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PHY-C Growth Hormone Regulation and Effects

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PHY-C Growth Hormone Regulation and Effects

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Questions and Answers

What percentage of GH circulates free in plasma?

~20%

~80%

~60% (correct)

~40%

In maximal stimulation, what changes in the GH pulsatile secretion pattern?

Frequency of pulses increases (correct)

Amplitude of pulses increases

Intensity of pulses increases

Duration of pulses increases

During which stage of sleep does GH pulsatile secretion occur?

Stages III & IV (correct)

Stage I

Stage II

REM sleep

What is the main effect of GH on adipose cells?

Lipolysis Signup and view all the answers

What is the main regulatory effect of somatostatin on growth hormone (GH) secretion?

Inhibits GH secretion by inhibiting the action of GHRH Signup and view all the answers

What effect does GHRH have on growth hormone (GH) secretion?

Stimulates GH secretion by activating somatotrophs cells Signup and view all the answers

Which hormone is responsible for mediating the growth-promoting action of growth hormone (GH)?

Insulin-like growth factor I & II (IGF-I & II) Signup and view all the answers

What induces the secretory burst of growth hormone (GH) at puberty?

Estrogens and testosterone Signup and view all the answers

What is the most common cause of acromegaly?

Excessive growth hormone (GH) secretion Signup and view all the answers

Which condition may result from multiple anterior pituitary hormone deficiencies?

Pituitary dwarfism Signup and view all the answers

What is the effect of GH deficiency in childhood if left untreated?

Pituitary dwarfism Signup and view all the answers

What is the outcome of a glucose suppression test in a patient with acromegaly?

GH levels remain high after glucose ingestion Signup and view all the answers