Glycosyltransferases in Glycoconjugate Biosynthesis

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Questions and Answers

What is the acceptor specificity of human fucosyltransferases III–VII?

attaching fucose in α1-3-linkage to N-acetyllactosamine moieties on glycans

Give an example of a glycosyltransferase with unusual flexibility in specificity.

β1-4 galactosyltransferase involved in N-acetyllactosamine formation

What is a unique property of some glycosyltransferases in terms of active sites?

Some glycosyltransferases have two separate active sites with different substrate specificities.

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