Health Research Evidence Sources
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What are sources of evidence in health research? (List at least 5)

Peer-reviewed journal articles, Books, Conference proceedings, Government documents, Websites, Clinical practice guidelines, Experts' opinions.

Peer-reviewed journal articles are articles that have been published in scientific journals after being reviewed by other experts in the field.

True

Which of the following is NOT a benefit of peer-reviewed journal articles?

  • The peer-review process ensures the quality of the research and the validity of the results.
  • Online databases make it easy to look through tens of millions of articles.
  • They are easily accessible to a wider audience, including those without a paid subscription. (correct)
  • They provide information on very detailed topics and complicated analyses.
  • They can help to identify patterns or inconsistencies in research.
  • What are the limitations of peer-reviewed journal articles?

    <p>Users who are just looking for descriptive statistics and basic measures of public health may not need very detailed and complicated analyses. Articles may need a subscription to a journal or database to be accessed.</p> Signup and view all the answers

    Which of these options is NOT a type of gray literature?

    <p>Original research papers</p> Signup and view all the answers

    Why is gray literature often considered less reliable than peer-reviewed journal articles?

    <p>Gray literature is often not peer-reviewed, which means it has not been evaluated by experts in the field.</p> Signup and view all the answers

    Which type of study is considered the gold standard for evaluating the effectiveness of interventions or treatments?

    <p>Randomized Controlled Trials (RCTs)</p> Signup and view all the answers

    What is a major advantage of cohort studies?

    <p>They can assess multiple outcomes and examine rare exposures.</p> Signup and view all the answers

    What is the main difference between a prospective and a retrospective cohort study?

    <p>Prospective cohort studies start with a group of individuals without the outcome of interest and follow them over time, collecting data on exposures and tracking the occurrence of the outcome. Retrospective cohort studies use existing data to identify a group with a specific exposure and look back in time to determine the outcome status.</p> Signup and view all the answers

    Which type of study compares individuals with a specific outcome (cases) to a group without the outcome (controls) to investigate the potential association with exposures?

    <p>Case-control studies</p> Signup and view all the answers

    What is a strength of case-control studies?

    <p>They are useful for investigating rare diseases or outcomes with long latency periods.</p> Signup and view all the answers

    Which type of study collects data on exposures and outcomes at a single point in time from a representative sample of the population?

    <p>Cross-sectional studies</p> Signup and view all the answers

    What is a weakness of cross-sectional studies?

    <p>They cannot establish causality or temporal relationships.</p> Signup and view all the answers

    What is the difference between retrospective cohort studies and case-control studies?

    <p>Case-control studies compare a group without the complication to a group diagnosed with the complication. In retrospective cohort studies, we examine the exposure history of a group of people with the complication and the exposure history of a group without the complication and compare the two.</p> Signup and view all the answers

    What are case reports and why are they important?

    <p>Case reports are detailed descriptions of individual patients with unusual or noteworthy presentations or outcomes. They are valuable for generating hypotheses or identifying rare adverse events, but they do not provide strong evidence for causation due to their anecdotal nature.</p> Signup and view all the answers

    Why should expert opinions be considered in conjunction with higher levels of evidence?

    <p>Expert opinions can provide valuable insights based on their expertise, but they should be considered in conjunction with other forms of evidence, such as clinical trials or systematic reviews, to make informed clinical decisions.</p> Signup and view all the answers

    Which of the following is the MOST common journal paper for research data reports?

    <p>Original research</p> Signup and view all the answers

    Short reports or letters (sometimes called brief communications) are ideal for time-sensitive scientists in competitive or fast-changing fields because it is short.

    <p>True</p> Signup and view all the answers

    What is the purpose of narrative reviews?

    <p>Narrative reviews summarise research on a topic and discuss its current condition and future.</p> Signup and view all the answers

    Which of the following types of journal articles is NOT primarily focused on reporting specific instances of interesting phenomena?

