Podcast
Questions and Answers
What is the primary factor that determines the success of reduced-intensity allogeneic stem cell transplantation?
What is the primary factor that determines the success of reduced-intensity allogeneic stem cell transplantation?
- High-dose treatments
- Graft-versus-tumor effect (correct)
- Donor's age
- Organ complications
In reduced-intensity allogeneic stem cell transplantation, what is the goal of having the donor stem cells take up residence in the recipient's marrow?
In reduced-intensity allogeneic stem cell transplantation, what is the goal of having the donor stem cells take up residence in the recipient's marrow?
- To replace the patient's immune system
- To produce cancer cells
- To attack the patient's remaining blood-cancer cells (correct)
- To kill the cancer cells with high-dose treatments
What is done in a 'donor lymphocyte infusion' (DLI) when there is mixed chimerism in reduced-intensity allogeneic transplantation?
What is done in a 'donor lymphocyte infusion' (DLI) when there is mixed chimerism in reduced-intensity allogeneic transplantation?
- An injection of the donor's lymphocytes (correct)
- An infusion of chemotherapy drugs
- An injection of the recipient's lymphocytes
- A procedure to remove donor lymphocytes
What is a potential risk associated with reduced-intensity allogeneic transplantations?
What is a potential risk associated with reduced-intensity allogeneic transplantations?
What term is used to describe a state where the donor's immune system does not completely replace that of the patient?
What term is used to describe a state where the donor's immune system does not completely replace that of the patient?
What potential effect does a 'donor lymphocyte infusion' (DLI) have on the immune system in reduced-intensity allogeneic transplantation?
What potential effect does a 'donor lymphocyte infusion' (DLI) have on the immune system in reduced-intensity allogeneic transplantation?
Why might a patient be given an injection of the donor's lymphocytes in reduced-intensity allogeneic transplantation?
Why might a patient be given an injection of the donor's lymphocytes in reduced-intensity allogeneic transplantation?
