Respiratory System 1
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Questions and Answers

What is the main function of mast cell stabilizers in the treatment of asthma?

  • Enhance inflammatory response in the airways
  • Induce bronchodilation
  • Reduce bronchial inflammation (correct)
  • Increase bronchial hyper-reactivity
  • What is a characteristic of glucocorticoids in asthma treatment?

  • Rapid onset of action within a few minutes
  • Promote bronchial hyper-reactivity
  • Cause immediate bronchodilation
  • Reduce inflammation in the bronchial tubes (correct)
  • Which of the following is true about the routes of administration for glucocorticoids in asthma treatment?

  • Topical application is recommended for long-term therapy
  • Intravenous administration is the most common route
  • Oral inhalation is preferred for local action in the airways (correct)
  • Subcutaneous injections are used for rapid systemic effects
  • What is a common side effect of glucocorticoids used in asthma treatment?

    <p>Hyperglycemia</p> Signup and view all the answers

    What happens when glucocorticoids are abruptly withdrawn after long-term use in asthma treatment?

    <p>Rebound worsening of symptoms and adrenal insufficiency</p> Signup and view all the answers

    What is the primary mechanism of action of glucocorticoids in treating asthma?

    <p>Reduction in the number of inflammatory cells in airways</p> Signup and view all the answers

    Which route of administration is considered the best choice for glucocorticoids in the treatment of asthma due to having fewer side effects?

    <p>Inhalation</p> Signup and view all the answers

    What is a common side effect associated with systemic administration of glucocorticoids?

    <p>Adrenal suppression</p> Signup and view all the answers

    Which symptom is indicative of adrenal crisis, a life-threatening condition when corticosteroids are abruptly stopped?

    <p>Lightheadedness and weakness</p> Signup and view all the answers

    What is the primary effect of mast cell stabilizers like Cromolyn (cromoglycate) in treating asthma?

    <p>Stabilization of mast cell membrane</p> Signup and view all the answers

    Which of the following is NOT a common side effect associated with inhalation of glucocorticoids?

    <p>Adrenal suppression</p> Signup and view all the answers

    What is the route of administration for epinephrine to treat acute anaphylaxis?

    <p>Subcutaneous or inhalation</p> Signup and view all the answers

    Which of the following is a disadvantage of using epinephrine for acute anaphylaxis?

    <p>Contraindicated in diabetic patients</p> Signup and view all the answers

    What is the main drug of choice for the treatment of acute anaphylaxis?

    <p>Epinephrine</p> Signup and view all the answers

    Which of the following side effects is NOT associated with the use of epinephrine?

    <p>Hypotension</p> Signup and view all the answers

    Why is Salmeterol not used to relieve acute episodes of asthma?

    <p>Long duration of action</p> Signup and view all the answers

    What is the preferred route of administration for Albuterol in the management of acute episodic attack of asthma?

    <p>Inhalation</p> Signup and view all the answers

    What is the primary route of administration for Albuterol, Terbutaline, and Salmeterol?

    <p>By inhalation</p> Signup and view all the answers

    Which of the following is a common disadvantage of using long-acting beta2 agonists like Salmeterol and Formoterol?

    <p>Used for acute episodes of asthma</p> Signup and view all the answers

    What is a characteristic of Albuterol's onset of action?

    <p>Immediate onset (within 5 minutes)</p> Signup and view all the answers

    Why are glucocorticoids considered important in asthma treatment?

    <p>They have anti-inflammatory properties</p> Signup and view all the answers

    Which medication is the drug of choice for acute anaphylaxis due to its quick onset and short duration of action?

    <p>Terbutaline</p> Signup and view all the answers

    What are the main disadvantages associated with ß2 agonists?

    <p>Skeletal muscle tremors and tachycardia overdose</p> Signup and view all the answers

    Which medication is suitable for asthmatic patients with hypertension or heart failure due to minimal cardiovascular side effects?

    <p>Ipratropium</p> Signup and view all the answers

    Which bronchodilator has a longer duration of action among the quick relief medications mentioned?

    <p>Tiotropium</p> Signup and view all the answers

    What is the main pharmacodynamic difference between ß2-agonists and muscarinic antagonists as quick relief medications?

    <p>Bronchial muscle relaxation</p> Signup and view all the answers

    Which drug, by inhibiting bronchoconstriction and mucus secretion, is less effective than ß2-agonists among the quick relief medications?

    <p>Ipratropium</p> Signup and view all the answers

    In bronchial asthma treatment, which medication is classified as a quick relief medication?

    <p>Leukotrienes antagonists</p> Signup and view all the answers

    What is the primary mechanism of action of short-acting beta2 agonists in asthma management?

    <p>Stimulating adenyl cyclase</p> Signup and view all the answers

    Which of the following is considered a long-acting beta2 agonist used in the maintenance therapy of bronchial asthma?

    <p>Salmeterol</p> Signup and view all the answers

    What is the main function of anti-inflammatory agents in the treatment of asthma?

    <p>Reducing airway inflammation</p> Signup and view all the answers

    Which of the following is a common side effect associated with the use of anti-IgE monoclonal antibody in asthma treatment?

    <p>Bronchospasm</p> Signup and view all the answers

    Which of the following is a common side effect associated with the use of anti-IgE monoclonal antibody in asthma treatment?

    <p>Headache</p> Signup and view all the answers

    What is a characteristic of short-acting beta2 agonists in asthma management?

    <p>Inhibit bronchoconstriction and mucus secretion</p> Signup and view all the answers

    What is a common misconception about short-acting beta2 agonists?

    <p>They have a long onset of action</p> Signup and view all the answers

    Which of the following is a disadvantage associated with using short-acting beta2 agonists like albuterol?

    <p>Quick tolerance development</p> Signup and view all the answers

    Why are short-acting beta2 agonists considered the main choice in acute severe asthma?

    <p>They provide quick relief by inhibiting bronchoconstriction</p> Signup and view all the answers

    What is a common side effect associated with the prolonged use of short-acting beta2 agonists?

    <p>Tachycardia</p> Signup and view all the answers

    What distinguishes short-acting beta2 agonists from long-acting beta2 agonists?

    <p>Quick onset of action</p> Signup and view all the answers

    Which statement best describes the pharmacodynamics of short-acting beta2 agonists?

    <p>They primarily focus on relaxing bronchial muscles</p> Signup and view all the answers

    What is a potential concern regarding the overuse of short-acting beta2 agonists?

    <p>Development of tolerance to their effects</p> Signup and view all the answers

    Which of the following is a common misconception about the duration of action of short-acting beta2 agonists?

    <p>Their effects last for an extended period even after administration</p> Signup and view all the answers

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