Podcast
Questions and Answers
What is the purpose of atom economy in chemical processes?
What is the purpose of atom economy in chemical processes?
- To ensure most reactant atoms are incorporated into the final product. (correct)
- To maximize the energy produced in reactions.
- To increase the production of unwanted byproducts.
- To simplify the number of stages in any chemical synthesis.
Which synthesis method exemplifies poor atom economy?
Which synthesis method exemplifies poor atom economy?
- A multi-stage process generating numerous byproducts. (correct)
- Single stage process with one product.
- One-step synthesis with zero waste.
- Using stoichiometric amounts of all reactants.
What is an advantage of the greener synthesis developed by BHC Company for ibuprofen?
What is an advantage of the greener synthesis developed by BHC Company for ibuprofen?
- It incorporates a majority of reactant atoms into the final product. (correct)
- It generates large quantities of unwanted byproducts.
- It requires fewer reagents than traditional methods.
- It utilizes stoichiometric amounts of reactants.
Which of the following describes a single-stage process?
Which of the following describes a single-stage process?
In the context of ibuprofen synthesis, what does 'unwanted byproducts' refer to?
In the context of ibuprofen synthesis, what does 'unwanted byproducts' refer to?
What does a multi-stage process typically indicate regarding atom economy?
What does a multi-stage process typically indicate regarding atom economy?
What is the common characteristic of reactions with high atom economy?
What is the common characteristic of reactions with high atom economy?
What was a major challenge addressed in the development of the new synthesis for ibuprofen?
What was a major challenge addressed in the development of the new synthesis for ibuprofen?
What is the formula for calculating percent yield?
What is the formula for calculating percent yield?
Which metric specifically assesses the total waste generated relative to the product mass?
Which metric specifically assesses the total waste generated relative to the product mass?
What does atom economy measure?
What does atom economy measure?
What is the purpose of Process Mass Intensity (PMI)?
What is the purpose of Process Mass Intensity (PMI)?
How is atom utilization related to atom economy?
How is atom utilization related to atom economy?
Which metric assesses the environmental impacts throughout all stages of a product's life?
Which metric assesses the environmental impacts throughout all stages of a product's life?
What aspect does reaction mass efficiency (RME) mainly focus on?
What aspect does reaction mass efficiency (RME) mainly focus on?
Which of the following is NOT typically considered when assessing conventional metrics in chemistry?
Which of the following is NOT typically considered when assessing conventional metrics in chemistry?
What does a smaller E-factor indicate about a chemical process?
What does a smaller E-factor indicate about a chemical process?
Which reaction class is considered atom economic?
Which reaction class is considered atom economic?
Which of the following methods has a poor atom economy due to byproduct production?
Which of the following methods has a poor atom economy due to byproduct production?
The atom economy (AE) calculation is essential for evaluating what aspect of synthetic methodologies?
The atom economy (AE) calculation is essential for evaluating what aspect of synthetic methodologies?
How is the E-factor calculated?
How is the E-factor calculated?
Which type of reaction can potentially be carried out in water or ionic liquids?
Which type of reaction can potentially be carried out in water or ionic liquids?
What is a key characteristic of inherent atom economy in reactions?
What is a key characteristic of inherent atom economy in reactions?
What does the term 'green chemistry' primarily emphasize?
What does the term 'green chemistry' primarily emphasize?
Flashcards
Atom Economy
Atom Economy
The percentage of the total mass of reactants that is converted into the desired product. It measures the efficiency of a chemical reaction in terms of how much of the starting materials ends up as the desired product.
E-factor
E-factor
The mass of all waste generated during a chemical process divided by the mass of the desired product. A lower E-factor indicates a more environmentally friendly process.
Atom Utilization
Atom Utilization
Similar to atom economy, it measures the percentage of the total mass of products that is the desired product. It considers all the products formed, not just the reactants.
Reaction Mass Efficiency (RME)
Reaction Mass Efficiency (RME)
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Process Mass Intensity (PMI)
Process Mass Intensity (PMI)
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Life Cycle Assessment (LCA)
Life Cycle Assessment (LCA)
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Ecological Indicator/Footprint
Ecological Indicator/Footprint
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Single-Stage Process
Single-Stage Process
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Multi-Stage Process
Multi-Stage Process
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Good Atom Economy
Good Atom Economy
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Poor Atom Economy
Poor Atom Economy
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Greener Synthesis
Greener Synthesis
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Chemical Byproducts
Chemical Byproducts
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Convergent Synthesis
Convergent Synthesis
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Rearrangement Reaction
Rearrangement Reaction
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Addition Reaction
Addition Reaction
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Elimination Reaction
Elimination Reaction
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Substitution Reaction
Substitution Reaction
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Nucleophilic Reaction
Nucleophilic Reaction
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Study Notes
Green Chemistry Metrics
- E-factor: total waste (grams)/product (grams). This metric measures the amount of waste generated per unit of product. Higher values indicate greater waste.
- Atom utilization: (MW of desired product/MW of all products) x 100. This metric assesses how effectively atoms from reactants are incorporated into the desired product. High values indicate better atom economy.
- Reaction mass efficiency (RME): (mass of product C/(mass of A + mass of B)) x 100. This metric measures the efficiency of a reaction in producing the desired product from the input materials. Higher values indicate better efficiency.
- Process mass intensity (PMI): total mass of materials/mass of isolated product. This metric measures the total amount of materials used to create a product.
- Life Cycle Assessment (LCA): assessment of environmental impacts throughout a product's lifespan.
Conventional Metrics
- Percent yield: (actual yield/theoretical yield) x 100. This metric measures the efficiency of chemical reactions in producing a desired product.
Established Metrics in Green Chemistry
- Atom economy
- Atom utilization
Additional Metrics Used in Green Chemistry
- Process mass intensity
- Life cycle assessment
- Ecological indicator/ecological footprint
Atom Economy Example: Ibuprofen Synthesis
- In ibuprofen synthesis, most reactant atoms are incorporated into the desired product.
- This leads to low levels of unwanted byproducts
- There are also environmental benefits
Topics Covered
- Ecological indicator/ecological footprint
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