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What type of carbohydrate is guar gum classified as?
What type of carbohydrate is guar gum classified as?
Which of the following components make up guar gum?
Which of the following components make up guar gum?
Which of these is described as a safe alternative to guar gum?
Which of these is described as a safe alternative to guar gum?
What type of linkages are found in the structure of guar gum?
What type of linkages are found in the structure of guar gum?
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What differentiates guar gum from typical dietary fibers?
What differentiates guar gum from typical dietary fibers?
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What was done to the trunk of the box?
What was done to the trunk of the box?
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How was oleoresin removed from the box?
How was oleoresin removed from the box?
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What happened to the oleoresin after it was collected?
What happened to the oleoresin after it was collected?
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Why was the length of the box increased over time?
Why was the length of the box increased over time?
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What is a likely characteristic of the oleoresin collected?
What is a likely characteristic of the oleoresin collected?
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What is the primary method mentioned for obtaining juice from the plant?
What is the primary method mentioned for obtaining juice from the plant?
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What happens to the juice after it is obtained from the plant?
What happens to the juice after it is obtained from the plant?
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What can be inferred about the residue mentioned after obtaining juice from the plant?
What can be inferred about the residue mentioned after obtaining juice from the plant?
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Which term describes the material obtained after the juice is dried?
Which term describes the material obtained after the juice is dried?
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What is predominantly retained after the juice is extracted from the plant?
What is predominantly retained after the juice is extracted from the plant?
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What is the appearance of gelatin?
What is the appearance of gelatin?
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Which of the following statements about gelatin is true?
Which of the following statements about gelatin is true?
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Which of these characteristics does gelatin NOT possess?
Which of these characteristics does gelatin NOT possess?
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What form can sheet gelatin take?
What form can sheet gelatin take?
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What best describes the odor and taste of gelatin?
What best describes the odor and taste of gelatin?
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What is the primary function of guar in relation to cholesterol levels?
What is the primary function of guar in relation to cholesterol levels?
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What property allows the substance to be used as an antiseptic?
What property allows the substance to be used as an antiseptic?
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How does the thickening power of guar compare to starch?
How does the thickening power of guar compare to starch?
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Which viruses are mentioned in relation to the substance's effects?
Which viruses are mentioned in relation to the substance's effects?
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In which industry is guar predominantly used due to its properties?
In which industry is guar predominantly used due to its properties?
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What is an effect of the substance on the skin?
What is an effect of the substance on the skin?
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What mechanism is suggested for guar's cholesterol-lowering effect?
What mechanism is suggested for guar's cholesterol-lowering effect?
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What is a characteristic feature of guar compared to starch in food applications?
What is a characteristic feature of guar compared to starch in food applications?
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Which pH property is associated with the mode of action of the substance on skin?
Which pH property is associated with the mode of action of the substance on skin?
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What condition is associated with inflammation of the eye that the substance can address?
What condition is associated with inflammation of the eye that the substance can address?
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Study Notes
Unorganized Drugs
- Definition: Mixtures of chemical substances or decomposition products of substances found in the biological source of the drug.
- Source: Derived from parts of plants or animals (through processes like incision, decoction, and expression).
- Forms: Solid to semisolid, some are fluids like oils or balsams.
- Description: Lacks cellular structure; identified through physical characteristics (form, color, fracture), solubility, and chemical tests.
Classification
-
Resins & Resin Combinations: Large organic aids for protection.
- Resins: Colophony, Guiacum
- Oleoresins: Mastic, Copaiba, Canada Turpentine
- Oleogumresins: Myrrh, Asafoetida
- Balsams: Benzoin, Balsam Peru
- Gums: Polysaccharides. Examples: Acacia, Tragacanth, Guar
- Dried Extracts: Agar, Gelatin
- Dried Juices: Aloes
- Dried Latex: Opium (milky exudate, emulsion or suspension).
- Oils & Fats
- Saccharine Substances : Honey
Resin vs. Gum
Feature | Resin | Gum |
---|---|---|
Nature | Mixture of organic compounds, mainly acids (solid or highly viscous) | Heteropolysaccharide polymers |
Production in plant | Natural or pathological; collected by incision | Pathological; produced after incision |
Solubility | Soluble in alcohol, organic solvents; insoluble in water | Soluble in hot water; insoluble in alcohol |
Function for plant | Protection (often with antimicrobial activity) | Protection against exudation of plant constituents from injured parts |
Resins and Resin Combinations
- General Characters: Hard, solid or semisolid, amorphous organic substance of complex nature.
- Insoluble in water, mostly insoluble in petroleum ether, but soluble in alcohol, chloroform, ether, and many organic solvents, as well as fixed and volatile oils and chloral hydrate.
- Forms solutions; on evaporation, deposit as a varnish-like film.
- Upon heating, soften and melt; burn with a smoky flame.
Occurrence
- Pure Resin
- Resin + volatile oils → oleoresins
- Resin + gums → gum-resins
- Resin + oil + gum → oleo-gum-resins
- Resin + sugar → glycosidal resin
How to Obtain Resin
- Extraction with ethanol and precipitation in water.
- Plant punctures
- Heating
- Distillation to separate volatile oil from oleoresin (secondary flow is produced from injury, primary flow is produced without injury).
- Box method (cutting into the trunk)
- Cup and gutter method (incisions, cups to collect).