    <p>Narrative reviews</p> Signup and view all the answers

    What is the purpose of methodologies or methods articles?

    <p>Methodologies or methods papers present new experimental methods, tests, or procedures that represent either entirely novel approaches or improvements upon existing methods.</p> Signup and view all the answers

    Which type of database contains references to published medical literature, such as research papers, books, and conference proceedings?

    <p>Bibliographic databases</p> Signup and view all the answers

    Which type of database contains information on clinical trials that are currently recruiting participants or that have been completed?

    <p>Clinical trial databases</p> Signup and view all the answers

    What is the purpose of patient databases?

    <p>Patient databases contain information on patients, such as their medical history, medications, and test results. They can be used to track patient outcomes and to identify patterns of disease.</p> Signup and view all the answers

    What does it mean for a journal to be indexed?

    <p>It means that the journal is included in a database that catalogues and indexes scholarly publications.</p> Signup and view all the answers

    Which of the following is NOT an advantage of open access journals?

    <p>They are typically more rigorous than subscription journals.</p> Signup and view all the answers

    What is a disadvantage of open access journals?

    <p>The cost of publishing in open access journals can be prohibitive for some authors.</p> Signup and view all the answers

    Which of the following statements is TRUE about the impact factor of a journal?

    <p>It is a measure of the frequency with which a journal's articles are cited in other research articles.</p> Signup and view all the answers

    The impact factor is a perfect measure of the quality of a journal.

    <p>False</p> Signup and view all the answers

    What are some other factors, besides the impact factor, that should be considered when evaluating the quality of a journal?

    <p>Other factors include the peer-review process, the reputation of the publisher, the journal's scope and focus, and the journal's adherence to ethical guidelines.</p> Signup and view all the answers

    What is the purpose of using quartiles to rank journals?

    <p>To understand how a journal ranks within its field based on its impact factor or other bibliometric measures.</p> Signup and view all the answers

    A journal being in Q1 means it is among the top 25% of journals in its category.

    <p>True</p> Signup and view all the answers

    What does it mean for a database to be "maintained by" a particular organization?

    <p>It means the organization is responsible for acquiring, organizing, storing, maintaining, and making the data available to authorized users.</p> Signup and view all the answers

    Study Notes

    Sources of Evidence

    •  Different sources of evidence in health research include peer-reviewed journal articles, books, conference proceedings, government documents, websites, clinical practice guidelines, and expert opinions.
    • Peer-reviewed articles are published in scientific journals after expert review.
    • Academic databases simplify the search for peer-reviewed literature across multiple journals.
    • Benefits of peer-reviewed articles include high quality and validity of research, detailed information on complex topics, and easy access through online databases.
    • Limitations include needing a subscription for access to articles, potential need for more in-depth analyses, and basic measures of public health not requiring the complexity of detailed analysis.

    Books

    •  Books can be a good source of information but need to be up-to-date and authored by experts.

    Conference Proceedings

    • Conference proceedings document presentations given at scientific conferences.
    • They can be a good source of new research but lack peer review.

    Government Documents

    • Government documents provide information on public health policy and guidelines.

    Websites

    •  Websites provide health research information but require careful evaluation of their reputation.

    Clinical Practice Guidelines

    • Documents with recommendations for the best ways to treat specific conditions.
    • Guidelines are based on the best available evidence and developed by experts in the field.

    Gray Literature

    •  Information not published in traditional academic journals or books.
    • Often not peer-reviewed, requiring careful evaluation.
    • Examples include government reports, technical reports, conference abstracts, newsletters, and reports, and websites.

    Hierarchy of Evidence

    •  A hierarchy of evidence exists, with randomized controlled trials (RCTs) considered the gold standard for evaluating interventions.
    • Levels of evidence range from systematic reviews and high-quality RCTs to case series and expert opinions.
    • The hierarchy reflects the strength of evidence supporting a particular conclusion.

