Gluconeogenesis Overview
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Questions and Answers

What does fructose 2,6-bisphosphate inhibit?

  • Ketone bodies
  • Fructose-1,6-bisphosphatase (correct)
  • Phosphofructokinase-1
  • Fatty acids

Which process involves the synthesis of glucose from non-carbohydrate sources?

  • Ketogenesis
  • Glycolysis
  • Gluconeogenesis (correct)
  • Lipolysis

Which enzyme is an allosteric activator of phosphofructokinase-1?

  • PFKFB (correct)
  • FBPase-1
  • Fructose-1,6-bisphosphatase
  • PFK-1

What is the alternative energy source provided by lipolysis?

<p>Fatty acids (C)</p> Signup and view all the answers

What does ketogenesis stimulate the production of from fatty acids?

<p>Ketone bodies (B)</p> Signup and view all the answers

What metabolic pathway does F2,6BP inhibit?

<p>Gluconeogenesis (B)</p> Signup and view all the answers

What does PFK-1 enzyme promote the conversion of?

<p>[[Fructose-1,6-bisphosphate]] (C)</p> Signup and view all the answers

What is the role of F2,6BP in glycolysis?

<p>[[Inhibit FBPase-1]] (D)</p> Signup and view all the answers

What is the primary function of lipolysis?

<p>Facilitating breakdown of fats into fatty acids and glycerol (C)</p> Signup and view all the answers

What is the role of F2,6BP in regulating glycolysis?

<p>Enhances glycolytic flux (D)</p> Signup and view all the answers

How does glucagon influence energy metabolism during fasting or low-blood-sugar conditions?

<p>Promotes lipolysis and ketogenesis (D)</p> Signup and view all the answers

Which enzyme does F2,6BP inhibit in the metabolic pathway?

<p>FBPase-1 (D)</p> Signup and view all the answers

What is the effect of F2,6BP on the enzyme PFK-1?

<p>Activates PFK-1 (C)</p> Signup and view all the answers

How does F2,6BP contribute to maintaining the directionality of metabolic pathways?

<p>By inhibiting FBPase-1 (D)</p> Signup and view all the answers

Which enzyme is responsible for tightly regulating the levels of F2,6BP?

<p>PFKFB (B)</p> Signup and view all the answers

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