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HCG in Clinical Practice

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Questions and Answers

What is the principle of pregnancy detection using urine?

Detection of ∝- and ß-subunits (intact hCG/ fragments)

Detection of ß-subunit and intact HCG

Bioassay (correct)

Immunometric (sandwich) assays

Which of the following is a clinical utilization of HCG?

Treating Ectopic Pregnancy

Diagnosing Down Syndrome

Preventing Regression of Corpus Luteum

Detecting Gestational Trophoblastic Diseases (correct)

When can pregnancy be detected in serum using immunometric (sandwich) assays?

2-3 days after ovulation

Immediately after ovulation

Only after the first missed menses

6-12 days after ovulation (correct)

Which hormone is synthesized and secreted by trophoblast cells?

HCG Signup and view all the answers

What is the detection limit for pregnancy using immunometric (sandwich) assays in urine?

20 mIU/mL Signup and view all the answers

Which of the following is NOT a clinical utilization of HCG?

Prevents regression of corpus luteum Signup and view all the answers

What is the earliest assay for hCG determination?

Bioassay using animals for testing Signup and view all the answers

Which hormone has a larger molecular size compared to LH, FSH, and TSH?

HCG Signup and view all the answers

When can pregnancy be detected in urine using immunometric (sandwich) assays?

2-3 days after ovulation Signup and view all the answers

What is the detection limit for pregnancy using immunometric (sandwich) assays in serum?

1-2 mIU/mL Signup and view all the answers