    Levels of Evidence (based on a table)

    • Various levels exist for classifying strength of evidence based on type of studies (RCTs and others)

    Systematic Reviews and Meta-analyses

    • Involves identifying, selecting, and critically appraising relevant studies.
    • Synthesizes findings from multiple studies to create a comprehensive overview.
    • Meta-analysis is a statistical technique combining data to quantify overall effect size.

    Randomized Controlled Trials (RCTs)

    • RCTs are considered a gold standard for evaluating intervention effectiveness.
    • Participants are randomly assigned to intervention or control groups.
    • Randomization minimizes bias and ensures differences in outcomes are attributed to the intervention.
    • RCTs often use blinding to reduce researcher bias.

    Cohort Studies

    •  Follow a group of individuals over time to investigate exposures and outcomes.
    • Prospective cohort studies follow individuals without the outcome, observing exposures and outcomes over time.
    • Retrospective cohort studies use existing data to find those with a specific exposure and trace their outcomes in the past.
    • Cohort studies provide insights into incidence rates, exposures, and multiple outcomes but require long follow-up periods.

    Case-Control Studies

    • Compares individuals with and without a specific outcome to investigate associations with exposures.
    • Cases (with the outcome) and controls (without) are selected based on the presence or absence of exposure history.
    • Case-control studies are useful for rare diseases or outcomes but prone to recall bias.

    Cross-Sectional Studies

    • Collect data on exposures and outcomes from a representative sample at a single point in time.
    • Provide prevalence estimates and identify associations between variables, but cannot establish causality.

    Case Reports and Expert Opinions

    • Detailed descriptions of individual patients with unusual presentations or outcomes.
    • Can generate hypotheses or identify rare adverse events.
    • Expert opinions are valuable but should be considered with higher levels of evidence.

    Types of Journal Articles

    • Original Research: Common for reporting research findings with introduction, methods, results, and discussion sections.
    • Short Reports/Letters: Concise reports of new findings or insights suitable for fast-changing fields, often called brief communications.
    • Narrative Review: Summary of existing research on a particular topic focusing on current insights and future directions.
    • Case Studies: Descriptions of specific instances of interesting phenomena or conditions, intended to alert other researchers.
    • Methodologies/Methods: Descriptions of novel methods, test procedures, or experimental approaches.

    Databases

    • Bibliographic databases: Contain references to publications (research papers, books, conference proceedings). Useful for finding information on a particular topic.
    • Clinical trial databases: Contain information on current or completed clinical trials. Useful for locating relevant clinical trials.
    • Patient databases: Contain information on patient medical history, medications, and test results. Used for tracking patient outcomes and disease patterns.
    • Genetic databases: Contain information on genes such as their sequence and location.
    • Imaging databases: Contain images of medical scans including X-rays, MRIs, and CT scans.
    • Drug databases: Contain data on drugs, such as side effects and interactions.

    What does "maintained by" mean?

    •  When a database is "maintained by" an organization, that organization is responsible for acquiring data, organizing the data, storing the data, maintaining the data, and making it available to authorized users.

    Indexing

    • A journal is indexed when it's included in a database that catalogues and indexes scholarly publications.
    • Indexed journals' articles are easily searchable (for researchers).

    Impact Factor and Quartiles

    • Impact factor (IF) measures the frequency with which a journal's articles are cited by other research papers.
    • IF is calculated by dividing total citations in two preceding years by the number of citable articles in the same period.
    • It's a measure of journal quality, but limitations exist as citations vary by importance, impact factor captures relatively recent impact not long-term impact, and it's an average therefore can be misleading.
    • Quartiles (Q1-Q4) rank journals based on IF or other bibliometric measures categorizing journals according to their impact factor relative to others in their field.

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    Description

    Explore various sources of evidence utilized in health research. This quiz covers peer-reviewed articles, books, conference proceedings, and more, providing insights into their benefits and limitations. Test your knowledge on how to effectively utilize these resources in health research.

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