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Gluconeogenesis Overview

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Questions and Answers

What does fructose 2,6-bisphosphate inhibit?

Ketone bodies

Fructose-1,6-bisphosphatase (correct)

Phosphofructokinase-1

Fatty acids

Which process involves the synthesis of glucose from non-carbohydrate sources?

Ketogenesis

Glycolysis

Gluconeogenesis (correct)

Lipolysis

Which enzyme is an allosteric activator of phosphofructokinase-1?

PFKFB (correct)

FBPase-1

Fructose-1,6-bisphosphatase

PFK-1

What is the alternative energy source provided by lipolysis?

Fatty acids Signup and view all the answers

What does ketogenesis stimulate the production of from fatty acids?

Ketone bodies Signup and view all the answers

What metabolic pathway does F2,6BP inhibit?

Gluconeogenesis Signup and view all the answers

What does PFK-1 enzyme promote the conversion of?

[[Fructose-1,6-bisphosphate]] Signup and view all the answers

What is the role of F2,6BP in glycolysis?

[[Inhibit FBPase-1]] Signup and view all the answers

What is the primary function of lipolysis?

Facilitating breakdown of fats into fatty acids and glycerol Signup and view all the answers

What is the role of F2,6BP in regulating glycolysis?

Enhances glycolytic flux Signup and view all the answers

How does glucagon influence energy metabolism during fasting or low-blood-sugar conditions?

Promotes lipolysis and ketogenesis Signup and view all the answers

Which enzyme does F2,6BP inhibit in the metabolic pathway?

FBPase-1 Signup and view all the answers

What is the effect of F2,6BP on the enzyme PFK-1?

Activates PFK-1 Signup and view all the answers

How does F2,6BP contribute to maintaining the directionality of metabolic pathways?

By inhibiting FBPase-1 Signup and view all the answers

Which enzyme is responsible for tightly regulating the levels of F2,6BP?

PFKFB Signup and view all the answers