7 Questions
What is the primary factor that determines the success of reduced-intensity allogeneic stem cell transplantation?
Graft-versus-tumor effect
In reduced-intensity allogeneic stem cell transplantation, what is the goal of having the donor stem cells take up residence in the recipient's marrow?
To attack the patient's remaining blood-cancer cells
What is done in a 'donor lymphocyte infusion' (DLI) when there is mixed chimerism in reduced-intensity allogeneic transplantation?
An injection of the donor's lymphocytes
What is a potential risk associated with reduced-intensity allogeneic transplantations?
Patient's body rejecting the donated stem cells
What term is used to describe a state where the donor's immune system does not completely replace that of the patient?
'Mixed chimerism'
What potential effect does a 'donor lymphocyte infusion' (DLI) have on the immune system in reduced-intensity allogeneic transplantation?
Improves engraftment and antitumor effects
Why might a patient be given an injection of the donor's lymphocytes in reduced-intensity allogeneic transplantation?
To improve engraftment and immune response
Test your knowledge on medications used to prevent graft-versus-host disease (GVHD) and the two main categories of GVHD: acute and chronic. Learn about common medications like Methotrexate, Corticosteroids, and more.
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