Glycogenesis Quiz
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Questions and Answers

Which enzyme is the regulatory enzyme in glycogenesis?

  • Glycogen phosphorylase
  • Glycogen branching enzyme
  • Glycogen debranching enzyme
  • Glycogen synthase (correct)

What are the two forms of glycogen synthase?

  • Active “a” and inactive “b” (correct)
  • Active “a” and inactive “c”
  • Active “b” and inactive “c”
  • Active “b” and inactive “d”

What is the effect of phosphorylation on glycogen synthase?

  • It activates the enzyme
  • It has no effect on the enzyme
  • It inactivates the enzyme (correct)
  • It converts the enzyme into a different enzyme

What enzyme can convert glycogen synthase “b” back to the “a” form?

<p>Protein phosphatase-1 (D)</p> Signup and view all the answers

What is the relationship between the level of inactivation of glycogen synthase and the degree of phosphorylation?

<p>They are directly proportional (A)</p> Signup and view all the answers

What is the active form of glycogen synthase?

<p>“a” form (D)</p> Signup and view all the answers

What is the inactive form of glycogen synthase?

<p>“b” form (A)</p> Signup and view all the answers

What is the process by which glycogen synthase “b” is converted back to the “a” form?

<p>Dephosphorylation (D)</p> Signup and view all the answers

What is the effect of the level of inactivation of glycogen synthase on glycogenesis?

<p>It inhibits glycogenesis (D)</p> Signup and view all the answers

What is the effect of protein phosphatase-1 on glycogen synthase?

<p>It activates the enzyme (A)</p> Signup and view all the answers

Which enzyme is the regulatory enzyme in glycogenesis?

<p>Glycogen synthase (C)</p> Signup and view all the answers

What are the two forms of glycogen synthase?

<p>Active “a” and inactive “b” (D)</p> Signup and view all the answers

What is the effect of phosphorylation on glycogen synthase?

<p>It inactivates the enzyme (A)</p> Signup and view all the answers

What enzyme can convert glycogen synthase “b” back to the “a” form?

<p>Protein phosphatase-1 (B)</p> Signup and view all the answers

What is the relationship between the level of inactivation of glycogen synthase and the degree of phosphorylation?

<p>They are directly proportional (B)</p> Signup and view all the answers

What is the active form of glycogen synthase?

<p>“a” form (C)</p> Signup and view all the answers

What is the inactive form of glycogen synthase?

<p>“b” form (D)</p> Signup and view all the answers

What is the process by which glycogen synthase “b” is converted back to the “a” form?

<p>Dephosphorylation (D)</p> Signup and view all the answers

What is the effect of the level of inactivation of glycogen synthase on glycogenesis?

<p>It inhibits glycogenesis (D)</p> Signup and view all the answers

What is the effect of protein phosphatase-1 on glycogen synthase?

<p>It activates the enzyme (A)</p> Signup and view all the answers

Which enzyme is the regulatory enzyme in glycogenesis?

<p>Glycogen synthase (B)</p> Signup and view all the answers

What are the two forms of glycogen synthase?

<p>Phosphorylated and dephosphorylated (A)</p> Signup and view all the answers

How is glycogen synthase 'a' converted to the 'b' form?

<p>By phosphorylation (D)</p> Signup and view all the answers

What is the level of inactivation of glycogen synthase 'b' proportional to?

<p>Its degree of phosphorylation (D)</p> Signup and view all the answers

Which enzyme can reconvert glycogen synthase 'b' to the 'a' form?

<p>Protein phosphatase-1 (C)</p> Signup and view all the answers

What is the role of glycogen synthase in glycogenesis?

<p>To synthesize glycogen from glucose (C)</p> Signup and view all the answers

What is the difference between glycogen synthase 'a' and 'b'?

<p>Their degree of phosphorylation (B)</p> Signup and view all the answers

What is the effect of protein phosphatase-1 on glycogen synthase 'b'?

<p>It dephosphorylates it (A)</p> Signup and view all the answers

What is the relationship between the level of phosphorylation and the level of inactivation of glycogen synthase 'b'?

<p>They are directly related (D)</p> Signup and view all the answers

What is the effect of phosphorylation on glycogen synthase 'a'?

<p>It deactivates it (C)</p> Signup and view all the answers

Flashcards

Glycogen Synthase

The enzyme that controls the synthesis of glycogen from glucose.

Active form of Glycogen Synthase

Glycogen Synthase 'a' - the form that synthesizes glycogen.

Inactive form of Glycogen Synthase

Glycogen Synthase 'b' – the form that doesn't synthesize glycogen.

Phosphorylation

Adding phosphate groups to a molecule, often changing its activity.

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Dephosphorylation

Removing phosphate groups, often changing a molecule's activity.

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Protein Phosphatase-1

The enzyme that dephosphorylates Glycogen Synthase 'b', activating it.

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Effect of Phosphorylation on Glycogen Synthase

Phosphorylation inactivates Glycogen Synthase.

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Phosphorylation and Glycogen Synthase Inactivation

The level of Glycogen Synthase inactivation is directly proportional to the degree of its phosphorylation.

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Effect of Protein Phosphatase-1 on Glycogen Synthase

Protein Phosphatase-1 activates Glycogen Synthase.

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Glycogenesis

The process of storing glucose as glycogen.

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Effect of Glycogen Synthase Inactivation on Glycogenesis

Inactivation of Glycogen Synthase inhibits glycogenesis.

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Glycogen Synthase 'a' vs. 'b'

These are the active and inactive forms of glycogen synthase, distinguished by their phosphorylation state.

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Study Notes

Glycogen Synthase and Glycogenesis

  • Glycogen synthase is the regulatory enzyme in glycogenesis.
  • There are two forms of glycogen synthase: 'a' (active form) and 'b' (inactive form).

Phosphorylation and Glycogen Synthase

  • Phosphorylation of glycogen synthase 'a' leads to its conversion to the 'b' form.
  • The level of inactivation of glycogen synthase 'b' is proportional to the degree of phosphorylation.

Conversion of Glycogen Synthase 'b' to 'a'

  • Protein phosphatase-1 can reconvert glycogen synthase 'b' back to the 'a' form.
  • The process of converting glycogen synthase 'b' back to 'a' involves dephosphorylation.

Effects of Glycogen Synthase Inactivation

  • The level of inactivation of glycogen synthase affects glycogenesis, with higher levels of inactivation resulting in decreased glycogenesis.
  • Protein phosphatase-1 has a positive effect on glycogen synthase, reactivating it.

Role of Glycogen Synthase

  • Glycogen synthase plays a crucial role in glycogenesis, catalyzing the formation of glycogen from glucose.
  • The difference between glycogen synthase 'a' and 'b' lies in their activity, with 'a' being active and 'b' being inactive.

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Description

Test your knowledge of glycogenesis with this quiz! Learn about the regulatory enzyme, glycogen synthase, and its active and inactive forms. Explore the process of phosphorylation and how it affects the activity of the enzyme. Challenge yourself to identify how glycogen synthase "b" can be converted back to the active "a" form. Perfect for students and professionals in the fields of biochemistry and metabolism.

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