Glycolysis and Gluconeogenesis slides quiz

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Which phase of glycolysis is responsible for generating ATP?

Both phases generate ATP

Phase II: ATP-generating phase (correct)

Neither phase generates ATP

Phase I: Preparative Phase

Which enzyme is responsible for the first reaction of glycolysis?

Triose Phosphate Isomerase

Hexokinase (correct)

Aldolase

Enolase

Which step(s) of glycolysis are irreversible?

Reaction 3

Reaction 1

Reaction 2

Both Reaction 1 and Reaction 2 (correct)

What is the role of Mg2+ cofactor in glycolysis?

To catalyze Reaction 1 Signup and view all the answers

Which step of glycolysis requires an input of energy?

Reaction 1 Signup and view all the answers

Which step of glycolysis produces energy directly?

Reaction 3 Signup and view all the answers

What is the net energy yield from a cycle of glycolysis?

2 ATP Signup and view all the answers

Which of the following reactions is the rate-limiting and committing step of glycolysis?

Reaction 3 Signup and view all the answers

What is the standard Gibbs free energy change ($\Delta G^0$) for Reaction 4 in glycolysis?

+23.9 kJ/mol Signup and view all the answers

Which enzyme catalyzes Reaction 9 in glycolysis?

Enolase Signup and view all the answers

How many ATP molecules are required during the preparatory phase of glycolysis?

2 ATP Signup and view all the answers

What is the net ATP production per glucose molecule in glycolysis through substrate-level phosphorylation?

2 ATP Signup and view all the answers

What happens to pyruvate under aerobic conditions?

It enters the citric acid cycle Signup and view all the answers

Which of the following reactions is NOT one of the three irreversible reactions in glycolysis?

Reaction 5: Triose phosphate isomerase Signup and view all the answers

Which enzyme is responsible for the carboxylation of pyruvate in the gluconeogenesis pathway?

Pyruvate carboxylase Signup and view all the answers

Which enzyme is responsible for the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate in the gluconeogenesis pathway?

Fructose 1,6-bisphosphatase Signup and view all the answers

Which enzyme is responsible for the conversion of glucose 6-phosphate to glucose in the gluconeogenesis pathway?

Glucose-6 Phosphatase Signup and view all the answers

Which of the following is NOT a precursor for gluconeogenesis?

Pyruvate Signup and view all the answers

Which of the following is a glucogenic amino acid?

Alanine Signup and view all the answers

What is the cellular location of pyruvate carboxylase?

Mitochondria Signup and view all the answers

What is the main symptom of inherited disorders of gluconeogenesis?

Poor growth and development Signup and view all the answers

Which shuttle system is used when the starting substrate is alanine?

Malate shuttle Signup and view all the answers

What is the product of the malate shuttle once it crosses the inner mitochondrial membrane?

Malate Signup and view all the answers

What is malate converted back to in the cytosol?

Oxaloacetate Signup and view all the answers

What is the starting substrate for the shuttle for lactate?

Lactate Signup and view all the answers

What is pyruvate converted to in the mitochondria during the shuttle for lactate?

Oxaloacetate Signup and view all the answers

Glycolysis and Gluconeogenesis slides quiz

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Questions and Answers

Which phase of glycolysis is responsible for generating ATP?

Which enzyme is responsible for the first reaction of glycolysis?

Which step(s) of glycolysis are irreversible?

What is the role of Mg2+ cofactor in glycolysis?

Which step of glycolysis requires an input of energy?

Which step of glycolysis produces energy directly?

What is the net energy yield from a cycle of glycolysis?

Which of the following reactions is the rate-limiting and committing step of glycolysis?

What is the standard Gibbs free energy change ($\Delta G^0$) for Reaction 4 in glycolysis?

Which enzyme catalyzes Reaction 9 in glycolysis?

How many ATP molecules are required during the preparatory phase of glycolysis?

What is the net ATP production per glucose molecule in glycolysis through substrate-level phosphorylation?

What happens to pyruvate under aerobic conditions?

Which of the following reactions is NOT one of the three irreversible reactions in glycolysis?

Which enzyme is responsible for the carboxylation of pyruvate in the gluconeogenesis pathway?

Which enzyme is responsible for the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate in the gluconeogenesis pathway?

Which enzyme is responsible for the conversion of glucose 6-phosphate to glucose in the gluconeogenesis pathway?

Which of the following is NOT a precursor for gluconeogenesis?

Which of the following is a glucogenic amino acid?

What is the cellular location of pyruvate carboxylase?

What is the main symptom of inherited disorders of gluconeogenesis?

Which shuttle system is used when the starting substrate is alanine?

What is the product of the malate shuttle once it crosses the inner mitochondrial membrane?

What is malate converted back to in the cytosol?

What is the starting substrate for the shuttle for lactate?

What is pyruvate converted to in the mitochondria during the shuttle for lactate?

What is phosphoenolpyruvate (PEP) shuttled out of the mitochondria to continue with gluconeogenesis?

What can glycerol be converted to in gluconeogenesis?

Which process is shown in the image labeled 'Glycolysis & Gluconeogenesis'?

Which shuttle system is used when the starting substrate is glucose?

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