GVHD Prevention and Medications Quiz
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Questions and Answers

What is the primary factor that determines the success of reduced-intensity allogeneic stem cell transplantation?

  • High-dose treatments
  • Graft-versus-tumor effect (correct)
  • Donor's age
  • Organ complications

    • In reduced-intensity allogeneic stem cell transplantation, what is the goal of having the donor stem cells take up residence in the recipient's marrow?

  • To replace the patient's immune system
  • To produce cancer cells
  • To attack the patient's remaining blood-cancer cells (correct)
  • To kill the cancer cells with high-dose treatments

    • What is done in a 'donor lymphocyte infusion' (DLI) when there is mixed chimerism in reduced-intensity allogeneic transplantation?

  • An injection of the donor's lymphocytes (correct)
  • An infusion of chemotherapy drugs
  • An injection of the recipient's lymphocytes
  • A procedure to remove donor lymphocytes

    • What is a potential risk associated with reduced-intensity allogeneic transplantations?

    <p>Patient's body rejecting the donated stem cells</p> Signup and view all the answers

    What term is used to describe a state where the donor's immune system does not completely replace that of the patient?

    <p>'Mixed chimerism'</p> Signup and view all the answers

    What potential effect does a 'donor lymphocyte infusion' (DLI) have on the immune system in reduced-intensity allogeneic transplantation?

    <p>Improves engraftment and antitumor effects</p> Signup and view all the answers

    Why might a patient be given an injection of the donor's lymphocytes in reduced-intensity allogeneic transplantation?

    <p>To improve engraftment and immune response</p> Signup and view all the answers

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