in leads V1-V3, often associated with T wave inversion (TWI) in leads V1-V4, right axis deviation (RAD), right bundle branch block (RBBB), and S1Q3T3 pattern. Suggestive of a STEMI (ST-segment elevation myocardial infarction).

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STE in aVR

Elevated ST segment in lead aVR, often associated with increased mortality in STEMI. Also indicates left main disease if STE in aVR is greater than STE in V1.

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LBBB (Left Bundle Branch Block)

Increase in QRS duration, discordant ST elevation (STE) compared to the QRS complex. Consider this in the context of ACS (acute coronary syndrome) to differentiate from MI in LBBB (left bundle branch block).

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Elevated QRS Amplitude

Increased QRS amplitude, suggesting left ventricular hypertrophy (LVH).

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Brugada Syndrome

Characterized by typical ECG pattern of rightward ST elevation (rSR′) particularly in leads V1-V2 and downsloping ST segment in leads V1-V2. May lead to VT or sudden cardiac death.

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Early Repolarization

Elevated ST segments, particularly in V2-V5 in young adults. Often involves a notch or a slurred downstroke of the R wave (J point). May also have ST elevation and elevated T wave (Tw), leading to a high STE/Tw ratio.

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Pneumonia

Sharp, pleuritic pain, often associated with dyspnea, fever, cough and sputum. Chest X-ray typically shows an infiltrate.

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Pneumothorax

Sudden onset of sharp, pleuritic pain. Usually involves hyperresonance (increased air in the chest) and decreased breath sounds. Chest X-ray will show pneumothorax.

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Left Bundle Branch Block (LBBB)

A condition where the heart's electrical signals travel abnormally through the left ventricle. This can cause the QRS complex on the ECG to be wider than normal, and the electrical axis of the heart to shift to the left.

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Right Bundle Branch Block (RBBB)

A condition where the heart's electrical signals travel abnormally through the right ventricle. This can cause the QRS complex on the ECG to be wider than normal, and the electrical axis of the heart to shift to the right.

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Left Axis Deviation (LAD)

A condition where the heart's electrical axis is shifted to the left, beyond -30 degrees. This can be caused by a number of factors, including left ventricular hypertrophy, left bundle branch block and inferior myocardial infarction.

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Right Axis Deviation (RAD)

A condition where the heart's electrical axis is shifted to the right, beyond +90 degrees. This can be caused by a number of factors, including right ventricular hypertrophy, pulmonary embolism and COPD.

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Left Anterior Fascicular Block (LAFB)

A condition where the electrical signals travel abnormally through the left anterior fascicle, a part of the left bundle branch. This can cause a specific pattern on the ECG, with a left axis deviation and a qR pattern in aVL.

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Left Posterior Fascicular Block (LPFB)

A condition where the electrical signals travel abnormally through the left posterior fascicle, a part of the left bundle branch. This can cause a specific pattern on the ECG, with a right axis deviation and a rS pattern in I and aVL.

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Poor R Wave Progression (PRWP)

A pattern on the ECG that suggests a prior myocardial infarction. This pattern typically shows a loss of R wave progression in the precordial leads (V1-V3), an R wave in V3 that's less than 3mm, and sometimes persistent ST elevation.

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Hypertrophic Cardiomyopathy (HCM)

A condition in which the heart muscle is abnormally thickened. This can be caused by a number of factors, including genetic predisposition, high blood pressure and diabetes.

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Pulmonary Embolism (PE)

A condition in which a blood clot travels to the lungs, obstructing the blood flow through the pulmonary arteries.

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Ventricular Tachycardia (VT)

A condition in which the heart's electrical signals travel abnormally through the ventricles. This can cause a wide QRS complex on the ECG, and may be a sign of underlying heart disease.

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What is Noninvasive Positive Pressure Ventilation (NPPV)?

A type of mechanical ventilation where air pressure is delivered through a mask or nasal prongs, improving lung function and breathing.

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What is increased peak inspiratory pressure (PIP)?

An increase in the pressure required to deliver a breath, indicating potential lung problems.

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What is a spontaneous breathing trial (SBT)?

A period of time where the patient is disconnected from the ventilator to assess their ability to breathe independently.

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What is ventilator-induced lung injury (VILI)?

Inflammation of the lungs caused by the ventilator itself. It's a serious complication.

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What is ventilator-associated pneumonia (VAP)?

An infection of the lungs that develops in a person on mechanical ventilation.

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What is laryngeal edema?

A condition where the larynx swells due to prolonged intubation. It can lead to difficulty breathing.

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What is tracheostomy?

A surgical procedure to create a permanent opening into the windpipe, making breathing easier for long-term ventilation.

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What are proton pump inhibitors (PPIs)?

A type of drug used to prevent or treat stomach ulcers that can develop in critically ill patients.

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Study Notes

Book Title and Edition

  • Pocket Medicine, Seventh Edition
  • By Marc S. Sabatine
  • Published by Wolters Kluwer
  • Handbook of Internal Medicine

Book Content

  • Contains chapters on Cardiology, Pulmonary, Gastroenterology, Nephrology, Hematology-Oncology, Infectious Diseases, Endocrinology, Rheumatology, Neurology, and more.
  • Edited by Marc S. Sabatine, MD, MPH, Professor of Medicine at Harvard Medical School.
  • Book is a collaborative effort by several medical professionals.
  • Book has pages of content including index, and contributing authors.
  • Provides specific information about different medical conditions.

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Description

Test your knowledge on the diagnosis and treatment of various medical conditions, including peripheral artery disease, pneumonia, and autoimmune disorders. This quiz covers topics related to clinical assessments, treatment effects, and disease associations in a healthcare context.

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