Glycolysis Overview Quiz

Glycolysis Overview

• Glycolysis occurs in the cytosol of the cell.
• The main product is two three-carbon molecules of pyruvate.
• A net gain of two ATP molecules is obtained from one glucose molecule during glycolysis.
• Substrate-level phosphorylation is the type of phosphorylation that takes place during glycolysis.

Breakdown of Glucose

• Each glucose molecule is broken down into two pyruvate molecules through glycolysis.

Energy-Investing Phase Steps

• The phase involves a series of reactions to prepare glucose for breakdown:
  • Glucose is primed using two ATP molecules.
  • Converted to glucose-6-phosphate.
  • Rearranged to fructose-6-phosphate.
  • Phosphorylated to form fructose-1,6-bisphosphate.
  • Fructose-1,6-bisphosphate is cleaved into dihydroxyacetone phosphate (DAP) and glyceraldehyde-3-phosphate (G3P).
  • DAP is rearranged to form another G3P, resulting in two G3P molecules.

Key Steps in Glycolysis

• The first step involves ATP transferring a phosphate group to glucose, converting it into glucose-6-phosphate.
• Glucose priming is essential as it converts glucose into a cleavable compound for further breakdown.

ATP Usage

• Two ATP molecules are consumed during the priming phase of glycolysis.

Significant Reaction

• In step four, fructose-1,6-bisphosphate splits into DAP and G3P, marking a crucial moment in the glycolytic pathway.