Glycolysis and Pyruvate Metabolism Quiz
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Questions and Answers

Which molecule removes COOH from pyruvate in the mechanism of action of PDH complex?

  • CoASH
  • Lipoamide
  • FAD
  • Thiamine pyrophosphate (TPP) (correct)
  • What is the covalent modification that renders E1 of the PDH complex inactive?

  • Ubiquitination
  • Phosphorylation (correct)
  • Acetylation
  • Methylation
  • What inhibits the PDH complex in an increased energy situation?

  • NAD+
  • ATP (correct)
  • AMP
  • CoA
  • How is the TCA cycle regulated at 3 exergonic steps?

    <p>By substrate availability and accumulation of product</p> Signup and view all the answers

    Which pathway is important for providing NADPH for synthetic reactions?

    <p>Hexose mono phosphate shunt (HMP-shunt)</p> Signup and view all the answers

    Where does the Electron Transport System (ETS) take place?

    <p>Mitochondrial membrane</p> Signup and view all the answers

    What is the purpose of the Hexose mono phosphate shunt (HMP-shunt)?

    <p>Produce NADPH</p> Signup and view all the answers

    Which molecule is used for detoxification of drugs and carcinogens?

    <p>NADPH</p> Signup and view all the answers

    Where does the majority of ATP synthesis occur in cellular respiration?

    <p>Electron Transport Chain</p> Signup and view all the answers

    Which of the following inhibits the flow of H+ through ATP synthase?

    <p>Oligomycin</p> Signup and view all the answers

    What is the byproduct of metabolism that has to be detoxified by glutathione peroxidase?

    <p>Hydrogen peroxide</p> Signup and view all the answers

    Which enzyme is involved in the reduction of oxygen to water in the Electron Transport Chain?

    <p>Cytochrome oxidase</p> Signup and view all the answers

    Which of the following is a synthetic uncoupler of the Electron Transport Chain?

    <p>2,4-dinitrophenol</p> Signup and view all the answers

    What is the purpose of the pentose phosphate pathway?

    <p>Produce NADPH</p> Signup and view all the answers

    Where does the oxidative burst by phagocytic cells to kill microbes occur?

    <p>Spleen</p> Signup and view all the answers

    Which molecule is involved in the reduction of hydrogen peroxide in the cell?

    <p>NADPH</p> Signup and view all the answers

    Which molecule is produced in the Hexose Mono Phosphate (HMP) pathway for the reduction of hydrogen peroxide?

    <p>NADPH</p> Signup and view all the answers

    Where does the majority of ATP synthesis occur in cellular respiration?

    <p>Electron Transport System</p> Signup and view all the answers

    What is the purpose of the Electron Transport System (ETS) in cellular respiration?

    <p>To produce ATP</p> Signup and view all the answers

    Which of the following is a synthetic uncoupler of the Electron Transport Chain (ETC)?

    <p>2,4-dinitrophenol</p> Signup and view all the answers

    Which enzyme is involved in the reduction of oxygen to water in the Electron Transport Chain (ETC)?

    <p>Cytochrome oxidase</p> Signup and view all the answers

    What is the purpose of the Hexose Mono Phosphate (HMP) pathway?

    <p>To produce NADPH and Ribose-5-PO4</p> Signup and view all the answers

    Which molecule is used for reductive biosynthesis such as fatty acid and cholesterol synthesis?

    <p>NADPH</p> Signup and view all the answers

    What inhibits the flow of H+ through ATP synthase in the Electron Transport Chain (ETC)?

    <p>Oligomycin</p> Signup and view all the answers

    Where does the oxidative burst by phagocytic cells to kill microbes occur?

    <p>Phagolysosome</p> Signup and view all the answers

    What is the covalent modification that renders E1 of the Pyruvate Dehydrogenase (PDH) complex inactive?

    <p>Phosphorylation</p> Signup and view all the answers

    Which molecule is involved in the reduction of hydrogen peroxide in the cell?

    <p>NADPH</p> Signup and view all the answers

    Where does the oxidative burst by phagocytic cells to kill microbes occur?

    <p>Phagolysosome</p> Signup and view all the answers

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