Gluconeogenesis Overview

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15 Questions

What does fructose 2,6-bisphosphate inhibit?

Fructose-1,6-bisphosphatase

Which process involves the synthesis of glucose from non-carbohydrate sources?

Gluconeogenesis

Which enzyme is an allosteric activator of phosphofructokinase-1?

PFKFB

What is the alternative energy source provided by lipolysis?

Fatty acids

What does ketogenesis stimulate the production of from fatty acids?

Ketone bodies

What metabolic pathway does F2,6BP inhibit?

Gluconeogenesis

What does PFK-1 enzyme promote the conversion of?

[[Fructose-1,6-bisphosphate]]

What is the role of F2,6BP in glycolysis?

[[Inhibit FBPase-1]]

What is the primary function of lipolysis?

Facilitating breakdown of fats into fatty acids and glycerol

What is the role of F2,6BP in regulating glycolysis?

Enhances glycolytic flux

How does glucagon influence energy metabolism during fasting or low-blood-sugar conditions?

Promotes lipolysis and ketogenesis

Which enzyme does F2,6BP inhibit in the metabolic pathway?

FBPase-1

What is the effect of F2,6BP on the enzyme PFK-1?

Activates PFK-1

How does F2,6BP contribute to maintaining the directionality of metabolic pathways?

By inhibiting FBPase-1

Which enzyme is responsible for tightly regulating the levels of F2,6BP?

PFKFB

Learn about gluconeogenesis, the metabolic process of synthesizing glucose from noncarbohydrate sources like pyruvate, lactate, and amino acids. Understand the importance of gluconeogenesis in maintaining glucose levels during fasting and supplying glucose for the brain's energy needs.

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