Gout: Disease of Kings

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10 Questions

What happens to the polymorphonuclear cells when monosodium urate crystals are increased in number?

They engulf the crystals and their plasma membrane is disrupted, releasing cytokines and chemokines.

What is the typical duration of an acute gout attack?

Several days to a week

What is the most common feature of gout?

Inflammation, swelling, and severe pain in the affected joints and skin around

What is the likely outcome of untreated chronic gout?

Permanent joint stiffness, damage, and deformity

What is the most affected joint in gout?

Big toe (monarticular)

What happens to the joints over time if gout is left untreated?

They become more affected, especially the ankles, knees, fingers, wrists, and elbows (polyarticular)

What is characteristic of chronic gout?

Short breaks in between attacks

What is a common feature of gout in addition to inflammation and swelling?

Edema in and around the affected joint

What is the difference between acute and chronic gout?

The frequency and duration of attacks

What is the result of the release of cytokines and chemokines in gout?

Increased inflammation and swelling

This quiz covers the basics of gout, a systemic disease characterized by high levels of uric acid in the bloodstream, leading to inflammatory arthritis. Learn about the causes, symptoms, and effects of gout on the body. Test your knowledge of this complex condition!

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