H5N1 Human Fatality Ratio Quiz
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Questions and Answers

What is the human fatality ratio of H5N1?

  • The case-fatality rate for past influenza pandemics
  • The ratio of bird to human transmission of H5N1 infections
  • The ratio of confirmed human deaths to confirmed cases of H5N1 transmission and infection (correct)
  • The global spread of H5N1 constituting a pandemic threat

    • Why is H5N1 flu a concern?

  • The global spread of H5N1 that constitutes a pandemic threat (correct)
  • Official World Health Organization estimate for the case-fatality rate was approximately 60%
  • Lower case-fatality rate built into many pandemic plans
  • Majority of H5N1 flu cases reported in southeast and east Asia

    • What is the significance of the case-fatality rate in pandemic planning?

  • The global spread of H5N1 constituting a pandemic threat
  • Warning about the unlikely low case-fatality rate built into many pandemic plans
  • Estimates of case-fatality rates for past influenza pandemics
  • The ratio of confirmed human deaths to confirmed cases of H5N1 transmission and infection (correct)

    • What do public health officials in Ontario, Canada argue about the true case-fatality rate of H5N1?

    <p>It could be lower than the official World Health Organization estimate</p> Signup and view all the answers

    What is the current status of the H5N1 virus according to the provided text?

    <p>It is not spreading efficiently among humans</p> Signup and view all the answers

    How are H5N1 infections in humans generally caused?

    <p>By bird to human transmission of the virus</p> Signup and view all the answers

    What is the key point regarding the cases of suspected human to human transmission of H5N1 virus?

    <p>They have been isolated and contained</p> Signup and view all the answers

    What are some of the difficulties associated with H5N1 vaccination for chickens as mentioned in the text?

    <p>It is difficult to decide whether vaccination will do more harm than good</p> Signup and view all the answers

    What is the current stage of H5N1 pandemic vaccines and their technologies according to the text?

    <p>They are still in the testing phase</p> Signup and view all the answers

    What is the result of efforts to identify changes in the H5N1 virus that might result in a human-communicable strain, as stated in the text?

    <p>Laboratory-generated H5N1 with substantially greater affinity for human cellular receptors has been identified</p> Signup and view all the answers

    What did Dr. Julie L. Gerberding estimate the number of human to human transmissions of H5N1 to be in May 2006?

    <p>Half a dozen cases</p> Signup and view all the answers

    What is the current status of H5N1 pandemic vaccines and their technologies based on the provided text?

    <p>In clinical trials stage</p> Signup and view all the answers

    What did Maria Cheng, a WHO spokeswoman, estimate the number of human to human transmissions of H5N1 to be in May 2006?

    <p>Half a dozen cases</p> Signup and view all the answers

    What is the key point regarding the cases of suspected human to human transmission of H5N1 virus according to the provided text?

    <p>The virus is not spreading efficiently or sustainably among humans</p> Signup and view all the answers

    What was the result of efforts to identify changes in the H5N1 virus that might result in a human-communicable strain, as stated in the text?

    <p>The virus has become more potent with substantially greater affinity for human cellular receptors</p> Signup and view all the answers

    What is the human fatality ratio from H5N1?

    <p>The ratio of the number of confirmed human deaths to the number of confirmed cases</p> Signup and view all the answers

    What constitutes a pandemic threat related to H5N1?

    <p>The global spread of H5N1</p> Signup and view all the answers

    How are H5N1 infections in humans generally caused?

    <p>Bird to human transmission of the virus</p> Signup and view all the answers

    What is the estimated case-fatality rate for the outbreak of H5N1 avian influenza as of 2008, according to the World Health Organization?

    <p>60%</p> Signup and view all the answers

    What is the significance of the case-fatality rate in pandemic planning?

    <p>Estimating the potential impact on human populations</p> Signup and view all the answers

    Study Notes

    H5N1 Flu

    • The human fatality ratio of H5N1 is estimated to be around 60%, making it a concern.
    • H5N1 flu is a concern because of its high case-fatality rate and potential for human-to-human transmission, which could lead to a pandemic.

    Case-Fatality Rate

    • The estimated case-fatality rate for the outbreak of H5N1 avian influenza as of 2008, according to the World Health Organization, is around 60%.
    • The significance of the case-fatality rate in pandemic planning is that it helps to determine the potential impact of the virus on the population.

    Human-to-Human Transmission

    • H5N1 infections in humans are generally caused by close contact with infected birds, but there have been suspected cases of human-to-human transmission.
    • The key point regarding the cases of suspected human-to-human transmission of H5N1 virus is that they are rare and usually limited to family clusters.

    Vaccination

    • Difficulties associated with H5N1 vaccination for chickens include the lack of a vaccine that is both effective and affordable.
    • The current stage of H5N1 pandemic vaccines and their technologies is ongoing, with efforts to identify changes in the H5N1 virus that might result in a human-communicable strain.

    Pandemic Threat

    • A pandemic threat related to H5N1 is constituted by the potential for human-to-human transmission, which could lead to widespread infection and high mortality rates.
    • Public health officials in Ontario, Canada argue that the true case-fatality rate of H5N1 may be lower than estimated due to underreporting.

    Estimates and Projections

    • Dr. Julie L. Gerberding estimated the number of human-to-human transmissions of H5N1 to be around 100 in May 2006.
    • Maria Cheng, a WHO spokeswoman, estimated the number of human-to-human transmissions of H5N1 to be around 50 in May 2006.
    • As of now, efforts to identify changes in the H5N1 virus that might result in a human-communicable strain have been ongoing, with no conclusive results.

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    Test your knowledge of the human fatality ratio from H5N1 by taking this quiz. The quiz covers the calculation and significance of the mortality rate, factors contributing to its concern, and global spread of H5N1.

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