Glycolysis and Gluconeogenesis slides quiz
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Questions and Answers

Which phase of glycolysis is responsible for generating ATP?

  • Both phases generate ATP
  • Phase II: ATP-generating phase (correct)
  • Neither phase generates ATP
  • Phase I: Preparative Phase

Which enzyme is responsible for the first reaction of glycolysis?

  • Triose Phosphate Isomerase
  • Hexokinase (correct)
  • Aldolase
  • Enolase

Which step(s) of glycolysis are irreversible?

  • Reaction 3
  • Reaction 1
  • Reaction 2
  • Both Reaction 1 and Reaction 2 (correct)

What is the role of Mg2+ cofactor in glycolysis?

<p>To catalyze Reaction 1 (C)</p> Signup and view all the answers

Which step of glycolysis requires an input of energy?

<p>Reaction 1 (A)</p> Signup and view all the answers

Which step of glycolysis produces energy directly?

<p>Reaction 3 (A)</p> Signup and view all the answers

What is the net energy yield from a cycle of glycolysis?

<p>2 ATP (C)</p> Signup and view all the answers

Which of the following reactions is the rate-limiting and committing step of glycolysis?

<p>Reaction 3 (D)</p> Signup and view all the answers

What is the standard Gibbs free energy change ($\Delta G^0$) for Reaction 4 in glycolysis?

<p>+23.9 kJ/mol (D)</p> Signup and view all the answers

Which enzyme catalyzes Reaction 9 in glycolysis?

<p>Enolase (C)</p> Signup and view all the answers

How many ATP molecules are required during the preparatory phase of glycolysis?

<p>2 ATP (A)</p> Signup and view all the answers

What is the net ATP production per glucose molecule in glycolysis through substrate-level phosphorylation?

<p>2 ATP (A)</p> Signup and view all the answers

What happens to pyruvate under aerobic conditions?

<p>It enters the citric acid cycle (B)</p> Signup and view all the answers

Which of the following reactions is NOT one of the three irreversible reactions in glycolysis?

<p>Reaction 5: Triose phosphate isomerase (C)</p> Signup and view all the answers

Which enzyme is responsible for the carboxylation of pyruvate in the gluconeogenesis pathway?

<p>Pyruvate carboxylase (A)</p> Signup and view all the answers

Which enzyme is responsible for the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate in the gluconeogenesis pathway?

<p>Fructose 1,6-bisphosphatase (C)</p> Signup and view all the answers

Which enzyme is responsible for the conversion of glucose 6-phosphate to glucose in the gluconeogenesis pathway?

<p>Glucose-6 Phosphatase (C)</p> Signup and view all the answers

Which of the following is NOT a precursor for gluconeogenesis?

<p>Pyruvate (D)</p> Signup and view all the answers

Which of the following is a glucogenic amino acid?

<p>Alanine (C)</p> Signup and view all the answers

What is the cellular location of pyruvate carboxylase?

<p>Mitochondria (A)</p> Signup and view all the answers

What is the main symptom of inherited disorders of gluconeogenesis?

<p>Poor growth and development (D)</p> Signup and view all the answers

Which shuttle system is used when the starting substrate is alanine?

<p>Malate shuttle (C)</p> Signup and view all the answers

What is the product of the malate shuttle once it crosses the inner mitochondrial membrane?

<p>Malate (C)</p> Signup and view all the answers

What is malate converted back to in the cytosol?

<p>Oxaloacetate (C)</p> Signup and view all the answers

What is the starting substrate for the shuttle for lactate?

<p>Lactate (A)</p> Signup and view all the answers

What is pyruvate converted to in the mitochondria during the shuttle for lactate?

<p>Oxaloacetate (D)</p> Signup and view all the answers

What is phosphoenolpyruvate (PEP) shuttled out of the mitochondria to continue with gluconeogenesis?

<p>Phosphoenolpyruvate (C)</p> Signup and view all the answers

What can glycerol be converted to in gluconeogenesis?

<p>Dihydroxyacetone phosphate (B)</p> Signup and view all the answers

Which process is shown in the image labeled 'Glycolysis & Gluconeogenesis'?

<p>Gluconeogenesis (D)</p> Signup and view all the answers

Which shuttle system is used when the starting substrate is glucose?

<p>Oxaloacetate shuttle (B)</p> Signup and view all the answers

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