HCG in Clinical Practice
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Questions and Answers

What is the principle of pregnancy detection using urine?

  • Detection of ∝- and ß-subunits (intact hCG/ fragments)
  • Detection of ß-subunit and intact HCG
  • Bioassay (correct)
  • Immunometric (sandwich) assays

Which of the following is a clinical utilization of HCG?

  • Treating Ectopic Pregnancy
  • Diagnosing Down Syndrome
  • Preventing Regression of Corpus Luteum
  • Detecting Gestational Trophoblastic Diseases (correct)

When can pregnancy be detected in serum using immunometric (sandwich) assays?

  • 2-3 days after ovulation
  • Immediately after ovulation
  • Only after the first missed menses
  • 6-12 days after ovulation (correct)

Which hormone is synthesized and secreted by trophoblast cells?

<p>HCG (D)</p> Signup and view all the answers

What is the detection limit for pregnancy using immunometric (sandwich) assays in urine?

<p>20 mIU/mL (A)</p> Signup and view all the answers

Which of the following is NOT a clinical utilization of HCG?

<p>Prevents regression of corpus luteum (A)</p> Signup and view all the answers

What is the earliest assay for hCG determination?

<p>Bioassay using animals for testing (A)</p> Signup and view all the answers

Which hormone has a larger molecular size compared to LH, FSH, and TSH?

<p>HCG (A)</p> Signup and view all the answers

When can pregnancy be detected in urine using immunometric (sandwich) assays?

<p>2-3 days after ovulation (C)</p> Signup and view all the answers

What is the detection limit for pregnancy using immunometric (sandwich) assays in serum?

<p>1-2 mIU/mL (C)</p> Signup and view all the answers

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