PHY-C Growth Hormone Regulation and Effects
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Questions and Answers

What percentage of GH circulates free in plasma?

  • ~20%
  • ~80%
  • ~60% (correct)
  • ~40%

In maximal stimulation, what changes in the GH pulsatile secretion pattern?

  • Frequency of pulses increases (correct)
  • Amplitude of pulses increases
  • Intensity of pulses increases
  • Duration of pulses increases

During which stage of sleep does GH pulsatile secretion occur?

  • Stages III & IV (correct)
  • Stage I
  • Stage II
  • REM sleep

What is the main effect of GH on adipose cells?

<p>Lipolysis (A)</p> Signup and view all the answers

What is the main regulatory effect of somatostatin on growth hormone (GH) secretion?

<p>Inhibits GH secretion by inhibiting the action of GHRH (C)</p> Signup and view all the answers

What effect does GHRH have on growth hormone (GH) secretion?

<p>Stimulates GH secretion by activating somatotrophs cells (D)</p> Signup and view all the answers

Which hormone is responsible for mediating the growth-promoting action of growth hormone (GH)?

<p>Insulin-like growth factor I &amp; II (IGF-I &amp; II) (D)</p> Signup and view all the answers

What induces the secretory burst of growth hormone (GH) at puberty?

<p>Estrogens and testosterone (C)</p> Signup and view all the answers

What is the most common cause of acromegaly?

<p>Excessive growth hormone (GH) secretion (A)</p> Signup and view all the answers

Which condition may result from multiple anterior pituitary hormone deficiencies?

<p>Pituitary dwarfism (A)</p> Signup and view all the answers

What is the effect of GH deficiency in childhood if left untreated?

<p>Pituitary dwarfism (C)</p> Signup and view all the answers

What is the outcome of a glucose suppression test in a patient with acromegaly?

<p>GH levels remain high after glucose ingestion (D)</p> Signup and view all the answers

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