Podcast
Questions and Answers
What is the main purpose of acetyl-CoA in the Krebs cycle?
What is the main purpose of acetyl-CoA in the Krebs cycle?
- To facilitate the breakdown of glycogen into glucose during glycogenolysis
- To convert pyruvate into glucose during gluconeogenesis
- To synthesize fatty acids for energy storage
- To produce energy-rich molecules like NADH and FADH2 (correct)
Which process involves the conversion of non-carbohydrate sources, like amino acids, into glucose?
Which process involves the conversion of non-carbohydrate sources, like amino acids, into glucose?
- TCA cycle
- Glycogenolysis
- Ketogenesis
- Gluconeogenesis (correct)
During which metabolic process are fatty acids broken down to generate ATP?
During which metabolic process are fatty acids broken down to generate ATP?
- TCA cycle (correct)
- Gluconeogenesis
- Glycogenolysis
- Ketogenesis
What process will take place as a substitute to maintain Mr. GB's glucose level during fasting?
What process will take place as a substitute to maintain Mr. GB's glucose level during fasting?
Where does the conversion of alanine and glycerol to glucose mainly occur to maintain glucose levels?
Where does the conversion of alanine and glycerol to glucose mainly occur to maintain glucose levels?
During short-term maximum exertion, what will provide the main fuel for muscle contraction?
During short-term maximum exertion, what will provide the main fuel for muscle contraction?
Which amino acid is the major contributor to transporting nitrogen for excretion as urea?
Which amino acid is the major contributor to transporting nitrogen for excretion as urea?
Which process do mitochondria in the cell NOT carry out?
Which process do mitochondria in the cell NOT carry out?
Which substrate does NOT contribute to net gluconeogenesis in the liver?
Which substrate does NOT contribute to net gluconeogenesis in the liver?
Which enzyme is NOT involved in the flow of carbon from glucose to lactate (glycolysis) and gluconeogenesis?
Which enzyme is NOT involved in the flow of carbon from glucose to lactate (glycolysis) and gluconeogenesis?
A child with an enlarged liver is diagnosed with glucose-6-phosphatase deficiency. Which process is directly affected by this deficiency?
A child with an enlarged liver is diagnosed with glucose-6-phosphatase deficiency. Which process is directly affected by this deficiency?
Flashcards
Acetyl-CoA's role in Krebs cycle
Acetyl-CoA's role in Krebs cycle
Produces energy-rich molecules like NADH and FADH2.
Gluconeogenesis
Gluconeogenesis
Conversion of non-carbohydrate sources to glucose.
Fatty acid breakdown
Fatty acid breakdown
Breaks fatty acids down to generate ATP.
Fasting glucose maintenance
Fasting glucose maintenance
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Glucose level maintenance site
Glucose level maintenance site
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Short-term exertion fuel
Short-term exertion fuel
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Major nitrogen excretion amino acid
Major nitrogen excretion amino acid
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Mitochondria function EXCLUDED
Mitochondria function EXCLUDED
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Non-gluconeogenic substrate
Non-gluconeogenic substrate
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Enzyme NOT in glucose-lactate flow
Enzyme NOT in glucose-lactate flow
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Process affected by glucose-6-phosphatase def.
Process affected by glucose-6-phosphatase def.
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Study Notes
Krebs Cycle and Energy Production
- Acetyl-CoA plays a crucial role in the Krebs cycle by facilitating the production of ATP.
Gluconeogenesis
- Gluconeogenesis is the process that converts non-carbohydrate sources, like amino acids, into glucose.
- During fasting, gluconeogenesis takes place to maintain glucose levels.
- The conversion of alanine and glycerol to glucose mainly occurs in the liver to maintain glucose levels.
Fatty Acid Breakdown
- Fatty acids are broken down to generate ATP during beta-oxidation.
Muscle Contraction
- During short-term maximum exertion, ATP produced from anaerobic glycolysis provides the main fuel for muscle contraction.
Nitrogen Transport and Excretion
- Alanine is the major contributor to transporting nitrogen for excretion as urea.
Mitochondrial Function
- Mitochondria do not carry out gluconeogenesis.
Gluconeogenesis Substrates
- Alanine and glycerol contribute to net gluconeogenesis in the liver.
- Pyruvate does not contribute to net gluconeogenesis in the liver.
Glycolysis and Gluconeogenesis Enzymes
- Phosphofructokinase-1 is involved in the flow of carbon from glucose to lactate (glycolysis) and gluconeogenesis.
- Glucose-6-phosphatase is involved in gluconeogenesis.
Glucose-6-Phosphatase Deficiency
- A deficiency in glucose-6-phosphatase directly affects gluconeogenesis.
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Description
Test your knowledge on gluconeogenesis and glycogenolysis processes in maintaining blood glucose levels. Learn about how the body converts different substances to glucose when fasting. Answer questions related to liver and muscle glycogen usage, as well as the conversion of alanine and glycerol to glucose.
