60 Questions
Which medication is used in the treatment of prostate cancer?
Flutamide
Which medication is a direct arteriolar vasodilator?
Minoxidil
Which medication inhibits 17α-hydroxylase and 17,20-lyase enzymes?
Ketoconazole
Which medication blocks the androgen receptor and inhibits 17α-hydroxylase and 17,20-lyase enzymes?
Spironolactone
Which medication is used in the treatment of benign prostatic hyperplasia (BPH)?
Tamsulosin
Which medication can cause gynecomastia as an adverse effect?
Flutamide
Which medication can cause sexual dysfunction as an adverse effect?
Flutamide
Which medication can cause amenorrhea as an adverse effect?
Spironolactone
Which medication can cause scalp irritation and hair growth in unintended areas as adverse effects?
Minoxidil
Which medication can cause fluid retention and tachycardia as adverse effects?
Minoxidil
Which medication is used to stimulate ovulation and treat infertility due to anovulation?
Clomiphene
Which medication is associated with an increased risk of endometrial cancer?
Tamoxifen
Which medication is primarily used to treat osteoporosis and has a lower risk of endometrial cancer compared to tamoxifen?
Raloxifene
Which medication inhibits the peripheral conversion of androgens to estrogen and is used in the treatment of ER-positive breast cancer in postmenopausal females?
Anastrozole
Which type of hormone replacement therapy involves the addition of progestin to counteract the increased risk of endometrial cancer?
Hormone Replacement Therapy
Which medication is used to block the effects of androgens and is associated with adverse effects such as hypertension and hypokalemia?
Abiraterone
Which medication inhibits the conversion of testosterone to dihydrotestosterone (DHT) and is used in the treatment of benign prostatic hyperplasia (BPH) and male-pattern baldness?
Finasteride
Which medication is a nonsteroidal competitive inhibitor of androgen receptors and is used in the treatment of prostate cancer?
Bicalutamide
Which medication is used in polycystic ovary syndrome (PCOS) to treat hirsutism and amenorrhea by blocking androgen receptors and inhibiting 17α-hydroxylase and 17,20-lyase?
Spironolactone
Which form of contraception contains both progestins and ethinyl estradiol and prevents pregnancy by inhibiting LH/FSH release, preventing estrogen surge, ovulation, and endometrial proliferation?
Combined Contraception
Which hormone(s) do GnRH analogs modulate the secretion of?
Luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
Which type of administration of GnRH analogs is used for conditions like infertility?
Pulsatile administration (agonist)
Which type of administration of GnRH analogs is used in cancer treatment?
Continuous administration (antagonist)
Which GnRH analog acts as an antagonist without causing a start-up flare?
Degarelix
What are the clinical uses of GnRH analogs?
Uterine fibroids, endometriosis, precocious puberty, prostate cancer, infertility
What is the clinical use of Ethinyl Estradiol?
Hormone replacement therapy in postmenopausal females and treatment of menstrual abnormalities
What are the adverse effects associated with the use of Ethinyl Estradiol?
Increased risk of endometrial cancer, bleeding in postmenopausal patients, elevated risk of thrombi (blood clots)
What are the contraindications for the use of Ethinyl Estradiol?
ER-positive breast cancer, history of deep vein thrombosis (DVT), tobacco use in females over 35 years old
Which hormone(s) do GnRH analogs decrease the secretion of?
Luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
What is the mechanism of action of GnRH analogs?
Interact with the GnRH receptor in the pituitary gland
Which medication is used in the treatment of polycystic ovary syndrome (PCOS) to reduce androgen levels?
Spironolactone
Which medication is a nonsteroidal competitive inhibitor at the androgen receptor, preventing binding of androgens to the receptor?
Flutamide
Which medication is an α1-antagonist selective for α1A/D receptors in the prostate, leading to reduced smooth muscle tone and increased urine flow?
