Gravimetric Analysis in Pharmaceutical Analysis Quiz

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Questions and Answers

Which method of analysis is based on determining the mass of a pure compound to which the analyte is chemically related?

  • Particulate Gravimetry
  • Loss on Drying
  • Gravimetric Analysis (correct)
  • Loss on Ignition

What is the purpose of Loss on Ignition?

  • To calculate the weight of a substance in a sample from the weight of another substance
  • To measure the weight of a substance in a sample
  • To determine the amount of volatile material driven off when a substance is ignited (correct)
  • To determine the amount of volatile material driven off when a substance is dried

What temperature range is used in Loss on Drying?

  • 110-120°C (correct)
  • 200-300°C
  • 100-200°C
  • 0-100°C

What is the first step in Particulate Gravimetry?

<p>Filtration or extraction of analyte from the sample (A)</p> Signup and view all the answers

What can be determined using Particulate Gravimetry?

<p>Total Suspended Solids in treated wastewater (B)</p> Signup and view all the answers

What is the purpose of Gravimetric Analysis in pharmaceutical analysis?

<p>To calculate the weight of a chemically equivalent amount of another substance (B)</p> Signup and view all the answers

What is the main difference between Loss on Ignition and Loss on Drying?

<p>Loss on Ignition measures the percentage of volatile material driven off when substance is ignited, while Loss on Drying measures the weight of a substance in a sample (A)</p> Signup and view all the answers

What is the first step in Particulate Gravimetry?

<p>Filtration or extraction of analyte from the sample (B)</p> Signup and view all the answers

What can be determined using Particulate Gravimetry?

<p>The amount of particulate form of analyte in a sample (C)</p> Signup and view all the answers

What is the temperature range used in Loss on Drying?

<p>110-120°C (C)</p> Signup and view all the answers

Which type of analysis is based on determining the weight of a substance in a sample from the weight of a chemically equivalent amount of some other substance?

<p>Gravimetric Analysis (C)</p> Signup and view all the answers

What is the purpose of Loss on Ignition?

<p>To measure the amount of volatile material driven off when a substance is ignited (A)</p> Signup and view all the answers

What is the temperature range used in Loss on Drying?

<p>110-120°C (B)</p> Signup and view all the answers

What is the first step in Particulate Gravimetry?

<p>Filtration or extraction of analyte from the sample (A)</p> Signup and view all the answers

What can be determined using Particulate Gravimetry?

<p>The total suspended solids in treated wastewater (D)</p> Signup and view all the answers

Flashcards

Gravimetric Analysis

A method of analysis based on determining the mass of a pure compound chemically related to the analyte.

Loss on Ignition (LOI)

To determine the amount of volatile material driven off when a substance is ignited.

Loss on Drying (LOD)

A process that uses a specific temperature range to measure the weight of a substance in a sample.

First Step in Particulate Gravimetry

Filtration or extraction of analyte from the sample.

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Purpose of Particulate Gravimetry

To measure the amount of particulate form of analyte in a sample.

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Gravimetric Analysis in Pharma

To calculate the weight of a chemically equivalent amount of another substance.

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LOI vs LOD

Loss on Ignition measures volatile material upon ignition; Loss on Drying measures weight after drying.

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Study Notes

Gravimetric Analysis

  • Gravimetric analysis is based on determining the mass of a pure compound to which the analyte is chemically related.
  • It is a type of analysis based on determining the weight of a substance in a sample from the weight of a chemically equivalent amount of some other substance.

Loss on Ignition

  • The purpose of Loss on Ignition is to determine the amount of volatile matter in a sample.
  • It is different from Loss on Drying in that it involves heating the sample to a higher temperature to remove any volatile matter.

Loss on Drying

  • The temperature range used in Loss on Drying is typically 100-150°C.
  • The purpose of Loss on Drying is to determine the amount of moisture in a sample.

Particulate Gravimetry

  • The first step in Particulate Gravimetry is to separate the particles from the sample.
  • Particulate Gravimetry can be used to determine the amount of a specific substance in a sample, such as the amount of a particular metal or compound.
  • It is used in pharmaceutical analysis to determine the purity of a substance.

Pharmaceutical Analysis

  • The purpose of Gravimetric Analysis in pharmaceutical analysis is to determine the purity of a substance.

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