Boswellia (Frankincense)
- Names: Frankincense
- Botanical Origin: Oleogum resin from Boswellia serrata
- Active Constituents: Boswellic acid isomers, volatile oil (p-cymene and thujene)
- Uses: Anti-inflammatory (osteoarthritis), anticancer, antiasthmatic (in Ayurveda).
Dosage (Boswellia)
- 300-400 mg of a standardized extract (containing 60% boswellic acids) three times daily is suggested.
Oleogum Resin: Myrrh
- Names: MyrrhGum Myrrh
- Botanical Origin: Oleogum-resin, obtained from stems and branches of Commiphora molmol
- Active Constituents: Volatile oil (with cuminaldehyde and eugenol), ẞ and y-commiphoric acids, gum (galactose, arabinose, xylose)
Myrrh Uses
- Antimicrobial and antiulcer activities
- Externally used for hemorrhoids, bedsores, and wounds.
- Treatment for mild inflammatory skin problems (anti-inflammatory and anti-ulcer effects).
- Sesquiterpenes provide antibacterial, antifungal, and analgesic effects.
Benzoin (Balsam)
- Balsamic resin from the bark of Styrax species.
- Contains benzoic or cinnamic acids.
- Uses: Perfumes, incense, flavoring, laryngitis, bronchitis (inhalation), wound healing.
Gums
- Gum acacia; Gum tragacanth; Guar gum
Gum Acacia (Gum Arabic)
- Name: Gum Arabic
- Botanical Origin: Dried gummy exudation from Acacia senegal
- Composition: Polysaccharide exudate
Agar-Agar
- Names: Agar, Japanese Isinglass
- Botanical Origin: Dried mucilaginous substance prepared from Gelidium corneum (red algae)
- Properties: Insoluble in cold water, soluble in hot water. Contains Ca salt of polysaccharides; yields D-and L-galactose and sulfate ions (agarose and agaropectin).
- Agarose, a neutral galactose polymer, is responsible for agar's gel strength. Agaropectin is responsible for solution viscosity (sulphonated).
Dried Extracts
- Agar-Agar
- Gelatin
- Gambir or Catechu
Dried Juices (Aloe)
- Name: Aloes; aloe
- Botanical Origin: Solid residue from evaporated liquid of transversely cut leaves of Aloes species (Liliaceae family).
- Aloe Juice (comes spontaneous from incision of leaves—pericycle)
- Aloe-gel (pith—inside leaf tissues)
Aloetic Juice Constituents
- Aloin (major cathartic constituent): C-glycosides (barbaloin and isobarbaloin).
- Resin (Alosin): Purgative action, small amount of aloe-emodin
- Aloe-gel (mucilage): Saccharide containing glycoproteins, mucopolysaccharides, or polysaccharides of glucomannan.
Aloe Action and Uses
- Aloe gel has no laxative effect; used in cosmetics, topical products, and as a moisturizer/emollient.
- Antimicrobial and antifungal (tinea, Streptococcus, Shigella).
- Treatment for psoriasis (hydrophilic cream).
- Spermicide, chemo-preventive agent for cancer, and peptic ulcers.
- Stimulant purgative (aloe juice).
- Contains anthrones, more effective than anthraquinones as purgatives.
Dried Latex (Opium)
- Names: Gum Opium, Raw Opium (أفيون)
- Composition: Dried milky exudation from unripe Papaver somniferum capsules (Papaveraceae family)
- Quality: Judged by morphine content (minimum 9.5% anhydrous).
Opium Preparation and Collection
- Incising the unripe capsule to allow milky latex to ooze out.
- Scraping, kneading, and wrapping the latex in leaves for drying in the shade.
- Color changes from milky white to chocolate brown upon standing.
Opium Action and Uses
- Remedy for intolerable pain (post-operative, severe trauma).
- Relieves intense pain (cancer patients, angina pectoris).
- Increases the efficacy of anesthetics; reduces the dosage required; prevents shock.
- Preferred treatment for excessive diarrhea.
- Used for polyuria (especially true diabetes), reducing urine output and blood sugar.
Opium Addiction
- Highly addictive with physical and psychological dependence.
- Requires tolerance to maintain the same effect (increasing dosages over time).
- Withdrawal symptoms include nausea, tearing, yawning, chills, and sweating.
- Contains over 19 alkaloids combined with meconic acid (meconates); sometimes combined with sulfuric acid or free as the weak base narcotine.
- The presence of meconic acid serves as an indication of opium presence.
Chemical Tests
-
Agar-Agar: Soluble in hot water; insoluble in cold water, also reacts with BaCl2 (white precipitate, BaSO4). Agar + iodine, reddish color.
-
Gelatin: Insoluble in cold water, absorbs liquid; dissolves with heating and forms jelly, reduced gel strength with long boiling. A test with picric acid yields canary yellow precipitate. A test with CuSO4 and NaOH produces violet color (Biurette test).
-
Opium/Glycosides: Modified Borntrager’s test for C-glycosides (filtration with benzene, a ferric chloride solution—oxidizes anthrone to anthraquinone, further treated with HCl and ammonium hydroxide to indicate a cherry-red color in benzene layer).
-
Meconic Acid: To an aqueous solution of meconic acid, add ferric chloride for coloration; blood-red.
-
Oils and Fats, Saccharine Substances are not listed here.
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Description
Test your knowledge on guar gum and oleoresin with this quiz. Explore the characteristics, structure, and extraction processes related to these substances. This quiz covers essential concepts that differentiate them from typical dietary fibers and their uses.