Tamsulosin
Which medication is a direct arteriolar vasodilator, used in the treatment of androgenetic alopecia (pattern baldness) and severe refractory hypertension?
Minoxidil
Which medication inhibits 17α-hydroxylase and 17,20-lyase enzymes, thus reducing steroid synthesis?
Ketoconazole
Which medication is associated with adverse effects such as gynecomastia and sexual dysfunction?
Flutamide
Which medication is used in the treatment of prostate cancer?
Bicalutamide
Which medication is used in the treatment of benign prostatic hyperplasia (BPH)?
Tamsulosin
Which medication is used in the treatment of androgenetic alopecia (pattern baldness)?
Minoxidil
Which medication is used in the treatment of severe refractory hypertension?
Minoxidil
Which medication is associated with an increased risk of thromboembolic events, especially in tobacco smokers?
Tamoxifen
Which medication is used primarily to treat osteoporosis and is associated with a lower risk of endometrial cancer compared to tamoxifen?
Raloxifene
Which medication inhibits the peripheral conversion of androgens to estrogen and is used in the treatment of ER-positive breast cancer in postmenopausal females?
Anastrozole
Which medication blocks androgen receptors and inhibits 17α-hydroxylase and 17,20-lyase enzymes, and is used in polycystic ovary syndrome (PCOS) to treat hirsutism and amenorrhea?
Spironolactone
Which medication inhibits 5α-reductase enzyme, reducing the conversion of testosterone to dihydrotestosterone (DHT), and is used in benign prostatic hyperplasia (BPH) and male-pattern baldness?
Finasteride
Which medication is a nonsteroidal competitive inhibitor of androgen receptors and is used in the treatment of prostate cancer?
Bicalutamide
Which medication inhibits 17α-hydroxylase and 17,20-lyase enzymes involved in steroid synthesis and is used in prostate cancer treatment?
Abiraterone
Which medication is used to relax the uterus in preterm labor, allowing time for glucocorticoids administration to promote fetal lung maturity or transfer to a medical center with appropriate obstetrical care?
Tocolytics
Which medication is a synthetic androgen with partial agonist activity at androgen receptors and is used in conditions like endometriosis and hereditary angioedema?
Danazol
Which medication is an androgen receptor agonist used to treat hypogonadism and promote the development of secondary sex characteristics?
Testosterone
Which medication is a GnRH antagonist that acts to decrease LH and FSH levels without causing a start-up flare?
Degarelix
Which medication is a GnRH agonist that is used for continuous administration in cancer treatment to downregulate the GnRH receptor in the pituitary gland?
Leuprolide
Which medication is an estrogen receptor (ER) agonist used for hormone replacement therapy in postmenopausal females and treatment of menstrual abnormalities?
Ethinyl Estradiol
Which medication is a GnRH analog that can act as either agonist or antagonist depending on its administration schedule?
Histrelin
Which medication is used in the treatment of uterine fibroids, endometriosis, precocious puberty, prostate cancer, and infertility?
Goserelin
Which medication is a GnRH analog that is used for pulsatile administration in conditions like infertility to stimulate the release of LH and FSH?
Nafarelin
Which medication is a GnRH antagonist used in the treatment of prostate cancer?
Degarelix
Which medication is contraindicated in patients with ER-positive breast cancer and a history of deep vein thrombosis (DVT)?
Ethinyl Estradiol
Which medication is associated with an increased risk of endometrial cancer when given without progesterone, bleeding in postmenopausal patients, and an elevated risk of thrombi (blood clots)?
Ethinyl Estradiol
Which medication is primarily used to treat prostate cancer and acts by downregulating the GnRH receptor in the pituitary gland?
Leuprolide
Test your knowledge on GnRH analogs, synthetic hormones that interact with the pituitary gland to regulate LH and FSH secretion. Discover the clinical uses and mechanisms of GnRH analogs like Leuprolide, Goserelin, Nafarelin, and Histrelin. Can you differentiate between agonists and antagonists? Take the quiz now!
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